Best TWAS P=1.28e-11 · Best GWAS P=9.61e-22 conditioned to 4.21e-16
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | EPDR1 | 0.24 | 0.11 | lasso | 10 | 0.12 | 2.4e-14 | 4.1 | 6.0 | 1.8e-09 | -0.11 | 1.00 | 0.00 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | EPDR1 | 0.17 | 0.06 | lasso | 6 | 0.10 | 2.5e-13 | 2.9 | 5.8 | 8.0e-09 | -0.07 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | EPDR1 | 0.06 | 0.01 | enet | 22 | 0.06 | 6.7e-12 | 4.3 | 6.8 | 1.3e-11 | -0.25 | 0.95 | 0.00 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | EPDR1 | 0.08 | 0.04 | enet | 3 | 0.05 | 5.4e-06 | 4.0 | 5.2 | 1.6e-07 | -0.25 | 0.86 | 0.01 | FALSE |
| 5 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | EPDR1 | 0.09 | 0.10 | lasso | 2 | 0.06 | 2.8e-03 | -5.4 | 5.7 | 1.3e-08 | -0.15 | 0.09 | 0.06 | FALSE |