[Hub]/) : Traits : Hip circumference : ← →

chr15:66,998,610-68,789,191

Best TWAS P=1.93e-13 · Best GWAS P=3.49e-15 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
27	The Cancer Genome Atlas	Lung Adenocarcinoma	IQCH	0.04	0.02	enet	8	0.01	1.6e-02	-6.4	7.4	1.9e-13	-0.71	0.01	0.95	TRUE
29	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	IQCH	0.04	0.02	enet	6	0.03	1.6e-04	-5.8	6.5	8.4e-11	-0.63	0.11	0.77	TRUE
26	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	IQCH	0.10	0.01	blup	111	0.03	1.4e-02	5.1	6.5	9.1e-11	-0.72	0.02	0.70	TRUE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MAP2K5	0.03	0.03	blup	142	0.02	1.6e-03	-5.7	6.0	1.6e-09	-0.53	0.10	0.85	TRUE
11	GTEx	Muscle Skeletal	MAP2K5	0.08	0.03	lasso	6	0.05	1.9e-05	5.5	7.0	1.9e-12	-0.91	0.01	0.99	FALSE
8	GTEx	Heart Atrial Appendage	MAP2K5	0.16	0.08	lasso	5	0.16	1.3e-07	-5.5	6.5	1.1e-10	-0.80	0.09	0.91	FALSE
17	METSIM	Adipose	MAP2K5	0.07	0.05	enet	19	0.06	2.8e-09	-7.0	6.4	1.3e-10	-0.60	0.09	0.91	FALSE
31	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	IQCH	0.35	0.04	blup	112	0.12	1.5e-05	-5.2	6.4	2.0e-10	-0.57	0.34	0.30	FALSE
6	GTEx	Breast Mammary Tissue	MAP2K5	0.14	0.07	lasso	5	0.09	2.8e-05	-7.1	6.3	3.1e-10	-0.62	0.07	0.93	FALSE
21	The Cancer Genome Atlas	Glioblastoma Multiforme	IQCH	0.19	0.14	enet	21	0.12	2.4e-04	-5.2	6.2	5.5e-10	-0.66	0.05	0.91	FALSE
2	GTEx	Adipose Visceral Omentum	MAP2K5	0.07	0.08	lasso	3	0.05	1.0e-03	-5.8	6.1	7.8e-10	-0.65	0.08	0.87	FALSE
16	GTEx	Whole Blood	MAP2K5	0.09	0.06	lasso	6	0.06	8.1e-06	-5.6	6.1	9.4e-10	-0.64	0.71	0.16	FALSE
3	GTEx	Artery Aorta	MAP2K5	0.06	0.05	enet	6	0.05	7.7e-04	-5.6	6.1	1.3e-09	-0.65	0.35	0.46	FALSE
30	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	IQCH	0.11	0.10	blup	112	0.10	2.3e-07	-6.3	6.1	1.3e-09	-0.71	0.00	1.00	FALSE
34	The Cancer Genome Atlas	Thyroid Carcinoma	IQCH	0.15	0.17	enet	19	0.17	1.3e-16	-5.1	6.0	1.6e-09	-0.67	0.21	0.79	FALSE
15	GTEx	Thyroid	MAP2K5	0.11	0.16	lasso	4	0.15	9.6e-12	-5.6	6.0	2.4e-09	-0.68	0.95	0.05	FALSE
5	GTEx	Brain Hippocampus	IQCH-AS1	0.20	0.08	enet	11	0.05	2.2e-02	4.3	-5.9	3.3e-09	0.74	0.13	0.28	FALSE
28	The Cancer Genome Atlas	Lung Adenocarcinoma	MAP2K5	0.04	0.04	lasso	3	0.03	8.7e-05	-5.6	5.8	6.2e-09	-0.66	0.15	0.81	FALSE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	IQCH	0.05	0.04	blup	111	0.04	7.7e-06	-5.2	5.8	8.1e-09	-0.69	0.07	0.92	FALSE
14	GTEx	Skin Sun Exposed Lower leg	MAP2K5	0.13	0.06	lasso	4	0.09	4.4e-08	4.5	5.7	9.1e-09	-0.73	0.85	0.14	FALSE
4	GTEx	Artery Tibial	MAP2K5	0.15	0.18	lasso	3	0.18	6.3e-14	-5.6	5.7	9.5e-09	-0.66	1.00	0.00	FALSE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	IQCH	0.06	0.05	blup	112	0.06	5.2e-12	-3.6	5.7	9.8e-09	-0.65	0.96	0.04	FALSE
9	GTEx	Heart Left Ventricle	MAP2K5	0.10	0.10	lasso	3	0.10	9.4e-06	-5.6	5.7	1.0e-08	-0.66	0.67	0.26	FALSE
32	The Cancer Genome Atlas	Prostate Adenocarcinoma	IQCH	0.19	0.07	blup	111	0.16	7.4e-17	-3.3	5.7	1.0e-08	-0.70	0.03	0.97	FALSE
35	The Cancer Genome Atlas	Thyroid Carcinoma	MAP2K5	0.10	0.06	lasso	5	0.04	6.1e-05	-5.7	5.7	1.1e-08	-0.64	0.68	0.28	FALSE
13	GTEx	Ovary	MAP2K5	0.19	0.24	lasso	3	0.21	8.3e-06	-5.6	5.7	1.2e-08	-0.65	0.14	0.68	FALSE
33	The Cancer Genome Atlas	Stomach Adenocarcinoma	IQCH	0.08	0.03	blup	111	0.04	9.2e-04	-5.2	5.7	1.3e-08	-0.62	0.07	0.35	FALSE
1	GTEx	Adipose Subcutaneous	MAP2K5	0.14	0.18	lasso	4	0.18	1.0e-14	-5.6	5.7	1.4e-08	-0.66	1.00	0.00	FALSE
7	GTEx	Esophagus Muscularis	MAP2K5	0.24	0.14	lasso	4	0.13	2.1e-08	-5.6	5.7	1.5e-08	-0.65	0.99	0.00	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IQCH	0.12	0.10	enet	22	0.12	4.0e-13	-5.1	5.6	1.8e-08	-0.61	0.65	0.35	FALSE
12	GTEx	Nerve Tibial	MAP2K5	0.19	0.21	lasso	2	0.20	3.3e-14	-5.6	5.6	1.9e-08	-0.66	0.99	0.01	FALSE
22	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	IQCH	0.06	0.04	blup	111	0.03	1.0e-04	-5.2	5.6	2.6e-08	-0.67	0.06	0.88	FALSE
19	YFS	Blood	MAP2K5	0.05	0.07	lasso	4	0.07	1.2e-21	-5.6	5.5	4.8e-08	-0.63	1.00	0.00	FALSE
10	GTEx	Lung	MAP2K5	0.12	0.09	enet	11	0.07	3.6e-06	-5.5	5.3	8.8e-08	-0.60	0.93	0.04	FALSE
18	NTR	Blood	MAP2K5	0.02	0.00	enet	13	0.01	5.7e-04	-5.7	5.3	1.0e-07	-0.60	0.42	0.50	FALSE