Hub : Traits :

Qualifications: College or University degree

1887 significantly associated models · 344 unique genes.

Significant Loci

#	chr	p0	p1	# assoc genes	# joint genes	best TWAS P	best SNP P	cond SNP P	% var exp	joint genes
1	1	40799427	42542658	2	1	1.2e-12	3.0e-11	3.8e-05	62	FOXO6
2	1	43042125	45157738	14	10	3.0e-15	2.9e-20	NaN	NaN	ARTN CCDC24 HYI ST3GAL3
3	1	45423943	46809419	1	1	2.8e-07	3.9e-06	2.6e-01	94	RP11-767N6.2
4	1	71163715	73435171	1	1	1.7e-23	2.1e-16	3.2e-01	98	NEGR1
5	1	73798439	75701824	5	2	2.1e-11	5.0e-10	3.4e-04	67	FPGT TNNI3K
6	1	92924057	94534354	5	1	1.7e-17	5.7e-18	1.0e+00	100	TMED5
7	1	109316076	110742615	4	1	1.2e-09	5.5e-09	1.5e-08	6	SYPL2
8	1	150282784	151701345	1	1	5.7e-08	8.9e-05	2.0e-03	38	PRUNE
9	1	173437024	175663031	1	1	2.0e-07	2.1e-07	2.7e-01	96	RABGAP1L
10	1	183961643	185416670	1	1	1.2e-07	1.1e-07	1.0e+00	100	EDEM3
11	1	201616627	202161644	1	1	1.2e-07	3.8e-07	8.8e-02	89	LMOD1
12	1	203692179	205241659	2	1	3.9e-09	1.6e-13	8.7e-06	64	MDM4
13	1	234832199	236307360	2	1	8.6e-09	4.6e-09	1.0e+00	100	TBCE
14	1	242590540	244359621	3	1	3.2e-12	3.2e-12	1.0e+00	100	RP11-261C10.5
15	2	43899918	45698128	2	1	1.4e-09	1.5e-08	4.9e-03	75	CAMKMT
16	2	48072855	49519654	1	1	2.0e-07	8.2e-08	4.7e-03	72	STON1
17	2	72787254	74187703	1	1	2.7e-07	2.9e-07	1.3e-05	28	FBXO41
18	2	99468341	101731705	3	3	2.0e-16	1.1e-20	6.7e-02	96	AFF3 LONRF2
19	2	106725928	108199394	1	1	1.7e-07	3.4e-07	1.0e+00	100	ST6GAL2
20	2	159066022	159785940	1	1	1.2e-07	2.0e-09	3.1e-06	40	PKP4
21	2	160879651	162798581	3	2	2.9e-17	1.9e-16	1.0e+00	100	RBMS1 TANK
22	2	233047291	234434621	2	1	5.6e-08	5.1e-07	1.5e-01	92	C2orf82
23	3	47204518	51077419	49	8	3.0e-40	4.6e-34	NaN	NaN	GPX1 MAP4 MST1R NAT6 RBM6 RNF123 TRAIP
24	3	70757099	71880670	1	1	7.1e-09	4.5e-15	3.7e-08	51	FOXP1
25	3	84767271	86367480	1	2	1.6e-15	3.7e-17	1.5e-03	86	CADM2
26	3	107181540	108633112	1	1	5.3e-09	1.0e-08	2.5e-02	85	IFT57
27	4	1947324	3943984	10	1	7.2e-15	1.0e-13	2.9e-01	98	GRK4
28	4	17104059	18507692	1	1	2.6e-07	1.1e-07	1.5e-02	79	DCAF16
29	4	105598022	107092169	1	1	2.4e-13	1.6e-15	3.6e-06	66	PPA2
30	4	151637154	153373680	2	1	2.2e-09	2.8e-11	2.5e-06	50	FAM160A1
31	5	59028853	61156570	8	3	6.8e-19	5.5e-19	4.4e-03	90	ELOVL7 GNL3LP1 PART1
32	5	87006055	88677293	3	2	2.3e-10	7.6e-16	1.9e-04	79	CTC-498M16.2 LINC00461
33	5	92051598	93618113	1	1	8.4e-08	3.3e-08	1.6e-06	25	NR2F1-AS1
34	5	108341478	109898183	1	1	8.0e-09	3.0e-08	1.6e-01	94	MAN2A1
35	5	111615346	113051271	1	1	2.6e-08	2.8e-07	1.6e-01	93	DCP2
36	6	25266147	26682323	1	1	1.2e-07	1.3e-17	6.6e-14	23	TRIM38
37	6	87358929	88997402	3	1	2.7e-10	1.5e-08	1.1e-01	92	SLC35A1
38	6	108183628	109704062	1	1	6.4e-10	1.3e-08	2.6e-01	96	FOXO3
39	7	1580921	2977732	1	1	2.3e-07	2.0e-12	3.3e-08	38	FTSJ2
40	7	20885792	22639717	1	1	2.4e-10	4.7e-10	9.0e-04	72	DNAH11
41	7	23913624	25432157	1	1	7.0e-08	2.5e-08	8.0e-02	90	MPP6
42	7	70354372	72313144	2	2	1.5e-10	1.9e-10	4.7e-02	90	CALN1 WBSCR17
43	7	75059331	75842792	2	1	2.7e-07	2.3e-07	1.0e+00	100	TRIM73
44	7	99260092	100696616	2	1	9.4e-10	4.3e-06	7.4e-01	100	STAG3L5P-PVRIG2P-PILRB
45	8	29996824	31433801	1	1	1.9e-08	1.8e-09	2.2e-02	86	TEX15
46	8	65740418	67170378	2	1	1.2e-07	1.3e-08	3.3e-02	86	CTD-3025N20.2
47	8	86841229	88271452	2	1	9.9e-11	4.0e-07	1.1e-04	42	CPNE3
48	8	118563271	119371015	1	1	1.8e-07	4.6e-09	5.7e-07	27	EXT1
49	8	140969818	142706843	2	2	4.0e-10	2.6e-12	1.4e-10	16	EIF2C2 PTK2
50	8	142839492	144515639	5	1	1.8e-11	8.9e-09	3.1e-02	86	THEM6
51	8	144975935	146293414	4	1	8.7e-09	7.4e-08	8.8e-01	100	CYHR1
52	9	111532820	112121763	1	1	2.0e-07	1.1e-07	1.0e+00	100	C9orf5
53	9	134778255	136238509	1	1	6.6e-10	4.0e-08	5.3e-07	16	DDX31
54	10	10349662	12076043	1	1	7.1e-11	1.3e-11	2.5e-04	71	CELF2
55	10	64195778	65911294	4	1	7.1e-11	3.4e-08	8.1e-04	63	JMJD1C-AS1
56	10	68946505	70532990	2	1	8.9e-10	2.2e-09	8.2e-03	80	HERC4
57	10	102853189	104956035	4	2	4.1e-13	4.5e-13	2.5e-01	98	ACTR1A NPM3
58	10	111062431	112588355	1	1	1.8e-07	1.4e-07	1.0e+00	100	ADD3
59	10	125739009	127174440	1	1	3.3e-09	7.7e-08	6.3e-01	99	METTL10
60	10	133048749	134482926	2	2	2.1e-09	3.0e-13	1.7e-01	96	BNIP3 PPP2R2D
61	11	62126494	62688269	2	1	6.4e-08	3.2e-07	2.2e-04	48	C11orf83
62	11	63389016	64780509	1	1	3.1e-07	8.5e-06	1.7e-01	90	PRDX5
63	11	65353906	67192555	10	2	5.0e-12	5.5e-12	6.6e-02	93	B3GNT1 SNX32
64	11	87146898	88606591	1	1	5.9e-08	3.6e-07	5.5e-02	86	RAB38
65	11	89354278	90716657	1	1	5.2e-08	2.4e-08	4.6e-02	87	RP11-121L10.3
66	11	94805896	96276010	4	1	1.5e-14	3.3e-12	3.3e-01	98	CEP57
67	11	101404645	102797829	1	1	1.7e-07	1.7e-07	1.0e+00	100	RP11-864G5.3
68	11	122897730	124309814	1	1	1.0e-09	6.1e-07	1.1e-03	57	ZNF202
69	12	55677395	57125879	5	1	1.8e-11	3.3e-11	1.0e+00	100	RPS26
70	12	120636549	121146219	1	1	2.6e-07	8.4e-06	9.3e-01	100	GATC
71	12	122258047	124715313	13	1	1.1e-11	7.4e-12	3.4e-02	90	MPHOSPH9
72	13	31078511	32595740	1	1	8.6e-10	9.3e-09	1.9e-02	83	B3GALTL
