[Hub]/) : Traits : Hip circumference : ← →

chr2:24,324,172-26,088,769

Best TWAS P=6.65e-27 · Best GWAS P=1.35e-23 conditioned to 0.806

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ADCY3	0.16	0.12	lasso	10	0.14	3.2e-17	9.5	-10.7	6.6e-27	-0.87	0.01	0.99	TRUE
26	The Cancer Genome Atlas	Stomach Adenocarcinoma	POMC	0.14	0.00	blup	40	0.02	2.2e-02	-3.9	-5.4	6.5e-08	-0.14	0.01	0.18	TRUE
9	GTEx	Nerve Tibial	ADCY3	0.09	0.05	enet	6	0.03	2.2e-03	7.9	-9.8	8.6e-23	-0.91	0.02	0.98	FALSE
13	GTEx	Whole Blood	RP11-443B20.1	0.21	0.17	enet	32	0.20	1.8e-18	8.4	9.8	1.3e-22	0.86	0.80	0.20	FALSE
10	GTEx	Nerve Tibial	RP11-443B20.1	0.07	0.03	enet	6	0.02	1.1e-02	7.9	-9.7	3.1e-22	-0.81	0.04	0.95	FALSE
12	GTEx	Whole Blood	ADCY3	0.23	0.24	enet	24	0.27	5.5e-25	8.5	9.5	2.3e-21	0.86	1.00	0.00	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	ADCY3	0.17	0.26	enet	32	0.26	6.8e-33	8.5	-9.1	6.0e-20	-0.89	0.77	0.23	FALSE
8	GTEx	Cells EBV-transformed lymphocytes	RP11-443B20.1	0.13	0.13	enet	9	0.05	9.2e-03	8.5	-9.0	1.9e-19	-0.93	0.01	0.97	FALSE
5	GTEx	Artery Tibial	ADCY3	0.21	0.14	lasso	6	0.15	4.3e-12	7.9	8.9	4.8e-19	0.69	0.98	0.02	FALSE
11	GTEx	Whole Blood	DNAJC27	0.08	0.10	lasso	1	0.10	2.2e-09	8.4	8.4	5.7e-17	0.80	0.93	0.07	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADCY3	0.03	0.02	blup	81	0.02	7.1e-04	5.0	-8.1	4.1e-16	-0.87	0.04	0.92	FALSE
3	GTEx	Adipose Subcutaneous	ADCY3	0.07	0.04	lasso	6	0.01	3.2e-02	8.5	7.9	3.4e-15	0.86	0.07	0.91	FALSE
6	GTEx	Artery Tibial	RP11-443B20.1	0.17	0.08	enet	40	0.09	8.2e-08	7.9	7.4	1.1e-13	0.59	0.40	0.56	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EFR3B	0.03	0.05	lasso	1	0.04	1.9e-05	-7.4	-7.4	1.9e-13	-0.67	0.55	0.06	FALSE
7	GTEx	Cells EBV-transformed lymphocytes	ADCY3	0.25	0.23	enet	10	0.12	9.2e-05	8.5	-7.2	7.4e-13	-0.84	0.03	0.97	FALSE
14	METSIM	Adipose	EFR3B	0.04	0.00	bslmm	357	0.00	9.7e-02	-1.5	-7.0	3.3e-12	-0.37	0.06	0.08	FALSE
16	YFS	Blood	ADCY3	0.07	0.02	bslmm	343	0.04	7.3e-14	9.8	-6.9	6.7e-12	-0.61	0.01	0.99	FALSE
23	The Cancer Genome Atlas	Lung Adenocarcinoma	POMC	0.14	0.04	enet	7	0.08	5.3e-10	-3.0	-6.5	6.2e-11	-0.22	0.38	0.62	FALSE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	POMC	0.11	0.08	enet	7	0.09	1.6e-09	-3.0	-6.4	1.9e-10	-0.24	0.92	0.06	FALSE
4	GTEx	Adipose Subcutaneous	RP11-443B20.1	0.04	0.00	enet	10	0.00	1.2e-01	4.6	6.3	2.2e-10	0.81	0.04	0.90	FALSE
24	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	POMC	0.22	0.05	blup	37	0.03	2.1e-02	-3.9	-6.3	3.0e-10	-0.12	0.01	0.29	FALSE
2	CommonMind	Brain Pre-frontal Cortex	CENPO	0.07	0.03	bslmm	322	0.03	7.0e-05	5.5	-6.3	3.2e-10	-0.49	0.44	0.30	FALSE
22	The Cancer Genome Atlas	Lung Adenocarcinoma	DNAJC27	0.05	0.01	blup	46	0.04	3.2e-05	2.8	-5.7	1.0e-08	-0.55	0.34	0.61	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	POMC	0.08	0.05	lasso	3	0.06	2.6e-12	-3.0	-5.7	1.3e-08	-0.20	0.97	0.03	FALSE
17	YFS	Blood	POMC	0.35	0.05	enet	71	0.19	5.7e-59	-5.6	-5.6	1.8e-08	-0.31	1.00	0.00	FALSE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	POMC	0.06	0.00	enet	12	0.03	9.3e-05	-3.0	-5.5	3.2e-08	-0.27	0.01	0.41	FALSE