Best TWAS P=4.3e-12 · Best GWAS P=6.42e-26 conditioned to 3.27e-16
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Atrial Appendage | SEPT7P2 | 0.15 | 0 | lasso | 9 | 0.08 | 1.8e-04 | -5.5 | -5.8 | 6.6e-09 | -0.05 | 0.20 | 0.06 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | IGFBP3 | 0.09 | 0 | lasso | 6 | 0.00 | 2.7e-01 | -6.3 | -6.9 | 4.3e-12 | -0.27 | 0.15 | 0.03 | TRUE |
| 3 | NTR | Blood | IGFBP3 | 0.03 | 0 | bslmm | 413 | 0.01 | 1.1e-05 | 2.4 | 5.5 | 3.7e-08 | 0.10 | 0.16 | 0.03 | TRUE |