Best TWAS P=1.08e-09 · Best GWAS P=7.97e-09 conditioned to 0.168
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | BET1L | 0.12 | 0.08 | lasso | 2 | 0.07 | 7.3e-06 | -5.8 | -5.9 | 2.9e-09 | 0.99 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Breast Mammary Tissue | BET1L | 0.15 | 0.09 | lasso | 5 | 0.04 | 2.3e-03 | -5.8 | -5.8 | 7.1e-09 | 1.00 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Breast Mammary Tissue (Female) | BET1L | 0.11 | 0.04 | lasso | 2 | 0.01 | 1.9e-01 | -5.8 | -6.1 | 1.1e-09 | 0.81 | 0.01 | 0.66 | TRUE |
| 4 | GTEx | Esophagus Mucosa | BET1L | 0.21 | 0.12 | lasso | 2 | 0.13 | 4.8e-09 | -5.8 | -6.1 | 1.1e-09 | 0.94 | 0.00 | 1.00 | FALSE |
| 5 | GTEx | Skin Sun Exposed Lower leg | BET1L | 0.16 | 0.17 | enet | 7 | 0.16 | 5.3e-13 | -5.8 | -5.5 | 3.0e-08 | 0.97 | 0.00 | 1.00 | FALSE |
| 6 | METSIM | Adipose | BET1L | 0.08 | 0.02 | lasso | 9 | 0.01 | 2.5e-03 | -5.8 | -5.2 | 1.7e-07 | 0.93 | 0.00 | 1.00 | FALSE |