Best TWAS P=3.23e-08 · Best GWAS P=1.26e-09 conditioned to 1.9e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Putamen basal ganglia | WWOX | 0.57 | 0.04 | enet | 23 | 0.01 | 1.6e-01 | -4.6 | -5.5 | 3.2e-08 | 0.01 | 0.18 | 0.06 | TRUE |
| 2 | GTEx | Liver | WWOX | 0.49 | 0.00 | enet | 16 | 0.02 | 8.2e-02 | 4.9 | -5.2 | 2.2e-07 | 0.26 | 0.18 | 0.17 | FALSE |
| 3 | GTEx | Lung | WWOX | 0.33 | 0.07 | lasso | 11 | 0.10 | 5.7e-08 | 3.5 | -5.5 | 4.4e-08 | 0.25 | 0.88 | 0.05 | TRUE |
| 4 | GTEx | Nerve Tibial | WWOX | 0.55 | 0.23 | lasso | 15 | 0.28 | 5.6e-20 | -4.0 | -5.5 | 4.7e-08 | 0.18 | 0.97 | 0.02 | FALSE |