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chr19:35,448,803-36,956,110

Best TWAS P=5.04e-08 · Best GWAS P=1.37e-07 conditioned to 0.433

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ZBTB32 0.11 0.04 blup 443 0.04 1.5e-05 4.2 5.3 1.5e-07 -0.57 0.09 0.88 FALSE
2 GTEx Adipose Subcutaneous COX6B1 0.11 0.09 lasso 3 0.07 1.3e-06 5.2 -5.3 1.5e-07 0.93 0.00 1.00 FALSE
3 GTEx Artery Tibial COX6B1 0.13 0.08 enet 6 0.06 9.7e-06 4.8 -5.2 1.6e-07 0.93 0.01 0.99 FALSE
4 GTEx Lung C19orf55 0.11 0.03 enet 21 0.01 2.4e-02 -5.3 -5.4 8.8e-08 0.90 0.01 0.99 FALSE
5 GTEx Muscle Skeletal COX6B1 0.24 0.20 lasso 6 0.23 4.4e-22 5.2 -5.4 5.9e-08 0.96 0.00 1.00 FALSE
6 NTR Blood COX6B1 0.04 0.02 lasso 6 0.02 6.4e-08 5.2 -5.2 1.8e-07 0.96 0.01 0.99 FALSE
7 The Cancer Genome Atlas Colon Adenocarcinoma ZBTB32 0.07 0.02 lasso 4 0.05 1.2e-03 5.2 5.2 2.0e-07 -0.84 0.01 0.71 FALSE
8 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma COX6B1 0.20 0.06 lasso 2 0.06 2.9e-04 -5.3 -5.4 5.0e-08 0.91 0.00 0.99 TRUE
9 The Cancer Genome Atlas Brain Lower Grade Glioma COX6B1 0.08 0.07 enet 3 0.06 4.0e-07 -5.3 -5.2 1.6e-07 0.97 0.00 1.00 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma UPK1A 0.08 0.10 enet 5 0.10 1.9e-11 -5.3 5.1 2.8e-07 -0.97 0.00 1.00 FALSE