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chr7:20,885,792-22,639,717

Best TWAS P=2.45e-10 · Best GWAS P=4.72e-10 conditioned to 0.000902

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DNAH11 0.21 0.16 enet 37 0.14 2.8e-16 5.1 -5.7 1.3e-08 0.56 0.42 0.58 FALSE
2 The Cancer Genome Atlas Bladder Urothelial Carcinoma DNAH11 0.10 0.03 blup 329 0.02 7.1e-03 4.8 -5.3 1.4e-07 0.52 0.15 0.66 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma DNAH11 0.02 0.03 lasso 2 0.02 1.4e-05 5.2 -5.4 5.6e-08 0.53 0.37 0.55 FALSE
4 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma DNAH11 0.28 0.23 enet 7 0.20 3.1e-10 5.0 -5.2 2.3e-07 0.51 0.42 0.58 FALSE
5 The Cancer Genome Atlas Glioblastoma Multiforme DNAH11 0.29 0.19 lasso 2 0.18 3.1e-06 5.2 -5.2 1.9e-07 0.50 0.32 0.61 FALSE
6 The Cancer Genome Atlas Lung Adenocarcinoma DNAH11 0.17 0.16 lasso 7 0.15 1.9e-17 5.1 -5.1 2.9e-07 0.53 0.39 0.61 FALSE
7 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DNAH11 0.17 0.14 lasso 4 0.13 1.2e-14 5.0 -5.3 1.2e-07 0.53 0.42 0.58 FALSE
8 The Cancer Genome Atlas Prostate Adenocarcinoma DNAH11 0.06 0.02 blup 331 0.03 6.4e-04 -4.5 -6.3 2.4e-10 0.54 0.05 0.80 TRUE
9 The Cancer Genome Atlas Thyroid Carcinoma DNAH11 0.21 0.06 lasso 6 0.12 2.8e-11 -5.8 -5.2 1.8e-07 0.59 0.05 0.95 FALSE