73	13	98109395	99925872	3	1	5.4e-10	8.0e-08	8.0e-01	100	STK24
74	13	100487469	101940873	1	1	1.9e-07	1.0e-08	3.5e-04	61	GGACT
75	14	22670975	24125886	3	1	6.1e-08	5.3e-08	1.0e+00	100	RP11-298I3.1
76	14	26213713	27761335	1	1	1.7e-08	5.6e-14	2.6e-07	53	NOVA1
77	14	69027866	70518587	2	1	2.2e-10	3.5e-09	1.7e-02	84	GALNT16
78	14	71712035	73729498	1	1	5.5e-08	7.7e-09	5.3e-05	51	RGS6
79	14	103325757	104892153	7	1	2.0e-11	2.3e-11	4.5e-02	91	TRMT61A
80	15	46780520	48764942	1	1	1.9e-07	3.2e-12	2.4e-08	36	SEMA6D
81	15	81734963	82581264	1	1	1.4e-07	5.9e-06	1.1e-01	88	EFTUD1
82	16	86671	1962132	9	2	1.7e-09	1.3e-09	1.5e-04	61	CACNA1H WDR24
83	16	11326785	12915579	2	2	2.0e-08	1.1e-07	1.7e-01	93	RP11-166B2.1 SNX29
84	16	14323446	15921958	2	1	6.7e-08	2.9e-06	5.7e-01	98	RP11-1186N24.5
85	16	27412414	30703155	24	2	3.4e-14	8.6e-13	1.8e-01	96	EIF3CL INO80E
86	16	52772129	54235440	2	1	9.3e-11	3.0e-11	7.5e-02	93	RBL2
87	16	71070698	72657531	3	1	1.6e-09	2.6e-07	8.5e-01	100	IST1
88	17	17747289	18923818	1	1	3.4e-10	1.7e-06	2.7e-01	95	CCDC144B
89	17	29028281	30556282	1	1	2.2e-07	7.3e-07	1.5e-01	91	RAB11FIP4
90	17	37125922	38512197	1	1	8.8e-08	1.7e-05	1.3e-01	88	TCAP
91	17	42774693	45796313	20	1	2.4e-13	2.8e-11	9.4e-01	100	DND1
92	18	20393480	21863589	2	1	5.3e-09	1.2e-08	1.0e+00	100	C18orf8
93	18	34614002	35378540	1	1	2.8e-11	6.0e-25	1.8e-15	40	CELF4
94	19	1473344	2923263	1	1	9.5e-08	6.6e-06	5.0e-04	40	DOT1L
95	19	17562969	19237273	6	2	2.4e-10	3.4e-10	7.9e-02	92	IL12RB1 JUND
96	19	32209988	33668090	1	1	1.2e-07	8.1e-09	2.1e-02	84	DPY19L3
97	19	35448803	36956110	4	1	5.0e-08	1.4e-07	4.3e-01	98	COX6B1
98	19	45064435	46506809	2	1	1.7e-14	1.5e-14	1.0e+00	100	CKM
99	20	2390880	3850968	3	1	1.1e-09	5.5e-08	9.1e-01	100	FASTKD5
100	20	32865844	34556216	3	1	4.6e-09	2.2e-08	3.3e-01	97	PROCR
101	20	42924921	44408428	1	1	3.1e-12	3.8e-13	1.0e+00	100	STK4
102	20	57934675	59346576	1	1	4.1e-08	6.7e-09	8.7e-08	15	C20orf197
103	22	29485708	30932673	1	1	1.3e-07	1.4e-07	1.0e+00	100	ASCC2
104	22	39192995	40571499	1	1	3.0e-07	6.1e-09	1.5e-03	70	MGAT3
105	22	42210985	43615241	1	1	5.6e-08	2.2e-05	7.2e-06	-12	RRP7A

Pleiotropic Associations

Trait	chisq ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	corr	corr P	genes
Bipolar Disorder (2018)	1.74	2	0	0.0	0.00	1.0e+00	ADD3 STK4
Bipolar Disorder or Schizophrenia	2.31	9	6	13.3	0.54	1.3e-01	ACTR1A C2orf82 FTSJ2 MGAT3 MPHOSPH9 MPP6 RP11-261C10.5 ST3GAL3 STK4
Depressed Affect (Nagel 2018)	3.11	13	6	13.3	-0.80	5.6e-04	CELF2 CELF4 DND1 GALNT16 GPX1 JMJD1C-AS1 LINC00461 MST1R RABGAP1L RBM6 RNF123 RP11-261C10.5 TANK
Depression (Nagel 2018)	1.87	1	1	2.2	0.00	1.0e+00	JMJD1C-AS1
Intelligence (Savage-Jansen 2018)	7.12	56	37	82.2	0.98	8.6e-41	ACTR1A AFF3 BNIP3 CALN1 CAMKMT CEP57 CKM COX6B1 CTD-3025N20.2 CYHR1 DCAF16 DNAH11 DND1 DOT1L EFTUD1 EIF3CL ELOVL7 FAM160A1 FBXO41 FOXO3 FOXO6 FOXP1 GNL3LP1 GPX1 HYI IFT57 IST1 JMJD1C-AS1 JUND LINC00461 LMOD1 LONRF2 MAN2A1 MGAT3 MPHOSPH9 MST1R NEGR1 NOVA1 NPM3 NR2F1-AS1 PPA2 PPP2R2D RABGAP1L RBL2 RBM6 RNF123 RP11-1186N24.5 RPS26 SNX29 ST3GAL3 ST6GAL2 SYPL2 TANK TEX15 TRAIP TRMT61A
Neuroticism (Nagel 2018)	2.32	11	4	8.9	-0.69	1.9e-02	B3GALTL CELF2 CELF4 CTC-498M16.2 DND1 FTSJ2 GALNT16 GATC LINC00461 STK24 THEM6
Schizophrenia (2018)	2.44	7	2	4.4	0.11	8.1e-01	ACTR1A ELOVL7 FTSJ2 MGAT3 MPHOSPH9 RP11-261C10.5 ST3GAL3
Schizophrenia vs Biploar Disorder	2.07	1	0	0.0	0.00	1.0e+00	RBM6
Worry (Nagel 2018)	1.98	7	3	6.7	0.01	9.9e-01	ACTR1A B3GALTL CADM2 CTC-498M16.2 DND1 RABGAP1L STK24
Crohns Disease (2017)	1.78	6	4	8.9	0.66	1.1e-01	EIF3CL MST1R RBM6 RNF123 SNX32 TRAIP
Irritable Bowel Disease (IBD)	2.01	7	5	11.1	0.79	1.9e-02	EIF3CL MST1R RBM6 RBMS1 RNF123 TMED5 TRAIP
Ulcerative Colitis (UC)	1.84	5	4	8.9	0.80	5.3e-02	EIF3CL MST1R RBM6 RNF123 TRAIP
Major Depression (MDD)	1.98	2	1	2.2	0.00	1.0e+00	NEGR1 TRMT61A
Reaction Time	1.76	3	1	2.2	0.00	1.0e+00	CYHR1 EXT1 FOXO3
Verbal and Numeric Reasoning (VNR)	6.18	34	22	48.9	0.97	2.9e-23	AFF3 CALN1 CKM CYHR1 DCAF16 DND1 EIF3CL FAM160A1 FBXO41 FOXO3 FOXO6 FOXP1 IFT57 JMJD1C-AS1 LINC00461 LONRF2 MGAT3 MST1R NEGR1 NPM3 NR2F1-AS1 PPA2 RBL2 RBM6 RNF123 RPS26 SNX29 ST3GAL3 ST6GAL2 SYPL2 TANK TEX15 TRAIP TRMT61A
Breast Cancer	1.36	4	2	4.4	-0.54	4.6e-01	B3GNT1 DND1 METTL10 RP11-767N6.2
Ovarian Cancer	1.29	1	1	2.2	0.00	1.0e+00	DND1
Prostate Cancer	1.83	2	1	2.2	0.00	1.0e+00	MDM4 PPA2
Age at First Birth	3.75	5	4	8.9	1.00	1.6e-05	CYHR1 MST1R RBM6 RNF123 TRAIP
Bipolar Disorder (2011)	1.82	1	0	0.0	0.00	1.0e+00	B3GNT1
Body Mass Index (BMI) (2010)	2.46	3	2	4.4	0.00	1.0e+00	EIF3CL NEGR1 TRIM73
Crohns Disease (2012)	1.95	4	4	8.9	0.95	5.0e-02	EIF3CL MST1R RNF123 TRAIP
HDL Cholesterol	1.50	3	0	0.0	0.00	1.0e+00	RBM6 TCAP TMED5
LDL Cholesterol	1.07	1	1	2.2	0.00	1.0e+00	SYPL2
Neuroticism (2016)	1.80	4	1	2.2	-0.66	3.4e-01	DND1 LINC00461 STK24 TANK
Primary Biliary Cirrhosis	1.26	2	0	0.0	0.00	1.0e+00	DND1 TCAP
