TWAS
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Traits
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Traits
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Hip circumference
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chr2:15,703-1,384,725
Best TWAS P=5.03e-08 · Best GWAS P=1.89e-49 conditioned to 3.35e-43
0
0.2M
0.4M
0.6M
0.8M
1M
1.2M
1.4M
0
10
20
30
40
50
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Esophagus Muscularis
AC092159.2
0.26
0.16
enet
7
0.20
5.3e-12
4.8
5.5
5.0e-08
-0.30
1
0
TRUE
1
GTEx
Artery Tibial
AC092159.2
0.38
0.24
lasso
5
0.30
5.6e-24
4.8
5.3
1.2e-07
-0.19
1
0
FALSE
2
GTEx
Esophagus Muscularis
TMEM18
0.37
0.20
lasso
8
0.18
2.0e-11
4.8
5.2
1.9e-07
-0.28
1
0
FALSE