Best TWAS P=2.22e-10 · Best GWAS P=6.89e-11 conditioned to 0.00489
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | THEM6 | 0.11 | 0.03 | enet | 18 | 0.06 | 2.8e-04 | -5.25 | -5.7 | 1.0e-08 | -0.13 | 0.27 | 0.09 | TRUE |
| 2 | GTEx | Pancreas | TSNARE1 | 0.24 | 0.05 | enet | 35 | 0.10 | 6.9e-05 | -4.89 | 6.3 | 2.2e-10 | 0.61 | 0.01 | 0.95 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | TSNARE1 | 0.19 | 0.00 | blup | 105 | 0.02 | 2.6e-02 | -4.66 | 5.6 | 2.2e-08 | 0.36 | 0.01 | 0.07 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | TSNARE1 | 0.37 | 0.01 | enet | 28 | 0.09 | 2.5e-09 | 0.56 | 5.6 | 2.1e-08 | 0.46 | 0.02 | 0.80 | FALSE |