Schizophrenia (2014)	2.09	7	5	11.1	0.72	6.8e-02	ACTR1A C2orf82 FTSJ2 MGAT3 MPHOSPH9 RP11-261C10.5 STK4
Ulcerative Colitis	1.72	4	2	4.4	0.99	7.3e-04	MST1R RBM6 RNF123 TRAIP
Blood Eosinophil Count	1.24	17	14	31.1	0.02	9.5e-01	ADD3 CACNA1H CCDC24 CKM DND1 GPX1 IL12RB1 INO80E MPHOSPH9 MST1R PRUNE RBM6 RP11-298I3.1 RPS26 SNX32 TMED5 TRAIP
Blood Platelet Count	1.41	25	19	42.2	-0.13	5.3e-01	ADD3 C18orf8 CKM DCAF16 DND1 EDEM3 EIF2C2 FAM160A1 GRK4 INO80E JMJD1C-AS1 LINC00461 METTL10 MPHOSPH9 MPP6 PRDX5 RP11-767N6.2 RP11-864G5.3 RRP7A SNX32 STAG3L5P-PVRIG2P-PILRB TCAP TMED5 TRMT61A WDR24
Blood Red Count	1.41	17	12	26.7	-0.39	1.1e-01	AFF3 CEP57 CKM CTC-498M16.2 DND1 EFTUD1 EIF3CL INO80E LINC00461 MAP4 MPHOSPH9 RABGAP1L RP11-767N6.2 RPS26 TCAP TMED5 TRAIP
Blood White Count	1.51	28	19	42.2	-0.65	1.3e-04	ACTR1A ASCC2 C18orf8 CACNA1H CAMKMT CKM CTC-498M16.2 DCAF16 DND1 FAM160A1 FASTKD5 GRK4 INO80E JMJD1C-AS1 METTL10 MGAT3 MST1R PPA2 PRUNE RBM6 RNF123 RP11-864G5.3 RRP7A SEMA6D STAG3L5P-PVRIG2P-PILRB TEX15 TRAIP TRMT61A
Heel T-Score	1.29	20	16	35.6	-0.14	5.5e-01	ASCC2 C11orf83 C2orf82 DCAF16 DND1 IL12RB1 INO80E METTL10 MPHOSPH9 MST1R NEGR1 PROCR RAB11FIP4 RBM6 RP11-166B2.1 RP11-767N6.2 SNX32 STAG3L5P-PVRIG2P-PILRB TRAIP TRMT61A
BMI	3.92	41	27	60.0	-0.71	1.2e-07	ACTR1A C18orf8 CADM2 CPNE3 CTC-498M16.2 DOT1L EDEM3 EIF3CL FOXO3 FOXP1 GALNT16 GPX1 GRK4 IFT57 IL12RB1 INO80E JUND LINC00461 LMOD1 LONRF2 MAP4 METTL10 MST1R NAT6 NEGR1 NR2F1-AS1 PKP4 PRDX5 PRUNE RBM6 RGS6 RNF123 RPS26 SNX32 STAG3L5P-PVRIG2P-PILRB STK24 SYPL2 TEX15 THEM6 TRAIP TRIM73
Height	1.71	45	36	80.0	0.49	6.3e-04	AFF3 C18orf8 C2orf82 C9orf5 CACNA1H CAMKMT CCDC144B CEP57 COX6B1 CPNE3 DCAF16 DCP2 DND1 EIF2C2 ELOVL7 FAM160A1 FASTKD5 FOXO3 GGACT INO80E IST1 MDM4 METTL10 MGAT3 MPHOSPH9 MPP6 PPA2 PPP2R2D PROCR PRUNE RAB11FIP4 RBL2 RP11-1186N24.5 RP11-166B2.1 RP11-767N6.2 RP11-864G5.3 SNX32 ST3GAL3 STAG3L5P-PVRIG2P-PILRB STK4 TBCE TMED5 TRIM73 TRMT61A WDR24
Waist Hip Ratio (WHR)	1.72	14	9	20.0	-0.95	1.2e-07	AFF3 C11orf83 C9orf5 CCDC144B DND1 GNL3LP1 IL12RB1 JUND MGAT3 MPHOSPH9 PRDX5 PROCR RBL2 SEMA6D
Systolic Blood Pressure	1.64	20	9	20.0	-0.28	1.9e-01	ACTR1A CCDC144B DCAF16 DND1 EDEM3 FBXO41 FOXO3 HERC4 HYI MAP4 MPP6 PPP2R2D PRDX5 RNF123 RP11-166B2.1 RP11-298I3.1 SNX32 ST6GAL2 TRAIP TRIM73
Smoking Status	3.83	24	9	20.0	-0.87	1.2e-08	ACTR1A CADM2 CELF2 CKM DND1 EFTUD1 ELOVL7 FOXP1 GGACT GNL3LP1 IFT57 LONRF2 MAP4 MST1R NAT6 PTK2 RABGAP1L RP11-767N6.2 RPS26 SEMA6D SNX32 ST3GAL3 TANK WDR24
Allergy or Eczema	1.41	6	2	4.4	0.71	1.1e-01	EIF3CL MPHOSPH9 NEGR1 PRUNE RPS26 TMED5
Cardiovascular Disease	1.85	12	6	13.3	-0.57	5.5e-02	C18orf8 DCAF16 FBXO41 GRK4 LMOD1 MAP4 NEGR1 RBL2 RP11-261C10.5 SNX32 TEX15 TRIM73
Hypothyroidism (self reported)	1.37	4	2	4.4	0.44	5.6e-01	JUND PTK2 RPS26 TANK
Respiratory disease	1.56	5	1	2.2	-0.47	4.2e-01	MST1R RABGAP1L RBM6 RPS26 TCAP
Type 2 Diabetes (T2D) (2018)	1.89	6	1	2.2	-0.75	5.4e-02	CYHR1 MST1R RBL2 RBM6 SNX32 TRAIP
Lung FEV1/FVC ratio	1.57	20	14	31.1	-0.12	6.1e-01	ACTR1A ADD3 AFF3 ASCC2 CCDC144B DND1 FOXO3 GPX1 IL12RB1 JMJD1C-AS1 JUND LMOD1 NEGR1 PPA2 RBMS1 RNF123 RP11-298I3.1 RP11-767N6.2 RPS26 STAG3L5P-PVRIG2P-PILRB
Lung FVC	1.87	20	13	28.9	0.19	4.2e-01	B3GNT1 C11orf83 C18orf8 CYHR1 DCAF16 DND1 EIF3CL FOXO3 FOXO6 FOXP1 JMJD1C-AS1 JUND MDM4 MPHOSPH9 MST1R NR2F1-AS1 PROCR RNF123 RPS26 TCAP
Neuroticism	2.34	9	5	11.1	-0.66	5.4e-02	B3GALTL CELF4 CTC-498M16.2 DND1 GALNT16 GPX1 LINC00461 RABGAP1L STK24
Chronotype (morning person)	1.42	1	0	0.0	0.00	1.0e+00	MST1R
Hair Pigment	0.33	9	6	13.3	-0.40	2.9e-01	ADD3 B3GNT1 DND1 EXT1 FOXO3 JMJD1C-AS1 MPHOSPH9 PROCR RPS26
Tanning	0.69	3	3	6.7	-0.08	9.2e-01	CADM2 IST1 PROCR
Hand grip strength (left)	1.83	10	5	11.1	0.02	9.5e-01	ACTR1A AFF3 CADM2 CALN1 DCAF16 DND1 FOXP1 NPM3 PROCR STAG3L5P-PVRIG2P-PILRB
Number of treatments/medications taken	2.97	11	4	8.9	-0.97	1.3e-07	B3GALTL DCAF16 FBXO41 MST1R PPP2R2D RABGAP1L RBM6 RNF123 ST6GAL2 TANK TRAIP
Sensitivity / hurt feelings	1.96	2	1	2.2	0.00	1.0e+00	CELF4 DND1
Frequency of depressed mood in last 2 weeks	1.70	1	1	2.2	0.00	1.0e+00	JMJD1C-AS1
Hearing difficulty/problems: Yes	1.34	2	1	2.2	0.00	1.0e+00	PTK2 RP11-767N6.2
Relative age of first facial hair	2.12	4	1	2.2	-0.34	6.6e-01	DND1 FOXO3 PRUNE RABGAP1L
Systolic blood pressure, automated reading	1.91	12	4	8.9	-0.72	8.1e-03	DCAF16 DND1 EDEM3 FBXO41 MPP6 PKP4 PPA2 PROCR RNF123 RP11-298I3.1 SNX32 TRIM73
Medication: Co-codamol	2.08	3	0	0.0	-1.00	1.2e-03	MST1R RBM6 RNF123
Pack years adult smoking proportion	2.32	6	1	2.2	-0.16	7.7e-01	BNIP3 CELF4 GPX1 GRK4 JMJD1C-AS1 SEMA6D
Impedance of leg (right)	2.11	25	18	40.0	0.26	1.9e-01	ACTR1A B3GNT1 EIF3CL FAM160A1 INO80E JUND LINC00461 LMOD1 MST1R NAT6 NEGR1 PPA2 PTK2 RBL2 RBM6 RBMS1 RGS6 RNF123 RPS26 SEMA6D SLC35A1 SNX32 STAG3L5P-PVRIG2P-PILRB SYPL2 TRIM73
