Best TWAS P=2.65e-08 · Best GWAS P=2.81e-07 conditioned to 0.163
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | DCP2 | 0.14 | 0.07 | lasso | 3 | 0.07 | 2.9e-06 | 5.0 | 5.4 | 6.3e-08 | 0.93 | 0.01 | 0.99 | FALSE |
2 | GTEx | Skin Sun Exposed Lower leg | DCP2 | 0.18 | 0.12 | enet | 20 | 0.16 | 5.4e-13 | -4.5 | 5.6 | 2.6e-08 | 0.76 | 0.01 | 0.99 | TRUE |
3 | GTEx | Spleen | DCP2 | 0.52 | 0.19 | enet | 22 | 0.13 | 4.0e-04 | -4.6 | 5.3 | 1.2e-07 | 0.92 | 0.01 | 0.97 | FALSE |
4 | GTEx | Thyroid | DCP2 | 0.19 | 0.19 | lasso | 2 | 0.19 | 2.2e-14 | 5.1 | 5.1 | 2.8e-07 | 1.00 | 0.00 | 0.99 | FALSE |
5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DCP2 | 0.05 | 0.01 | blup | 82 | 0.04 | 6.3e-05 | -3.9 | 5.4 | 7.1e-08 | 0.70 | 0.02 | 0.77 | FALSE |