Best TWAS P=3.18e-10 · Best GWAS P=3.15e-10 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | C3orf38 | 0.08 | 0.00 | enet | 14 | 0.04 | 2.3e-05 | -4.9 | -5.5 | 3.1e-08 | 0.63 | 0.04 | 0.92 | FALSE |
2 | GTEx | Cells Transformed fibroblasts | ZNF654 | 0.08 | 0.09 | enet | 6 | 0.10 | 3.1e-08 | -6.3 | -6.3 | 3.2e-10 | 0.99 | 0.00 | 1.00 | TRUE |
3 | GTEx | Esophagus Mucosa | C3orf38 | 0.11 | 0.06 | lasso | 7 | 0.07 | 1.5e-05 | -5.0 | 5.7 | 1.5e-08 | -0.91 | 0.08 | 0.92 | FALSE |