Leg fat-free mass (left)	2.64	29	23	51.1	-0.31	9.9e-02	ACTR1A C18orf8 C9orf5 CADM2 CTC-498M16.2 DCAF16 EIF3CL FAM160A1 FOXO3 INO80E LINC00461 LMOD1 MGAT3 MPHOSPH9 MST1R NAT6 NEGR1 PPA2 PRDX5 PROCR RBL2 RBM6 RNF123 RPS26 SNX32 SYPL2 TRAIP TRIM38 TRIM73
Trunk fat percentage	3.10	27	18	40.0	-0.67	1.1e-04	C11orf83 C18orf8 CADM2 DND1 EDEM3 EIF3CL FOXO3 FOXP1 GALNT16 IL12RB1 INO80E JUND LINC00461 LMOD1 LONRF2 METTL10 MPP6 MST1R NEGR1 RBM6 RNF123 SNX32 STK24 TEX15 THEM6 TRAIP TRIM73
Hand grip strength (right)	1.76	7	4	8.9	0.27	5.6e-01	ACTR1A DCAF16 DND1 EIF3CL NPM3 PROCR STAG3L5P-PVRIG2P-PILRB
Current tobacco smoking	2.80	4	2	4.4	-0.98	2.4e-02	ACTR1A CADM2 SEMA6D ST3GAL3
Maternal smoking around birth	2.78	5	1	2.2	-0.93	2.0e-02	ACTR1A ARTN CKM MST1R NAT6
Fed-up feelings	3.36	13	5	11.1	-0.87	5.6e-05	B3GNT1 CELF4 DND1 GALNT16 GPX1 LINC00461 LONRF2 MST1R PRDX5 RBM6 RNF123 THEM6 TRAIP
Frequency of unenthusiasm / disinterest in last 2 weeks	2.53	2	1	2.2	0.00	1.0e+00	GALNT16 JMJD1C-AS1
Relative age voice broke	1.87	2	1	2.2	0.00	1.0e+00	DND1 FOXO3
Taking other prescription medications	2.48	5	4	8.9	-1.00	2.5e-05	B3GALTL MST1R RBM6 RNF123 TRAIP
Age when periods started (menarche)	2.74	13	9	20.0	-0.44	9.1e-02	C9orf5 COX6B1 FOXO3 HYI INO80E MST1R NAT6 NEGR1 RNF123 RRP7A SNX32 ST3GAL3 TRIM73
Heel bone mineral density (BMD) T-score, automated (left)	1.10	3	1	2.2	0.00	1.0e+00	MST1R PROCR TRAIP
Qualifications: CSEs or equivalent	3.09	3	0	0.0	-0.68	3.2e-01	FOXO6 MST1R RNF123
High blood pressure	1.80	9	1	2.2	-0.36	3.4e-01	DCAF16 FBXO41 NEGR1 PTK2 RBL2 RP11-261C10.5 SNX32 TEX15 TRIM73
Hayfever, allergic rhinitis or eczema	1.37	2	1	2.2	0.00	1.0e+00	MPHOSPH9 RPS26
Medication: Levothyroxine sodium	1.21	1	1	2.2	0.00	1.0e+00	RPS26
Sitting height	1.91	15	11	24.4	0.83	1.5e-04	C2orf82 DCAF16 DND1 EIF2C2 FOXO3 MGAT3 MPHOSPH9 PPA2 PPP2R2D PROCR RBL2 RP11-767N6.2 SLC35A1 TRIM38 WDR24
Body mass index (BMI)	4.08	34	21	46.7	-0.79	1.2e-08	ACTR1A C18orf8 CADM2 CPNE3 CTC-498M16.2 DOT1L EDEM3 EIF3CL FOXO3 FOXP1 GPX1 GRK4 IFT57 IL12RB1 INO80E LINC00461 LMOD1 LONRF2 MAP4 MPP6 MST1R NAT6 NEGR1 PKP4 RBM6 RBMS1 RGS6 RNF123 RPS26 SNX32 STK24 TEX15 TRAIP TRIM73
Impedance of leg (left)	2.15	25	19	42.2	0.26	2.0e-01	ACTR1A B3GNT1 EIF3CL FAM160A1 INO80E JUND LINC00461 LMOD1 MST1R NAT6 NEGR1 PPA2 PTK2 RBL2 RBM6 RBMS1 RGS6 RNF123 RPS26 SEMA6D SLC35A1 SNX32 STAG3L5P-PVRIG2P-PILRB SYPL2 TRIM73
Leg predicted mass (left)	2.65	29	23	51.1	-0.30	1.0e-01	ACTR1A C18orf8 C9orf5 CADM2 CTC-498M16.2 DCAF16 EIF3CL FAM160A1 FOXO3 INO80E LINC00461 LMOD1 MGAT3 MPHOSPH9 MST1R NAT6 NEGR1 PPA2 PRDX5 PROCR RBL2 RBM6 RNF123 RPS26 SNX32 SYPL2 TRAIP TRIM38 TRIM73
Trunk fat mass	3.23	26	20	44.4	-0.72	1.9e-05	C18orf8 CADM2 CTC-498M16.2 EIF3CL FOXO3 FOXP1 GALNT16 IL12RB1 INO80E JUND LINC00461 LMOD1 LONRF2 METTL10 MST1R NEGR1 PRDX5 RBM6 RGS6 RNF123 SNX32 STK24 TEX15 THEM6 TRAIP TRIM73
Waist circumference	3.50	26	19	42.2	-0.74	8.6e-06	C18orf8 C9orf5 CADM2 CTC-498M16.2 EIF3CL FOXO3 IL12RB1 INO80E JUND LINC00461 LMOD1 LONRF2 METTL10 MST1R NAT6 NEGR1 RBM6 RGS6 RNF123 RPS26 SNX32 STK24 TEX15 THEM6 TRAIP TRIM73
Number of incorrect matches in round	1.94	3	2	4.4	0.00	1.0e+00	EXT1 INO80E NPM3
Past tobacco smoking	2.80	9	2	4.4	0.79	6.6e-03	ACTR1A C18orf8 CADM2 CYHR1 GGACT MAP4 NAT6 TANK WDR24
Alcohol usually taken with meals	4.33	11	4	8.9	0.97	2.9e-08	ACTR1A ARTN CADM2 CELF4 ELOVL7 FOXP1 GNL3LP1 HYI LONRF2 NEGR1 RABGAP1L
Nervous feelings	1.80	7	4	8.9	0.17	6.8e-01	ACTR1A B3GALTL CADM2 CTC-498M16.2 DND1 INO80E STK24
Frequency of tenseness / restlessness in last 2 weeks	1.98	3	2	4.4	0.00	1.0e+00	B3GALTL DND1 MST1R
Hair/balding pattern: Pattern 2	1.07	1	0	0.0	0.00	1.0e+00	GGACT
Had other major operations	1.75	1	0	0.0	0.00	1.0e+00	PPA2
Forced vital capacity (FVC)	1.93	11	5	11.1	0.63	3.7e-02	C11orf83 DCAF16 DND1 FOXP1 IST1 MDM4 MST1R PPA2 PPP2R2D RBL2 RNF123
Heel bone mineral density (BMD) T-score, automated (right)	1.12	4	0	0.0	-0.83	1.7e-01	DCAF16 MST1R PROCR TRAIP
Ever unenthusiastic/disinterested for a whole week	1.51	1	0	0.0	0.00	1.0e+00	DND1
Qualifications: None of the above	9.28	57	33	73.3	-0.98	3.2e-45	ACTR1A AFF3 ARTN B3GALTL B3GNT1 BNIP3 C9orf5 CCDC24 CELF2 CELF4 CEP57 CKM CTC-498M16.2 DNAH11 EIF3CL ELOVL7 FAM160A1 FOXO3 FOXP1 FPGT FTSJ2 GNL3LP1 GPX1 GRK4 HYI IFT57 IST1 JMJD1C-AS1 LONRF2 MAN2A1 MAP4 MPHOSPH9 MPP6 MST1R NAT6 NEGR1 NPM3 NR2F1-AS1 PPA2 PPP2R2D RBL2 RBM6 RNF123 RP11-261C10.5 RPS26 SLC35A1 SNX29 ST3GAL3 ST6GAL2 SYPL2 TANK TEX15 THEM6 TMED5 TRAIP TRIM38 WDR24
Mouth/teeth dental problems	2.13	2	0	0.0	0.00	1.0e+00	DND1 RP11-261C10.5
Allergy	1.39	3	2	4.4	0.00	1.0e+00	AFF3 MPHOSPH9 RPS26
Diabetes (self-reported)	1.99	3	0	0.0	0.00	1.0e+00	RBL2 RBM6 TRAIP
Hayfever/allergic rhinitis (self-reported)	1.37	1	0	0.0	0.00	1.0e+00	RPS26
Fluid intelligence score	6.49	39	20	44.4	0.98	4.9e-29	AFF3 ARTN BNIP3 C20orf197 CALN1 CCDC24 CKM CTD-3025N20.2 CYHR1 DCAF16 DND1 EIF3CL FAM160A1 FBXO41 FOXO3 FOXO6 FOXP1 HYI IFT57 JMJD1C-AS1 LONRF2 MGAT3 MPHOSPH9 MST1R NEGR1 NPM3 NR2F1-AS1 PPA2 RBL2 RBM6 RNF123 RPS26 ST3GAL3 ST6GAL2 STAG3L5P-PVRIG2P-PILRB SYPL2 TANK TRAIP TRMT61A
