Best TWAS P=4.77e-09 · Best GWAS P=2.07e-10 conditioned to 5.37e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LOC100506990 | 0.08 | 0.03 | enet | 32 | 0.05 | 4.1e-07 | -4.6 | -5.9 | 4.8e-09 | -0.03 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Artery Tibial | AF131215.2 | 0.07 | 0.03 | enet | 24 | 0.05 | 1.8e-04 | 2.3 | -5.5 | 4.0e-08 | 0.02 | 0.13 | 0.81 | FALSE |
| 3 | GTEx | Breast Mammary Tissue | AF131215.9 | 0.10 | 0.10 | lasso | 8 | 0.12 | 8.7e-07 | 4.9 | -5.2 | 1.9e-07 | -0.03 | 0.05 | 0.94 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | FAM85A | 0.11 | 0.07 | enet | 23 | 0.11 | 4.3e-14 | -2.7 | -5.2 | 2.3e-07 | -0.06 | 0.01 | 0.99 | FALSE |