Best TWAS P=3.34e-08 · Best GWAS P=9.02e-07 conditioned to 0.918
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | FES | 0.28 | 0.17 | enet | 21 | 0.20 | 2.8e-15 | 4.2 | -5.2 | 2.0e-07 | -0.91 | 0.01 | 0.98 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FES | 0.06 | 0.05 | blup | 46 | 0.07 | 7.4e-14 | 4.2 | -5.5 | 3.3e-08 | -0.90 | 0.01 | 0.98 | TRUE |