Best TWAS P=4.29e-09 · Best GWAS P=4.2e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | HEY2 | 0.15 | 0.20 | lasso | 10 | 0.21 | 6.7e-25 | -5.6 | -5.6 | 1.8e-08 | 0.98 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Testis | HEY2 | 0.31 | 0.17 | lasso | 5 | 0.19 | 7.4e-09 | -5.9 | -5.9 | 4.8e-09 | 1.00 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Thyroid | HEY2 | 0.22 | 0.24 | lasso | 6 | 0.23 | 1.0e-17 | -5.9 | -5.9 | 4.3e-09 | 0.99 | 0.00 | 1.00 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | HEY2 | 0.10 | 0.12 | enet | 15 | 0.13 | 9.8e-17 | 5.6 | -5.3 | 1.0e-07 | 0.97 | 0.01 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | HEY2 | 0.03 | 0.04 | lasso | 3 | 0.02 | 3.8e-03 | 5.0 | -5.2 | 2.3e-07 | 0.89 | 0.02 | 0.96 | FALSE |