Illnesses of siblings	1.72	1	1	2.2	0.00	1.0e+00	RBL2
Neuroticism score	2.40	8	4	8.9	-0.78	2.3e-02	B3GALTL CELF4 DND1 GALNT16 GPX1 LINC00461 RABGAP1L STK24
Weight	3.25	30	22	48.9	-0.59	5.4e-04	ACTR1A C18orf8 C9orf5 CADM2 CTC-498M16.2 DCAF16 EIF3CL FOXO3 IFT57 INO80E LINC00461 LMOD1 LONRF2 METTL10 MPHOSPH9 MST1R NAT6 NEGR1 PRDX5 PROCR RBL2 RBM6 RNF123 RPS26 SNX32 TEX15 THEM6 TRAIP TRIM38 TRIM73
Impedance of arm (right)	2.67	28	21	46.7	0.67	4.6e-05	ACTR1A C11orf83 CADM2 CTC-498M16.2 DND1 ELOVL7 FOXO3 GATC GPX1 INO80E JMJD1C-AS1 JUND LMOD1 MST1R NAT6 NEGR1 PRUNE RBM6 RBMS1 RGS6 RNF123 RP11-864G5.3 RPS26 SNX32 STAG3L5P-PVRIG2P-PILRB SYPL2 TRAIP TRIM73
Arm fat percentage (right)	3.42	32	20	44.4	-0.72	2.5e-06	C11orf83 C18orf8 CADM2 CTC-498M16.2 DCAF16 EDEM3 EIF3CL FOXO3 FOXP1 IFT57 IL12RB1 INO80E JUND LINC00461 LMOD1 LONRF2 MAP4 METTL10 MPP6 MST1R NEGR1 PKP4 RBM6 RGS6 RNF123 SEMA6D SNX32 STK24 TEX15 THEM6 TRAIP TRIM73
Trunk fat-free mass	2.49	27	20	44.4	-0.18	3.7e-01	ACTR1A C18orf8 CADM2 CTC-498M16.2 DCAF16 EIF3CL ELOVL7 FAM160A1 FOXO3 GNL3LP1 INO80E LMOD1 MGAT3 MPHOSPH9 MST1R NAT6 PPA2 PROCR RBL2 RBM6 RNF123 RPS26 SYPL2 TRAIP TRIM38 TRMT61A WDR24
Hip circumference	2.81	25	18	40.0	-0.53	5.5e-03	ACTR1A C18orf8 CADM2 CTC-498M16.2 DCAF16 EIF3CL FOXO3 INO80E LINC00461 LMOD1 LONRF2 METTL10 MPHOSPH9 MST1R NAT6 NEGR1 PRDX5 RBL2 RBM6 RNF123 SNX32 THEM6 TRAIP TRIM38 TRIM73
Alcohol intake versus 10 years previously	3.27	7	4	8.9	-0.71	3.1e-02	ARTN CCDC24 MST1R NEGR1 RBM6 RNF123 TRAIP
Father's age at death	2.10	1	0	0.0	0.00	1.0e+00	RNF123
Worrier / anxious feelings	1.96	4	1	2.2	0.09	9.1e-01	ACTR1A B3GALTL CADM2 DND1
Frequency of tiredness / lethargy in last 2 weeks	2.01	2	0	0.0	0.00	1.0e+00	GALNT16 JMJD1C-AS1
Falls in the last year	1.45	1	0	0.0	0.00	1.0e+00	TCAP
Hair/balding pattern: Pattern 3	1.64	2	1	2.2	0.00	1.0e+00	DND1 GGACT
Number of live births	2.44	1	0	0.0	0.00	1.0e+00	CADM2
Forced expiratory volume in 1-second (FEV1)	2.09	12	8	17.8	0.54	6.7e-02	C11orf83 DCAF16 DND1 FOXP1 GPX1 MDM4 MST1R PPA2 PPP2R2D RNF123 RPS26 TRIM38
Pulse rate	1.19	1	0	0.0	0.00	1.0e+00	RBL2
Qualifications: A levels/AS levels or equivalent	8.53	53	20	44.4	0.99	3.6e-49	ACTR1A ARTN CADM2 CAMKMT CCDC24 CELF2 CEP57 CKM COX6B1 CPNE3 CTD-3025N20.2 DCAF16 DDX31 DND1 ELOVL7 FAM160A1 FASTKD5 FBXO41 FOXO6 FTSJ2 GNL3LP1 HYI IFT57 JMJD1C-AS1 JUND LONRF2 MAP4 MGAT3 MPHOSPH9 MPP6 MST1R NEGR1 NOVA1 NPM3 PPA2 RAB11FIP4 RBL2 RBM6 RNF123 RP11-261C10.5 RPS26 RRP7A SNX29 ST3GAL3 ST6GAL2 TANK THEM6 TMED5 TRAIP TRIM38 TRIM73 TRMT61A WDR24
Mouth/teeth dental problems: Dentures	2.86	6	2	4.4	-0.99	1.2e-05	INO80E MST1R NOVA1 RBM6 RNF123 TMED5
Asthma	1.60	4	3	6.7	0.18	8.2e-01	AFF3 RPS26 TCAP TRIM38
Forced expiratory volume in 1-second (FEV1), Best measure	2.15	11	7	15.6	0.47	1.4e-01	C11orf83 DCAF16 DND1 FOXP1 GPX1 MDM4 MST1R PPA2 RNF123 RPS26 TRIM38
Impedance of arm (left)	2.60	25	22	48.9	0.75	6.0e-06	ACTR1A C11orf83 CADM2 CTC-498M16.2 DND1 FOXO3 GPX1 INO80E JMJD1C-AS1 JUND LMOD1 MST1R NAT6 NEGR1 PRUNE RBM6 RBMS1 RNF123 RP11-864G5.3 RPS26 SNX32 STAG3L5P-PVRIG2P-PILRB SYPL2 TRAIP TRIM73
Arm fat mass (right)	3.72	30	20	44.4	-0.75	1.1e-06	C18orf8 CADM2 CTC-498M16.2 EDEM3 EIF3CL FOXO3 FOXP1 IFT57 IL12RB1 INO80E JUND LINC00461 LMOD1 LONRF2 MAP4 METTL10 MST1R NAT6 NEGR1 PRDX5 RBM6 RGS6 RNF123 RPS26 SNX32 STK24 TEX15 THEM6 TRAIP TRIM73
Trunk predicted mass	2.49	28	20	44.4	-0.15	4.5e-01	ACTR1A C18orf8 CADM2 CTC-498M16.2 DCAF16 EIF3CL ELOVL7 FAM160A1 FOXO3 GNL3LP1 INO80E LMOD1 MGAT3 MPHOSPH9 MST1R NAT6 NEGR1 PPA2 PROCR RBL2 RBM6 RNF123 RPS26 SYPL2 TRAIP TRIM38 TRMT61A WDR24
Standing height	1.83	27	16	35.6	0.67	1.4e-04	AFF3 C18orf8 C2orf82 CACNA1H CCDC144B DCAF16 DND1 EIF2C2 FAM160A1 FOXO3 GGACT GRK4 MPHOSPH9 MPP6 PPA2 PPP2R2D PROCR RAB11FIP4 RBL2 RP11-767N6.2 RRP7A SNX32 STAG3L5P-PVRIG2P-PILRB TBCE TRIM38 TRIM73 WDR24
Exposure to tobacco smoke at home	1.99	2	1	2.2	0.00	1.0e+00	MST1R RNF123
Breastfed as a baby	1.87	1	0	0.0	0.00	1.0e+00	MPHOSPH9
Tense / 'highly strung'	1.42	1	0	0.0	0.00	1.0e+00	RABGAP1L
Seen doctor (GP) for nerves, anxiety, tension or depression	2.19	3	1	2.2	0.00	1.0e+00	B3GALTL CELF4 NEGR1
Hair/balding pattern: Pattern 4	1.37	2	2	4.4	0.00	1.0e+00	DND1 METTL10
Birth weight of first child	1.98	6	3	6.7	0.60	2.1e-01	DCAF16 PPA2 PTK2 RP11-864G5.3 RPS26 TRIM73
Peak expiratory flow (PEF)	1.53	5	2	4.4	0.70	1.9e-01	DCAF16 DND1 FOXO3 MDM4 NR2F1-AS1
Ever highly irritable/argumentative for 2 days	2.26	2	1	2.2	0.00	1.0e+00	MST1R RBM6
Qualifications: O levels/GCSEs or equivalent	4.41	8	1	2.2	0.95	3.4e-04	CKM FTSJ2 IFT57 MPHOSPH9 MPP6 MST1R RNF123 THEM6
Blood clot in the leg (DVT)	1.15	1	0	0.0	0.00	1.0e+00	PROCR
Medication: Paracetamol	2.39	5	3	6.7	-0.99	1.0e-03	DND1 PTK2 RABGAP1L RP11-261C10.5 TMED5
Headache pain in last month	1.66	3	2	4.4	0.00	1.0e+00	DND1 RP11-261C10.5 RPS26
