TWAS
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Traits
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Traits
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Standing height
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chr8:75,200,357-76,644,573
Best TWAS P=4.32e-18 · Best GWAS P=7.98e-25 conditioned to 0.000172
75.2M
75.4M
75.6M
75.8M
76M
76.2M
76.4M
76.6M
0
5
10
15
20
25
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
METSIM
Adipose
CRISPLD1
0.04
0.01
lasso
4
0.02
0.0016
10.3
8.7
4.3e-18
0.82
0.00
0.99
TRUE
2
The Cancer Genome Atlas
Colon Adenocarcinoma
CRISPLD1
0.10
0.02
enet
11
0.01
0.0921
2.3
-6.3
3.9e-10
-0.18
0.02
0.09
TRUE