Best TWAS P=1.23e-07 · Best GWAS P=1.23e-08 conditioned to 0.000464
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RNF111 | 0.07 | 0.00 | blup | 466 | 0.03 | 0.00016 | 4.3 | 5.3 | 1.2e-07 | 0.51 | 0.34 | 0.22 | TRUE |
| 2 | GTEx | Adipose Subcutaneous | ADAM10 | 0.06 | 0.02 | lasso | 3 | 0.02 | 0.01260 | 5.1 | 5.2 | 1.9e-07 | 0.97 | 0.03 | 0.96 | FALSE |
| 3 | GTEx | Heart Atrial Appendage | ADAM10 | 0.09 | 0.01 | lasso | 2 | 0.01 | 0.17600 | 5.1 | 5.2 | 1.5e-07 | 0.90 | 0.02 | 0.95 | FALSE |