Best TWAS P=5.22e-09 · Best GWAS P=5.51e-13 conditioned to 7.51e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CADM2 | 0.06 | 0.00 | blup | 339 | 0.00 | 2.7e-01 | -5.0 | -5.4 | 7.5e-08 | 0.75 | 0.02 | 0.77 | FALSE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | CADM2 | 0.08 | 0.04 | lasso | 4 | 0.05 | 2.1e-06 | 5.1 | 5.8 | 5.2e-09 | -0.66 | 0.71 | 0.28 | TRUE |
3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CADM2 | 0.05 | 0.03 | lasso | 3 | 0.04 | 5.0e-05 | 5.1 | 5.6 | 2.2e-08 | -0.59 | 0.88 | 0.06 | FALSE |