Best TWAS P=6.69e-08 · Best GWAS P=2.9e-06 conditioned to 0.567
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | NPIPA1 | 0.18 | 0.03 | lasso | 4 | 0.08 | 8.3e-07 | 3.2 | -5.2 | 2.6e-07 | 0.74 | 0.01 | 0.90 | FALSE |
2 | METSIM | Adipose | RP11-1186N24.5 | 0.18 | 0.10 | enet | 24 | 0.13 | 4.6e-19 | -4.7 | -5.4 | 6.7e-08 | 0.80 | 0.00 | 0.98 | TRUE |