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chr16:74,485,529-76,197,034

Best TWAS P=1.26e-12 · Best GWAS P=1.38e-12 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Breast Mammary Tissue	ZFP1	0.21	0.18	lasso	2	0.17	7.0e-09	-6.9	7.1	1.3e-12	-0.95	0.00	1.00	TRUE
29	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TMEM170A	0.08	0.10	blup	36	0.13	9.1e-08	-4.2	-6.1	1.2e-09	0.06	0.01	0.99	TRUE
21	GTEx	Testis	ZFP1	0.17	0.14	lasso	3	0.12	4.5e-06	-7.1	7.1	1.3e-12	-0.99	0.00	1.00	FALSE
24	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZFP1	0.08	0.10	lasso	3	0.10	2.5e-20	-6.8	7.0	2.9e-12	-0.97	0.00	1.00	FALSE
2	GTEx	Adipose Visceral Omentum	ZFP1	0.38	0.21	lasso	5	0.21	5.6e-11	-6.9	6.9	5.3e-12	-0.94	0.00	1.00	FALSE
14	GTEx	Heart Atrial Appendage	ZFP1	0.23	0.15	lasso	2	0.14	9.1e-07	-6.9	6.9	6.2e-12	-0.97	0.00	0.99	FALSE
4	GTEx	Adrenal Gland	ZFP1	0.53	0.28	enet	30	0.30	1.7e-11	-6.9	6.8	1.0e-11	-0.82	0.00	1.00	FALSE
6	GTEx	Artery Aorta	ZFP1	0.28	0.14	enet	13	0.19	1.0e-10	-6.8	6.7	1.9e-11	-0.90	0.00	1.00	FALSE
22	GTEx	Thyroid	ZFP1	0.27	0.16	enet	17	0.18	1.3e-13	-6.9	6.7	2.6e-11	-0.92	0.00	1.00	FALSE
31	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZFP1	0.15	0.12	lasso	6	0.13	2.7e-14	-6.5	6.6	3.2e-11	-0.86	0.06	0.94	FALSE
15	GTEx	Heart Left Ventricle	ZFP1	0.37	0.20	lasso	8	0.19	1.4e-10	-6.8	6.5	7.6e-11	-0.90	0.00	1.00	FALSE
26	The Cancer Genome Atlas	Esophageal Carcinoma	ZFP1	0.19	0.01	blup	63	0.06	6.9e-03	-4.7	6.4	1.2e-10	-0.58	0.01	0.54	FALSE
19	GTEx	Skin Not Sun Exposed Suprapubic	ZFP1	0.33	0.15	lasso	10	0.16	2.8e-09	-6.8	6.3	2.3e-10	-0.94	0.00	1.00	FALSE
9	GTEx	Breast Mammary Tissue (Male)	ZFP1	0.23	0.24	lasso	3	0.22	7.8e-06	-6.3	6.3	3.3e-10	-0.79	0.02	0.90	FALSE
34	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZFP1	0.10	0.09	blup	63	0.08	2.2e-08	-6.9	6.1	1.4e-09	-0.88	0.00	1.00	FALSE
20	GTEx	Skin Sun Exposed Lower leg	CFDP1	0.17	0.13	enet	25	0.11	2.8e-09	-4.9	-6.0	1.5e-09	0.11	1.00	0.00	FALSE
25	The Cancer Genome Atlas	Colon Adenocarcinoma	ZFP1	0.22	0.09	lasso	6	0.12	3.3e-07	-6.8	6.0	1.6e-09	-0.84	0.01	0.99	FALSE
33	The Cancer Genome Atlas	Lung Adenocarcinoma	ZFP1	0.20	0.07	enet	11	0.14	1.3e-16	-6.9	6.0	2.1e-09	-0.83	0.00	1.00	FALSE
18	GTEx	Nerve Tibial	ZFP1	0.41	0.23	enet	17	0.25	8.6e-18	-6.9	6.0	2.7e-09	-0.92	0.00	1.00	FALSE
36	The Cancer Genome Atlas	Thyroid Carcinoma	ZFP1	0.25	0.16	blup	63	0.16	1.5e-15	-6.9	5.8	6.4e-09	-0.78	0.00	1.00	FALSE
27	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CFDP1	0.02	0.02	lasso	4	0.02	1.9e-03	-5.8	-5.8	7.5e-09	0.02	0.02	0.92	FALSE
1	GTEx	Adipose Visceral Omentum	CFDP1	0.20	0.09	lasso	4	0.08	5.2e-05	-4.4	-5.7	1.4e-08	0.08	0.55	0.02	FALSE
16	GTEx	Muscle Skeletal	ZFP1	0.27	0.08	enet	31	0.11	3.1e-11	-6.9	5.7	1.4e-08	-0.80	0.00	1.00	FALSE
5	GTEx	Artery Aorta	BCAR1	0.18	0.13	lasso	3	0.11	9.8e-07	-5.5	5.7	1.5e-08	-0.06	0.98	0.02	FALSE
10	GTEx	Cells Transformed fibroblasts	CFDP1	0.17	0.20	enet	10	0.24	9.9e-18	-5.4	-5.7	1.5e-08	0.04	0.98	0.02	FALSE
12	GTEx	Esophagus Gastroesophageal Junction	ZFP1	0.35	0.16	lasso	3	0.14	7.7e-06	-6.9	5.6	1.8e-08	-0.92	0.00	0.99	FALSE
28	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ZFP1	0.21	0.12	lasso	5	0.18	2.1e-20	-6.8	5.6	1.8e-08	-0.86	0.00	1.00	FALSE
23	The Cancer Genome Atlas	Breast Invasive Carcinoma	CFDP1	0.04	0.03	enet	10	0.03	5.2e-07	-4.9	-5.6	2.6e-08	-0.03	0.26	0.73	FALSE
37	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	ZFP1	0.32	-0.01	blup	63	0.01	1.6e-01	-6.5	5.5	3.3e-08	-0.75	0.01	0.59	FALSE
13	GTEx	Esophagus Muscularis	ZFP1	0.30	0.23	lasso	4	0.26	3.8e-16	-6.9	5.4	5.3e-08	-0.91	0.00	1.00	FALSE
3	GTEx	Adrenal Gland	TMEM170A	0.11	0.06	enet	4	0.04	1.7e-02	-5.5	5.4	5.5e-08	-0.08	0.27	0.05	FALSE
35	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CHST6	0.20	0.08	enet	10	0.10	2.2e-04	-4.8	5.4	5.6e-08	-0.14	0.01	0.92	FALSE
17	GTEx	Nerve Tibial	CFDP1	0.16	0.14	lasso	3	0.12	1.6e-08	-4.9	-5.4	5.7e-08	-0.01	1.00	0.00	FALSE
30	The Cancer Genome Atlas	Brain Lower Grade Glioma	CFDP1	0.04	0.02	lasso	6	0.03	4.0e-04	-4.4	-5.3	9.0e-08	0.00	0.03	0.96	FALSE
7	GTEx	Brain Cortex	CFDP1	0.18	0.07	lasso	3	0.08	3.4e-03	-4.8	-5.3	1.4e-07	-0.02	0.16	0.05	FALSE
32	The Cancer Genome Atlas	Lung Adenocarcinoma	CFDP1	0.05	0.02	enet	11	0.04	2.0e-05	-5.1	-5.3	1.4e-07	-0.05	0.20	0.41	FALSE
11	GTEx	Esophagus Gastroesophageal Junction	CFDP1	0.31	0.17	lasso	4	0.16	3.0e-06	-5.1	-5.2	1.7e-07	-0.04	0.89	0.01	FALSE