Hypothyroidism/myxoedema (self-reported)	1.23	2	1	2.2	0.00	1.0e+00	RPS26 TANK
Medication: Ventolin 100micrograms inhaler	1.64	2	0	0.0	0.00	1.0e+00	AFF3 RPS26
Birth weight	1.81	5	2	4.4	0.78	1.2e-01	DCAF16 PPA2 PTK2 RP11-864G5.3 SLC35A1
Chronic bronchitis/emphysema (mother)	1.70	1	0	0.0	0.00	1.0e+00	MST1R
Forced vital capacity (FVC), Best measure	2.03	11	5	11.1	0.58	6.3e-02	C11orf83 DCAF16 DND1 FOXP1 IST1 MDM4 MST1R PPA2 RBL2 RNF123 TRIM38
Body fat percentage	3.57	32	20	44.4	-0.75	4.1e-07	C11orf83 C18orf8 CADM2 CTC-498M16.2 DCAF16 EDEM3 EIF3CL FOXO3 FOXP1 GALNT16 GRK4 IL12RB1 INO80E JUND LINC00461 LMOD1 LONRF2 METTL10 MPP6 MST1R NEGR1 PKP4 RBM6 RGS6 RNF123 RP11-121L10.3 SNX32 STK24 TEX15 THEM6 TRAIP TRIM73
Leg fat percentage (right)	4.21	36	23	51.1	-0.81	9.0e-10	AFF3 BNIP3 C18orf8 CADM2 CPNE3 CTC-498M16.2 DCAF16 EDEM3 EIF3CL FOXO3 FOXP1 GALNT16 GPX1 GRK4 IFT57 IL12RB1 INO80E JUND LINC00461 LMOD1 LONRF2 METTL10 MPP6 MST1R NEGR1 PKP4 RBM6 RGS6 RNF123 RP11-767N6.2 SNX32 STK24 TEX15 THEM6 TRAIP TRIM73
Arm fat-free mass (right)	2.83	29	22	48.9	-0.33	7.0e-02	ACTR1A C18orf8 CADM2 CTC-498M16.2 DCAF16 EIF3CL ELOVL7 FAM160A1 FOXO3 INO80E LINC00461 LMOD1 MGAT3 MPHOSPH9 MST1R NAT6 NEGR1 PPA2 PROCR RBL2 RBM6 RNF123 RP11-864G5.3 RPS26 SNX32 SYPL2 TRAIP TRIM38 TRMT61A
Exposure to tobacco smoke outside home	2.50	2	0	0.0	0.00	1.0e+00	ELOVL7 MST1R
Comparative body size at age 10	2.22	10	5	11.1	-0.29	3.9e-01	C18orf8 CADM2 CTC-498M16.2 EIF3CL FPGT MAP4 NAT6 NEGR1 PRUNE TNNI3K
Worry too long after embarrassment	1.66	1	0	0.0	0.00	1.0e+00	DND1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.48	1	0	0.0	0.00	1.0e+00	TRMT61A
Wheeze or whistling in the chest in last year	2.59	8	3	6.7	-0.98	3.2e-06	AFF3 DOT1L MAP4 MST1R RABGAP1L RBM6 RNF123 TRAIP
Number of children fathered	1.71	1	0	0.0	0.00	1.0e+00	CADM2
Reason for reducing amount of alcohol drunk: Health precaution	1.69	1	0	0.0	0.00	1.0e+00	CTC-498M16.2
Age at first live birth	5.11	13	5	11.1	0.99	9.2e-13	ARTN C20orf197 CCDC24 CELF4 CEP57 CPNE3 DCAF16 GPX1 MST1R RBM6 RNF123 RPS26 TRAIP
Health satisfaction	1.93	1	0	0.0	0.00	1.0e+00	LMOD1
Shortness of breath walking on level ground	1.82	1	0	0.0	0.00	1.0e+00	C18orf8
Medication for pain relief, constipation, heartburn	2.37	7	1	2.2	0.99	6.7e-06	CEP57 DND1 MPHOSPH9 PTK2 RABGAP1L RP11-261C10.5 ST6GAL2
Neck or shoulder pain in last month	2.26	1	0	0.0	0.00	1.0e+00	RPS26
Medication: Blood pressure	1.92	3	0	0.0	0.00	1.0e+00	DCAF16 FBXO41 MAP4
Mean time to correctly identify matches	1.73	3	1	2.2	0.00	1.0e+00	CYHR1 FOXO3 IFT57
Whole body fat mass	3.67	28	21	46.7	-0.76	1.6e-06	C18orf8 CADM2 CTC-498M16.2 EDEM3 EIF3CL FOXO3 FOXP1 GALNT16 GPX1 IFT57 IL12RB1 INO80E JUND LINC00461 LMOD1 LONRF2 METTL10 MST1R NEGR1 RBM6 RGS6 RNF123 SNX32 STK24 TEX15 THEM6 TRAIP TRIM73
Leg fat mass (right)	4.14	33	22	48.9	-0.79	2.0e-08	ACTR1A C18orf8 CADM2 CPNE3 CTC-498M16.2 EDEM3 EIF3CL FOXO3 FOXP1 GALNT16 GPX1 IFT57 IL12RB1 INO80E JUND LINC00461 LMOD1 LONRF2 METTL10 MPP6 MST1R NAT6 NEGR1 RBM6 RGS6 RNF123 RPS26 SNX32 STK24 TEX15 THEM6 TRAIP TRIM73
Arm predicted mass (right)	2.86	29	21	46.7	-0.34	6.3e-02	ACTR1A C18orf8 CADM2 CTC-498M16.2 DCAF16 EIF3CL ELOVL7 FAM160A1 FOXO3 INO80E LINC00461 LMOD1 MGAT3 MPHOSPH9 MST1R NAT6 NEGR1 PPA2 PROCR RBL2 RBM6 RNF123 RP11-864G5.3 RPS26 SNX32 SYPL2 TRAIP TRIM38 TRMT61A
Pulse rate, automated reading	1.65	11	5	11.1	-0.29	3.5e-01	CTC-498M16.2 HYI LINC00461 MST1R NEGR1 RABGAP1L RBL2 RBM6 RP11-864G5.3 TRAIP TRIM73
Alcohol intake frequency.	3.67	17	10	22.2	-0.93	2.4e-08	BNIP3 C18orf8 CCDC144B CTC-498M16.2 DND1 EIF3CL FOXP1 GALNT16 INO80E IST1 MPHOSPH9 MST1R RBM6 RBMS1 STAG3L5P-PVRIG2P-PILRB TEX15 TRAIP
Comparative height size at age 10	1.83	21	14	31.1	0.26	2.6e-01	ARTN C18orf8 CCDC144B DCAF16 DND1 EIF3CL FAM160A1 FOXO3 HYI INO80E JUND METTL10 MPHOSPH9 PROCR RAB11FIP4 RBL2 RP11-767N6.2 ST3GAL3 TMED5 TRIM38 WDR24
Number of full sisters	2.05	1	0	0.0	0.00	1.0e+00	CADM2
Suffer from 'nerves'	1.61	1	1	2.2	0.00	1.0e+00	EIF3CL
Overall health rating	4.42	22	11	24.4	-0.97	1.7e-14	B3GALTL CKM DOT1L EIF2C2 FASTKD5 FOXP1 GALNT16 GPX1 GRK4 LMOD1 MST1R RABGAP1L RBL2 RBM6 RGS6 RNF123 RP11-261C10.5 SNX32 TANK TEX15 THEM6 TRAIP
Age at last live birth	3.78	6	4	8.9	0.99	6.8e-06	LONRF2 MST1R NAT6 RBM6 RNF123 TRAIP
Leg pain on walking	2.50	4	1	2.2	-1.00	1.6e-04	MST1R RBM6 RNF123 TRAIP
Qualifications: NVQ or HND or HNC or equivalent	2.64	1	0	0.0	0.00	1.0e+00	RBM6
Knee pain experienced in last month	2.35	5	0	0.0	-0.97	7.4e-03	MST1R PROCR PTK2 RBM6 RP11-261C10.5
Hypertension (Self-reported)	1.77	10	2	4.4	-0.55	9.8e-02	DCAF16 FBXO41 LMOD1 MAP4 NEGR1 RBL2 RP11-261C10.5 SNX32 TEX15 TRIM73
Smoking status: Previous	2.26	3	1	2.2	-0.65	3.5e-01	C18orf8 CADM2 CYHR1
Forced expiratory volume in 1-second (FEV1), predicted	1.41	1	1	2.2	0.00	1.0e+00	DCAF16
