Best TWAS P=5.92e-09 · Best GWAS P=9.98e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | DBN1 | 0.11 | 0.13 | enet | 11 | 0.13 | 8.4e-41 | -5.7 | -5.8 | 5.9e-09 | 0.99 | 0.01 | 0.99 | TRUE |
| 2 | YFS | Blood | GRK6 | 0.18 | 0.21 | lasso | 4 | 0.21 | 5.4e-68 | -5.7 | -5.7 | 1.3e-08 | 1.00 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PRR7 | 0.07 | 0.04 | lasso | 3 | 0.05 | 2.2e-06 | 5.5 | -5.6 | 2.4e-08 | 0.96 | 0.02 | 0.97 | FALSE |