Best TWAS P=1.36e-08 · Best GWAS P=1.29e-10 conditioned to 0.00181
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | GRIN2A | 0.06 | 0.06 | lasso | 2 | 0.05 | 2.0e-06 | -5.6 | -5.6 | 2.7e-08 | 0.80 | 0.04 | 0.96 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | GRIN2A | 0.26 | 0.16 | lasso | 7 | 0.21 | 4.6e-12 | -5.7 | -5.6 | 1.9e-08 | 0.81 | 0.09 | 0.91 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | GRIN2A | 0.24 | 0.22 | lasso | 6 | 0.22 | 5.1e-21 | -5.6 | -5.7 | 1.4e-08 | 0.81 | 0.10 | 0.90 | TRUE |