Best TWAS P=1.5e-09 · Best GWAS P=2.89e-09 conditioned to 0.0107
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | C14orf39 | 0.06 | 0.05 | lasso | 3 | 0.05 | 2.7e-05 | 5.0 | -6.0 | 1.5e-09 | -0.67 | 0.11 | 0.88 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | C14orf39 | 0.02 | 0.02 | blup | 37 | 0.02 | 4.2e-03 | 5.3 | -5.6 | 2.1e-08 | -0.55 | 0.02 | 0.84 | FALSE |
| 3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | C14orf39 | 0.08 | 0.05 | blup | 37 | 0.05 | 4.2e-03 | 4.9 | -5.4 | 6.9e-08 | -0.51 | 0.03 | 0.79 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | C14orf39 | 0.08 | 0.09 | blup | 37 | 0.11 | 1.8e-11 | 5.0 | -5.5 | 4.1e-08 | -0.51 | 0.02 | 0.97 | FALSE |