Whole body fat-free mass	2.60	31	22	48.9	-0.22	2.3e-01	ACTR1A C18orf8 C9orf5 CADM2 CTC-498M16.2 DCAF16 EIF3CL ELOVL7 FAM160A1 FOXO3 GNL3LP1 INO80E LINC00461 LMOD1 MGAT3 MPHOSPH9 MST1R NAT6 NEGR1 PPA2 PROCR RBL2 RBM6 RNF123 RPS26 SNX32 SYPL2 TRAIP TRIM38 TRMT61A WDR24
Leg fat-free mass (right)	2.56	31	23	51.1	-0.23	2.1e-01	ACTR1A C18orf8 C9orf5 CACNA1H CADM2 CTC-498M16.2 DCAF16 EIF3CL FAM160A1 FOXO3 INO80E LINC00461 LMOD1 MGAT3 MPHOSPH9 MST1R NAT6 NEGR1 PPA2 PROCR RBL2 RBM6 RNF123 RPS26 SLC35A1 SNX32 SYPL2 TRAIP TRIM38 TRIM73 WDR24
Arm fat percentage (left)	3.39	30	21	46.7	-0.76	8.1e-07	C18orf8 CADM2 CTC-498M16.2 DCAF16 EDEM3 EIF3CL FOXP1 GRK4 IL12RB1 INO80E JUND LINC00461 LMOD1 LONRF2 MAP4 METTL10 MPP6 MST1R NEGR1 PKP4 RBM6 RGS6 RNF123 SEMA6D SNX32 STK24 TEX15 THEM6 TRAIP TRIM73
Average weekly red wine intake	3.76	7	2	4.4	0.90	5.2e-03	B3GNT1 C18orf8 CEP57 CTC-498M16.2 FOXP1 MPHOSPH9 TMED5
Handedness (chirality/laterality): Left-handed	1.39	1	0	0.0	0.00	1.0e+00	DND1
Mood swings	2.83	9	3	6.7	-0.90	4.2e-04	CELF2 CELF4 DND1 GPX1 MST1R PTK2 RBM6 RNF123 STK24
Loneliness, isolation	2.10	1	0	0.0	0.00	1.0e+00	JMJD1C-AS1
Long-standing illness, disability or infirmity	2.13	2	0	0.0	0.00	1.0e+00	NEGR1 NR2F1-AS1
Ever had bowel cancer screening	1.52	1	0	0.0	0.00	1.0e+00	TRAIP
Diabetes diagnosed by doctor	1.83	2	0	0.0	0.00	1.0e+00	RBL2 RBM6
Friendships satisfaction	1.81	2	0	0.0	0.00	1.0e+00	C18orf8 CEP57
Qualifications: nursing, teaching	6.04	13	5	11.1	0.97	2.1e-09	ARTN CADM2 ELOVL7 GALNT16 JMJD1C-AS1 METTL10 MPHOSPH9 MST1R NEGR1 PPA2 RBM6 STK24 TRAIP
Mouth/teeth dental problems: Mouth ulcers	1.41	3	2	4.4	0.00	1.0e+00	CEP57 DND1 IL12RB1
Medication for cholesterol	1.52	1	0	0.0	0.00	1.0e+00	RBL2
Back pain experienced in last month	2.24	1	0	0.0	0.00	1.0e+00	PTK2
Mineral and other dietary supplements	1.62	2	0	0.0	0.00	1.0e+00	CTC-498M16.2 GRK4
Asthma (self-reported)	1.60	4	2	4.4	0.17	8.3e-01	AFF3 RPS26 TCAP TRIM38
Smoking status: Current	2.78	4	4	8.9	-0.99	1.4e-02	ACTR1A CADM2 SEMA6D ST3GAL3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.77	5	2	4.4	0.58	3.0e-01	C11orf83 DND1 INO80E PPA2 RNF123
Whole body water mass	2.63	31	22	48.9	-0.22	2.3e-01	ACTR1A C18orf8 C9orf5 CADM2 CTC-498M16.2 DCAF16 EIF3CL ELOVL7 FAM160A1 FOXO3 GNL3LP1 INO80E LINC00461 LMOD1 MGAT3 MPHOSPH9 MST1R NAT6 NEGR1 PPA2 PROCR RBL2 RBM6 RNF123 RPS26 SNX32 SYPL2 TRAIP TRIM38 TRMT61A WDR24
Leg predicted mass (right)	2.55	31	22	48.9	-0.23	2.1e-01	ACTR1A C18orf8 C9orf5 CACNA1H CADM2 CTC-498M16.2 DCAF16 EIF3CL FAM160A1 FOXO3 INO80E LINC00461 LMOD1 MGAT3 MPHOSPH9 MST1R NAT6 NEGR1 PPA2 PROCR RBL2 RBM6 RNF123 RPS26 SLC35A1 SNX32 SYPL2 TRAIP TRIM38 TRIM73 WDR24
Arm fat mass (left)	3.68	30	20	44.4	-0.75	1.2e-06	C18orf8 CADM2 CTC-498M16.2 EDEM3 EIF3CL FOXO3 FOXP1 IFT57 IL12RB1 INO80E JUND LINC00461 LMOD1 LONRF2 MAP4 METTL10 MST1R NAT6 NEGR1 PRDX5 RBM6 RGS6 RNF123 RPS26 SNX32 STK24 TEX15 THEM6 TRAIP TRIM73
Number of self-reported non-cancer illnesses	2.02	2	1	2.2	0.00	1.0e+00	FBXO41 NEGR1
Average weekly champagne plus white wine intake	2.80	2	0	0.0	0.00	1.0e+00	DND1 WDR24
Miserableness	2.90	11	6	13.3	-0.96	1.3e-06	B3GALTL CELF2 CELF4 DND1 FTSJ2 GPX1 MST1R RABGAP1L RBM6 RNF123 RP11-261C10.5
Financial situation satisfaction	2.12	1	0	0.0	0.00	1.0e+00	RNF123
Commuting to job workplace: Public transport	2.63	1	0	0.0	0.00	1.0e+00	LONRF2
Supplements: Fish oil (including cod liver oil)	1.66	2	0	0.0	0.00	1.0e+00	B3GNT1 GRK4
High cholesterol (Self-reported)	1.22	1	0	0.0	0.00	1.0e+00	DCAF16
Medication: Bendroflumethiazide	1.42	1	1	2.2	0.00	1.0e+00	TEX15
Medication: Paracetamol	2.43	4	1	2.2	-0.99	1.0e-02	DND1 PTK2 RABGAP1L RP11-261C10.5
Ever smoked	2.53	7	2	4.4	-0.74	3.4e-02	ACTR1A C18orf8 CADM2 GGACT GNL3LP1 MAP4 WDR24
Basal metabolic rate	2.76	28	23	51.1	-0.33	7.7e-02	ACTR1A C18orf8 C9orf5 CADM2 CTC-498M16.2 DCAF16 EIF3CL FAM160A1 FOXO3 INO80E LINC00461 LMOD1 MGAT3 MPHOSPH9 MST1R NAT6 NEGR1 PPA2 PROCR RBL2 RBM6 RNF123 RPS26 SNX32 SYPL2 TRAIP TRIM38 TRIM73
Leg fat percentage (left)	4.24	35	26	57.8	-0.81	1.6e-09	BNIP3 C18orf8 CADM2 CPNE3 CTC-498M16.2 DCAF16 EDEM3 EIF3CL FOXO3 FOXP1 GALNT16 GPX1 GRK4 IFT57 IL12RB1 INO80E JUND LINC00461 LMOD1 LONRF2 METTL10 MPP6 MST1R NEGR1 PKP4 RBM6 RGS6 RNF123 RP11-767N6.2 SNX32 STK24 TEX15 THEM6 TRAIP TRIM73
Arm fat-free mass (left)	2.88	28	21	46.7	-0.37	4.6e-02	ACTR1A C18orf8 CADM2 CTC-498M16.2 DCAF16 EIF3CL ELOVL7 FAM160A1 FOXO3 INO80E LINC00461 LMOD1 MGAT3 MPHOSPH9 MST1R NAT6 NEGR1 PPA2 PROCR RBL2 RBM6 RNF123 RP11-864G5.3 RPS26 SNX32 TRAIP TRIM38 TRMT61A
Number of operations (self-reported)	1.95	1	0	0.0	0.00	1.0e+00	MST1R
Average weekly beer plus cider intake	3.09	5	4	8.9	-0.98	4.4e-04	CELF4 MST1R RBM6 RNF123 TRAIP
Irritability	1.68	4	2	4.4	-0.18	8.2e-01	CELF4 DND1 LINC00461 TRMT61A
Risk taking	1.83	3	1	2.2	-0.66	3.4e-01	CADM2 FAM160A1 RP11-261C10.5
Ever had prostate specific antigen (PSA) test	1.17	1	0	0.0	0.00	1.0e+00	CTC-498M16.2
