Best TWAS P=1.14e-10 · Best GWAS P=3.32e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | TRIM66 | 0.54 | 0.34 | enet | 46 | 0.43 | 4.2e-16 | 3.7 | 6.5 | 1.1e-10 | 0.06 | 0.68 | 0.18 | TRUE |
| 2 | GTEx | Brain Cortex | RP11-152H18.3 | 0.41 | 0.04 | enet | 25 | 0.11 | 7.6e-04 | 3.7 | -5.2 | 2.5e-07 | -0.07 | 0.09 | 0.20 | FALSE |
| 3 | GTEx | Prostate | SBF2 | 0.21 | 0.05 | lasso | 7 | 0.03 | 6.7e-02 | 5.6 | 5.2 | 1.6e-07 | 0.94 | 0.07 | 0.61 | FALSE |
| 4 | GTEx | Testis | SBF2 | 0.10 | 0.01 | lasso | 5 | 0.02 | 5.0e-02 | 5.8 | -5.7 | 1.6e-08 | -0.98 | 0.05 | 0.86 | TRUE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | SBF2-AS1 | 0.03 | 0.00 | bslmm | 362 | 0.01 | 4.4e-03 | -1.4 | 5.5 | 4.2e-08 | 0.61 | 0.05 | 0.53 | FALSE |
| 6 | YFS | Blood | ADM | 0.08 | 0.11 | enet | 25 | 0.12 | 9.4e-36 | 5.7 | -5.2 | 2.0e-07 | -0.92 | 0.02 | 0.98 | FALSE |
| 7 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ZNF143 | 0.02 | 0.02 | lasso | 2 | 0.02 | 4.5e-03 | 5.4 | -5.4 | 7.3e-08 | -0.05 | 0.01 | 0.87 | TRUE |