Best TWAS P=5.97e-09 · Best GWAS P=3.61e-10 conditioned to 0.0406
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | COG6 | 0.10 | 0.07 | lasso | 4 | 0.08 | 7.0e-08 | 4.8 | -5.5 | 3.7e-08 | 0.09 | 0.25 | 0.74 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | STOML3 | 0.03 | 0.01 | blup | 75 | 0.02 | 6.6e-03 | -6.1 | 5.8 | 6.0e-09 | -0.81 | 0.01 | 0.93 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | STOML3 | 0.03 | 0.01 | lasso | 3 | 0.02 | 6.6e-03 | -5.7 | 5.8 | 7.7e-09 | -0.90 | 0.01 | 0.87 | FALSE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | COG6 | 0.05 | 0.00 | blup | 99 | 0.02 | 8.2e-03 | -4.1 | -5.6 | 2.6e-08 | 0.06 | 0.04 | 0.12 | TRUE |