Best TWAS P=2.6e-08 · Best GWAS P=3.4e-07 conditioned to 0.293
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | AP3B1 | 0.02 | 0.00 | blup | 126 | 0.01 | 0.0182 | -4.8 | -5.3 | 1.1e-07 | 0.86 | 0.02 | 0.84 | FALSE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | AP3B1 | 0.05 | 0.02 | blup | 126 | 0.03 | 0.0005 | 4.9 | -5.6 | 2.6e-08 | 0.80 | 0.02 | 0.90 | TRUE |