Best TWAS P=7.63e-11 · Best GWAS P=1.11e-09 conditioned to 1.21e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TXN | 0.12 | 0.10 | lasso | 4 | 0.15 | 8.4e-18 | -5.3 | 6.5 | 7.6e-11 | 0.00 | 0.01 | 0.99 | TRUE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TXN | 0.06 | 0.04 | enet | 8 | 0.03 | 7.7e-05 | -5.7 | 6.4 | 1.9e-10 | 0.01 | 0.00 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | TXN | 0.17 | 0.11 | lasso | 3 | 0.12 | 5.4e-12 | -5.7 | 5.4 | 7.1e-08 | 0.01 | 0.00 | 1.00 | FALSE |