Best TWAS P=4.29e-09 · Best GWAS P=8.15e-10 conditioned to 0.000262
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | TMEM245 | 0.37 | 0.07 | lasso | 7 | 0.19 | 4.7e-15 | -4.9 | -5.2 | 1.5e-07 | 0.51 | 0.66 | 0.34 | FALSE |
| 2 | NTR | Blood | C9orf5 | 0.05 | 0.02 | enet | 14 | 0.03 | 2.2e-10 | 3.2 | -5.9 | 4.3e-09 | 0.51 | 0.66 | 0.34 | TRUE |
| 3 | The Cancer Genome Atlas | Stomach Adenocarcinoma | C9orf5 | 0.06 | 0.06 | blup | 88 | 0.03 | 3.0e-03 | -4.4 | -5.4 | 7.6e-08 | 0.52 | 0.01 | 0.76 | FALSE |