Best TWAS P=2.24e-07 · Best GWAS P=4.24e-07 conditioned to 0.21
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | POM121C | 0.08 | 0.05 | lasso | 2 | 0.04 | 1.1e-05 | 5.1 | 5.2 | 2.5e-07 | 0.99 | 0 | 0.99 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | POM121C | 0.15 | 0.06 | lasso | 5 | 0.07 | 1.2e-05 | 5.1 | 5.1 | 2.8e-07 | 0.99 | 0 | 1.00 | FALSE |
| 3 | GTEx | Esophagus Gastroesophageal Junction | STAG3L1 | 0.36 | 0.16 | lasso | 5 | 0.16 | 1.7e-06 | 5.1 | 5.2 | 2.4e-07 | 0.93 | 0 | 0.99 | FALSE |
| 4 | GTEx | Esophagus Mucosa | PMS2P3 | 0.14 | 0.15 | lasso | 2 | 0.14 | 9.7e-10 | 5.1 | 5.1 | 2.9e-07 | 1.00 | 0 | 1.00 | FALSE |
| 5 | GTEx | Lung | POM121C | 0.13 | 0.10 | lasso | 3 | 0.10 | 7.8e-08 | 5.1 | 5.1 | 2.7e-07 | 0.98 | 0 | 1.00 | FALSE |
| 6 | GTEx | Muscle Skeletal | PMS2P3 | 0.07 | 0.07 | lasso | 2 | 0.06 | 3.8e-06 | 5.1 | 5.1 | 3.1e-07 | 1.00 | 0 | 1.00 | FALSE |
| 7 | GTEx | Skin Sun Exposed Lower leg | PMS2P3 | 0.38 | 0.30 | lasso | 3 | 0.29 | 1.9e-24 | 5.1 | 5.1 | 3.1e-07 | 1.00 | 0 | 1.00 | FALSE |
| 8 | GTEx | Whole Blood | STAG3L1 | 0.08 | 0.06 | lasso | 3 | 0.07 | 2.8e-07 | 5.1 | 5.1 | 3.0e-07 | 1.00 | 0 | 1.00 | FALSE |
| 9 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | POM121C | 0.07 | 0.02 | enet | 3 | 0.04 | 5.8e-03 | 5.1 | 5.2 | 2.2e-07 | 0.85 | 0 | 0.38 | TRUE |