Best TWAS P=3.51e-15 · Best GWAS P=6.28e-19 conditioned to 1.03e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Muscularis | NEGR1 | 0.13 | 0.04 | lasso | 3 | 0.05 | 5.1e-04 | -5.6 | 6.3 | 3.1e-10 | -0.45 | 0.63 | 0.22 | FALSE |
2 | ROSMAP | Brain Pre-frontal Cortex | NEGR1 | 0.24 | 0.15 | lasso | 8 | 0.22 | 1.3e-27 | 5.3 | 7.9 | 3.5e-15 | -0.78 | 0.07 | 0.93 | TRUE |