Best TWAS P=4.32e-18 · Best GWAS P=7.98e-25 conditioned to 0.000172
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | CRISPLD1 | 0.04 | 0.01 | lasso | 4 | 0.02 | 0.0016 | 10.3 | 8.7 | 4.3e-18 | 0.82 | 0.00 | 0.99 | TRUE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | CRISPLD1 | 0.10 | 0.02 | enet | 11 | 0.01 | 0.0921 | 2.3 | -6.3 | 3.9e-10 | -0.18 | 0.02 | 0.09 | TRUE |