Best TWAS P=6.37e-08 · Best GWAS P=3.2e-07 conditioned to 0.000217
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | C11orf83 | 0.07 | 0.01 | blup | 24 | 0.01 | 1.0e-02 | -3.4 | 5.4 | 6.4e-08 | 0.29 | 0.00 | 0.16 | TRUE |
2 | The Cancer Genome Atlas | Rectum Adenocarcinoma | EML3 | 0.36 | 0.08 | blup | 27 | 0.19 | 3.7e-05 | -3.9 | -5.3 | 1.4e-07 | -0.72 | 0.02 | 0.42 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | EML3 | 0.11 | 0.10 | blup | 28 | 0.12 | 2.3e-11 | -4.0 | -5.2 | 2.6e-07 | -0.37 | 0.07 | 0.81 | FALSE |