Diastolic blood pressure, automated reading	2.48	17	10	22.2	-0.76	2.5e-04	DCAF16 EDEM3 FBXO41 LINC00461 LMOD1 MAP4 MPHOSPH9 MPP6 MST1R PKP4 RBM6 RNF123 RP11-261C10.5 RP11-298I3.1 SNX32 TRAIP TRIM73
Unable to work because of sickness or disability	2.29	1	0	0.0	0.00	1.0e+00	DOT1L
Myopia	1.99	1	0	0.0	0.00	1.0e+00	GGACT
Vascular/heart problems diagnosed by doctor	1.89	8	1	2.2	0.60	1.1e-01	DCAF16 FBXO41 LMOD1 NEGR1 RBL2 RP11-261C10.5 SNX32 TEX15
Cholesterol lowering medication	1.42	1	0	0.0	0.00	1.0e+00	DCAF16
Pain experienced in last month	2.97	6	1	2.2	0.97	3.6e-04	DND1 MST1R PTK2 RBM6 RNF123 RPS26
Deep venous thrombosis (DVT) (self-reported)	1.18	1	0	0.0	0.00	1.0e+00	PROCR
Pack years of smoking	2.19	1	1	2.2	0.00	1.0e+00	JMJD1C-AS1
Impedance of whole body	2.46	30	22	48.9	0.51	3.1e-03	ACTR1A C11orf83 CADM2 CTC-498M16.2 DND1 ELOVL7 FOXO3 GPX1 INO80E JMJD1C-AS1 JUND LINC00461 LMOD1 MST1R NAT6 NEGR1 PPA2 PROCR PRUNE PTK2 RBM6 RBMS1 RGS6 RNF123 RPS26 SNX32 STAG3L5P-PVRIG2P-PILRB SYPL2 TRAIP TRIM73
Leg fat mass (left)	4.16	33	21	46.7	-0.79	2.0e-08	ACTR1A C18orf8 CADM2 CPNE3 CTC-498M16.2 EDEM3 EIF3CL FOXO3 FOXP1 GALNT16 GPX1 IFT57 IL12RB1 INO80E JUND LINC00461 LMOD1 LONRF2 METTL10 MPP6 MST1R NAT6 NEGR1 RBM6 RGS6 RNF123 RPS26 SNX32 STK24 TEX15 THEM6 TRAIP TRIM73
Arm predicted mass (left)	2.90	28	21	46.7	-0.37	4.6e-02	ACTR1A C18orf8 CADM2 CTC-498M16.2 DCAF16 EIF3CL ELOVL7 FAM160A1 FOXO3 INO80E LINC00461 LMOD1 MGAT3 MPHOSPH9 MST1R NAT6 NEGR1 PPA2 PROCR RBL2 RBM6 RNF123 RP11-864G5.3 RPS26 SNX32 TRAIP TRIM38 TRMT61A

Associations by panel

study	tissue	# hits	% hits/tests	avg chisq
GTEx	Adipose Subcutaneous	41	1.17	3.2
GTEx	Adipose Visceral Omentum	30	1.47	3.4
GTEx	Adrenal Gland	13	0.89	3.1
GTEx	Artery Aorta	44	1.48	3.3
GTEx	Artery Coronary	20	1.69	3.3
GTEx	Artery Tibial	51	1.36	3.2
GTEx	Brain Caudate basal ganglia	12	1.30	3.4
GTEx	Brain Cerebellar Hemisphere	22	1.48	3.6
GTEx	Brain Cerebellum	26	1.31	3.5
GTEx	Brain Cortex	22	2.13	3.6
GTEx	Brain Frontal Cortex BA9	16	1.73	3.7
GTEx	Brain Hippocampus	8	1.53	3.4
GTEx	Brain Hypothalamus	10	1.69	3.2
GTEx	Brain Nucleus accumbens basal ganglia	13	1.50	3.5
GTEx	Brain Putamen basal ganglia	9	1.44	3.8
GTEx	Breast Mammary Tissue	33	1.67	3.5
GTEx	Breast Mammary Tissue (Male)	12	1.01	3.2
GTEx	Breast Mammary Tissue (Female)	25	1.52	3.3
GTEx	Cells EBV-transformed lymphocytes	23	1.62	3.5
GTEx	Cells Transformed fibroblasts	55	1.31	3.2
GTEx	Colon Sigmoid	28	1.92	3.5
GTEx	Colon Transverse	32	1.55	3.3
GTEx	Esophagus Gastroesophageal Junction	26	1.80	3.6
GTEx	Esophagus Mucosa	43	1.30	3.3
GTEx	Esophagus Muscularis	44	1.36	3.4
GTEx	Heart Atrial Appendage	22	1.39	3.4
GTEx	Heart Left Ventricle	23	1.50	3.3
GTEx	Liver	10	1.39	3.2
GTEx	Lung	43	1.50	3.3
GTEx	Muscle Skeletal	37	1.28	3.3
GTEx	Nerve Tibial	53	1.23	3.2
GTEx	Ovary	19	2.09	3.6
GTEx	Pancreas	32	1.96	3.5
GTEx	Pituitary	12	1.08	3.3
GTEx	Prostate	14	1.68	3.5
GTEx	Skin Not Sun Exposed Suprapubic	34	1.38	3.4
GTEx	Skin Sun Exposed Lower leg	44	1.21	3.3
GTEx	Small Intestine Terminal Ileum	10	2.17	3.5
GTEx	Spleen	21	1.49	3.6
GTEx	Stomach	26	1.79	3.5
GTEx	Testis	40	1.27	3.3
GTEx	Thyroid	52	1.30	3.2
GTEx	Uterus	11	1.94	3.5
GTEx	Vagina	13	2.05	3.6
GTEx	Whole Blood	22	1.10	3.1
METSIM	Adipose	41	0.89	2.9
NTR	Blood	16	0.67	3.0
ROSMAP	Brain Pre-frontal Cortex	54	1.23	3.3
YFS	Blood	31	0.67	2.8
CommonMind	Brain Pre-frontal Cortex	48	0.89	2.9
The Cancer Genome Atlas	Bladder Urothelial Carcinoma	18	1.09	3.0
The Cancer Genome Atlas	Breast Invasive Carcinoma	31	0.70	2.8
The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	15	1.37	3.3
The Cancer Genome Atlas	Colon Adenocarcinoma	21	1.02	2.9
The Cancer Genome Atlas	Esophageal Carcinoma	10	1.46	3.0
The Cancer Genome Atlas	Glioblastoma Multiforme	17	1.66	3.2
The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	27	0.99	3.0
The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	33	0.81	2.9
The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	20	0.98	3.0
The Cancer Genome Atlas	Brain Lower Grade Glioma	41	0.95	3.0
The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	11	0.99	3.0
The Cancer Genome Atlas	Lung Adenocarcinoma	30	1.02	2.9
The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	29	1.16	3.0
The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	17	1.07	3.1
The Cancer Genome Atlas	Pancreatic Adenocarcinoma	21	1.26	3.1
The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	12	0.90	2.9
The Cancer Genome Atlas	Prostate Adenocarcinoma	42	0.91	2.9
The Cancer Genome Atlas	Rectum Adenocarcinoma	10	1.45	3.0
The Cancer Genome Atlas	Soft Tissue Sarcoma	12	1.12	3.1
The Cancer Genome Atlas	Skin Cutaneous Melanoma	5	0.93	3.0
The Cancer Genome Atlas	Stomach Adenocarcinoma	16	0.95	3.1
The Cancer Genome Atlas	Testicular Germ Cell Tumors	11	0.86	3.1
The Cancer Genome Atlas	Thyroid Carcinoma	46	0.89	3.0
The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	6	1.18	2.9