Best TWAS P=1.03e-07 · Best GWAS P=7.42e-07 conditioned to 0.979
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue | KLC1 | 0.12 | 0.02 | enet | 26 | 0.07 | 0.00029 | 4.7 | 5.2 | 1.6e-07 | 0.81 | 0.05 | 0.94 | FALSE |
2 | GTEx | Cells EBV-transformed lymphocytes | PPP1R13B | 0.15 | 0.08 | lasso | 4 | 0.07 | 0.00217 | 4.8 | -5.3 | 1.0e-07 | -0.93 | 0.04 | 0.90 | TRUE |