Best TWAS P=1.62e-15 · Best GWAS P=3.67e-17 conditioned to 0.0015
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CADM2 | 0.06 | 0.00 | blup | 339 | 0.00 | 2.7e-01 | 4.8 | 8.0 | 1.6e-15 | 0.75 | 0.02 | 0.75 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | CADM2 | 0.08 | 0.04 | lasso | 4 | 0.05 | 2.1e-06 | -4.0 | -5.5 | 2.8e-08 | -0.66 | 0.76 | 0.23 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | CADM2 | 0.05 | 0.00 | blup | 339 | 0.02 | 3.2e-03 | -5.5 | -7.8 | 6.8e-15 | -0.53 | 0.07 | 0.29 | TRUE |