Best TWAS P=5.53e-08 · Best GWAS P=7.24e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | QSOX2 | 0.10 | 0.11 | lasso | 2 | 0.10 | 1.6e-06 | -5.4 | 5.4 | 5.5e-08 | -1.00 | 0.00 | 1.00 | TRUE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | QSOX2 | 0.05 | 0.05 | enet | 4 | 0.05 | 2.7e-06 | -5.4 | 5.4 | 8.4e-08 | -0.94 | 0.00 | 1.00 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | QSOX2 | 0.08 | 0.07 | lasso | 4 | 0.08 | 1.2e-08 | -5.4 | 5.3 | 1.1e-07 | -0.92 | 0.00 | 1.00 | FALSE |
4 | The Cancer Genome Atlas | Thyroid Carcinoma | QSOX2 | 0.06 | 0.01 | blup | 32 | 0.05 | 1.6e-05 | 3.1 | 5.1 | 2.8e-07 | -0.62 | 0.01 | 0.79 | FALSE |