Best TWAS P=1.37e-08 · Best GWAS P=6.13e-08 conditioned to 0.585
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | HINT1 | 0.1 | 0.07 | enet | 16 | 0.06 | 8.8e-06 | -5.2 | -5.7 | 1.4e-08 | 0.92 | 0.02 | 0.97 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | HINT1 | 0.1 | 0.06 | lasso | 2 | 0.05 | 2.1e-04 | -4.6 | -5.3 | 1.5e-07 | 0.86 | 0.04 | 0.95 | FALSE |