Best TWAS P=3.74e-09 · Best GWAS P=6.33e-12 conditioned to 0.000389
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SUGT1L1 | 0.09 | 0.06 | lasso | 7 | 0.09 | 8.4e-18 | 3.3 | -5.4 | 6.5e-08 | 0.81 | 0.01 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SUGT1L1 | 0.29 | 0.23 | lasso | 8 | 0.25 | 1.7e-28 | 3.4 | -5.3 | 1.1e-07 | 0.79 | 0.98 | 0.02 | FALSE |
| 3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | SUGT1L1 | 0.22 | 0.07 | lasso | 11 | 0.13 | 9.4e-06 | -6.7 | -5.9 | 3.7e-09 | 0.88 | 0.01 | 0.96 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SUGT1L1 | 0.21 | 0.11 | lasso | 9 | 0.16 | 5.7e-16 | 3.4 | -5.6 | 2.3e-08 | 0.84 | 0.02 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Stomach Adenocarcinoma | SUGT1L1 | 0.09 | 0.06 | blup | 59 | 0.06 | 5.4e-05 | -6.7 | -5.6 | 2.8e-08 | 0.85 | 0.00 | 1.00 | FALSE |