[Hub]/) : Traits : Hip circumference :

chr15:66,998,610-68,789,191

Best TWAS P=1.93e-13 · Best GWAS P=3.49e-15 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous MAP2K5 0.14 0.18 lasso 4 0.18 1.0e-14 -5.6 5.7 1.4e-08 -0.66 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum MAP2K5 0.07 0.08 lasso 3 0.05 1.0e-03 -5.8 6.1 7.8e-10 -0.65 0.08 0.87 FALSE
3 GTEx Artery Aorta MAP2K5 0.06 0.05 enet 6 0.05 7.7e-04 -5.6 6.1 1.3e-09 -0.65 0.35 0.46 FALSE
4 GTEx Artery Tibial MAP2K5 0.15 0.18 lasso 3 0.18 6.3e-14 -5.6 5.7 9.5e-09 -0.66 1.00 0.00 FALSE
5 GTEx Brain Hippocampus IQCH-AS1 0.20 0.08 enet 11 0.05 2.2e-02 4.3 -5.9 3.3e-09 0.74 0.13 0.28 FALSE
6 GTEx Breast Mammary Tissue MAP2K5 0.14 0.07 lasso 5 0.09 2.8e-05 -7.1 6.3 3.1e-10 -0.62 0.07 0.93 FALSE
7 GTEx Esophagus Muscularis MAP2K5 0.24 0.14 lasso 4 0.13 2.1e-08 -5.6 5.7 1.5e-08 -0.65 0.99 0.00 FALSE
8 GTEx Heart Atrial Appendage MAP2K5 0.16 0.08 lasso 5 0.16 1.3e-07 -5.5 6.5 1.1e-10 -0.80 0.09 0.91 FALSE
9 GTEx Heart Left Ventricle MAP2K5 0.10 0.10 lasso 3 0.10 9.4e-06 -5.6 5.7 1.0e-08 -0.66 0.67 0.26 FALSE
10 GTEx Lung MAP2K5 0.12 0.09 enet 11 0.07 3.6e-06 -5.5 5.3 8.8e-08 -0.60 0.93 0.04 FALSE
11 GTEx Muscle Skeletal MAP2K5 0.08 0.03 lasso 6 0.05 1.9e-05 5.5 7.0 1.9e-12 -0.91 0.01 0.99 FALSE
12 GTEx Nerve Tibial MAP2K5 0.19 0.21 lasso 2 0.20 3.3e-14 -5.6 5.6 1.9e-08 -0.66 0.99 0.01 FALSE
13 GTEx Ovary MAP2K5 0.19 0.24 lasso 3 0.21 8.3e-06 -5.6 5.7 1.2e-08 -0.65 0.14 0.68 FALSE
14 GTEx Skin Sun Exposed Lower leg MAP2K5 0.13 0.06 lasso 4 0.09 4.4e-08 4.5 5.7 9.1e-09 -0.73 0.85 0.14 FALSE
15 GTEx Thyroid MAP2K5 0.11 0.16 lasso 4 0.15 9.6e-12 -5.6 6.0 2.4e-09 -0.68 0.95 0.05 FALSE
16 GTEx Whole Blood MAP2K5 0.09 0.06 lasso 6 0.06 8.1e-06 -5.6 6.1 9.4e-10 -0.64 0.71 0.16 FALSE
17 METSIM Adipose MAP2K5 0.07 0.05 enet 19 0.06 2.8e-09 -7.0 6.4 1.3e-10 -0.60 0.09 0.91 FALSE
18 NTR Blood MAP2K5 0.02 0.00 enet 13 0.01 5.7e-04 -5.7 5.3 1.0e-07 -0.60 0.42 0.50 FALSE
19 YFS Blood MAP2K5 0.05 0.07 lasso 4 0.07 1.2e-21 -5.6 5.5 4.8e-08 -0.63 1.00 0.00 FALSE
20 The Cancer Genome Atlas Breast Invasive Carcinoma IQCH 0.06 0.05 blup 112 0.06 5.2e-12 -3.6 5.7 9.8e-09 -0.65 0.96 0.04 FALSE
21 The Cancer Genome Atlas Glioblastoma Multiforme IQCH 0.19 0.14 enet 21 0.12 2.4e-04 -5.2 6.2 5.5e-10 -0.66 0.05 0.91 FALSE
22 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma IQCH 0.06 0.04 blup 111 0.03 1.0e-04 -5.2 5.6 2.6e-08 -0.67 0.06 0.88 FALSE
23 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma IQCH 0.12 0.10 enet 22 0.12 4.0e-13 -5.1 5.6 1.8e-08 -0.61 0.65 0.35 FALSE
24 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MAP2K5 0.03 0.03 blup 142 0.02 1.6e-03 -5.7 6.0 1.6e-09 -0.53 0.10 0.85 TRUE
25 The Cancer Genome Atlas Brain Lower Grade Glioma IQCH 0.05 0.04 blup 111 0.04 7.7e-06 -5.2 5.8 8.1e-09 -0.69 0.07 0.92 FALSE
26 The Cancer Genome Atlas Liver Hepatocellular Carcinoma IQCH 0.10 0.01 blup 111 0.03 1.4e-02 5.1 6.5 9.1e-11 -0.72 0.02 0.70 TRUE
27 The Cancer Genome Atlas Lung Adenocarcinoma IQCH 0.04 0.02 enet 8 0.01 1.6e-02 -6.4 7.4 1.9e-13 -0.71 0.01 0.95 TRUE
28 The Cancer Genome Atlas Lung Adenocarcinoma MAP2K5 0.04 0.04 lasso 3 0.03 8.7e-05 -5.6 5.8 6.2e-09 -0.66 0.15 0.81 FALSE
29 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IQCH 0.04 0.02 enet 6 0.03 1.6e-04 -5.8 6.5 8.4e-11 -0.63 0.11 0.77 TRUE
30 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma IQCH 0.11 0.10 blup 112 0.10 2.3e-07 -6.3 6.1 1.3e-09 -0.71 0.00 1.00 FALSE
31 The Cancer Genome Atlas Pancreatic Adenocarcinoma IQCH 0.35 0.04 blup 112 0.12 1.5e-05 -5.2 6.4 2.0e-10 -0.57 0.34 0.30 FALSE
32 The Cancer Genome Atlas Prostate Adenocarcinoma IQCH 0.19 0.07 blup 111 0.16 7.4e-17 -3.3 5.7 1.0e-08 -0.70 0.03 0.97 FALSE
33 The Cancer Genome Atlas Stomach Adenocarcinoma IQCH 0.08 0.03 blup 111 0.04 9.2e-04 -5.2 5.7 1.3e-08 -0.62 0.07 0.35 FALSE
34 The Cancer Genome Atlas Thyroid Carcinoma IQCH 0.15 0.17 enet 19 0.17 1.3e-16 -5.1 6.0 1.6e-09 -0.67 0.21 0.79 FALSE
35 The Cancer Genome Atlas Thyroid Carcinoma MAP2K5 0.10 0.06 lasso 5 0.04 6.1e-05 -5.7 5.7 1.1e-08 -0.64 0.68 0.28 FALSE