TWAS hub - FES

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.2150	0.0710	1.1e-03	0.093	NA	0.021	NA	0.050	1.6e-05	NA	2.8e-02	NA	1.3e-03
2	GTEx	Artery Tibial	0.1576	0.0505	8.7e-04	0.039	NA	0.044	NA	0.054	4.5e-04	NA	2.2e-04	NA	4.7e-05
3	GTEx	Cells Transformed fibroblasts	0.2790	0.0500	1.2e-08	0.168	NA	0.204	NA	0.202	1.3e-12	NA	2.8e-15	NA	4.3e-15
4	GTEx	Lung	0.2368	0.0603	5.6e-05	0.066	NA	0.029	NA	0.055	9.4e-06	NA	2.5e-03	NA	5.1e-05
5	GTEx	Skin Sun Exposed Lower leg	0.0930	0.0360	5.0e-03	0.042	NA	0.039	NA	0.044	2.0e-04	NA	3.2e-04	NA	1.4e-04
6	GTEx	Thyroid	0.3310	0.0610	2.7e-08	0.187	NA	0.182	NA	0.185	2.8e-14	NA	6.4e-14	NA	4.3e-14
7	METSIM	Adipose	0.0848	0.0296	3.7e-04	0.063	0.034	0.049	0.045	0.049	1.1e-09	5.8e-06	6.9e-08	2.0e-07	6.8e-08
8	YFS	Blood	0.3139	0.0373	0.0e+00	0.109	0.204	0.215	0.203	0.188	8.0e-34	8.0e-65	1.2e-68	3.2e-64	2.1e-59
9	TCGA	Bladder Urothelial Carcinoma	0.0600	0.0290	1.5e-04	0.046	0.055	0.038	NA	0.043	8.7e-05	1.9e-05	3.3e-04	NA	1.5e-04
10	TCGA	Breast Invasive Carcinoma	0.0571	0.0221	1.5e-12	0.054	0.068	0.065	NA	0.062	2.7e-11	7.5e-14	3.7e-13	NA	1.1e-12
11	TCGA	Cervical Squamous Cell Carcinoma	0.0640	0.0370	8.4e-03	0.017	0.024	0.003	NA	0.011	4.6e-02	2.4e-02	2.2e-01	NA	8.8e-02
12	TCGA	Colon Adenocarcinoma	0.0830	0.0510	2.5e-03	0.068	0.056	0.056	NA	0.049	8.6e-05	3.4e-04	3.8e-04	NA	8.3e-04
13	TCGA	Glioblastoma Multiforme	0.1230	0.0670	6.9e-03	0.064	0.051	0.063	NA	0.051	5.4e-03	1.2e-02	5.7e-03	NA	1.2e-02
14	TCGA	Head and Neck Squamous Cell Carcinoma	0.0559	0.0234	2.5e-06	0.029	0.046	0.033	NA	0.028	3.2e-04	5.6e-06	1.3e-04	NA	3.4e-04
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.0978	0.0420	1.6e-06	0.065	0.037	0.049	NA	0.042	7.3e-08	4.4e-05	2.9e-06	NA	1.6e-05
16	TCGA	Lung Adenocarcinoma	0.0492	0.0221	2.5e-05	0.042	0.033	0.037	NA	0.039	1.0e-05	8.2e-05	3.6e-05	NA	2.2e-05
17	TCGA	Lung Squamous Cell Carcinoma	0.0760	0.0292	2.6e-08	0.074	0.076	0.077	NA	0.075	9.4e-09	5.9e-09	4.2e-09	NA	7.5e-09
18	TCGA	Ovarian Serous Cystadenocarcinoma	0.1350	0.0480	3.1e-08	0.155	0.119	0.139	NA	0.144	1.2e-10	2.2e-08	1.2e-09	NA	6.1e-10
19	TCGA	Prostate Adenocarcinoma	0.1188	0.0470	1.5e-08	0.088	0.074	0.074	NA	0.084	1.7e-09	3.2e-08	3.5e-08	NA	4.1e-09
20	TCGA	Stomach Adenocarcinoma	0.0430	0.0230	6.5e-03	0.006	0.018	-0.004	NA	-0.001	1.1e-01	1.7e-02	9.5e-01	NA	4.2e-01
21	TCGA	Testicular Germ Cell Tumors	0.3190	0.0960	3.2e-07	0.263	0.208	0.239	NA	0.252	7.7e-10	6.9e-08	5.7e-09	NA	2.0e-09
22	TCGA	Thyroid Carcinoma	0.2960	0.0720	0.0e+00	0.305	0.286	0.247	NA	0.318	4.3e-30	4.5e-28	6.6e-24	NA	1.3e-31

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22
Systolic Blood Pressure	51.0	255.1	313.3	-16.0	-16.6	-17.7	-16.8	-14.6	-15.4	-14.2	-14.0	-15.7	-16.9	-14.3	-16.0	-16.4	-15.3	-15.6	-17.3	-16.5	-16.0	-17.6	-14.1	-16.0	-17.5
Vascular/heart problems diagnosed by doctor	50.6	138.0	187.7	11.4	11.9	12.6	12.3	10.0	11.1	10.9	11.0	10.9	13.7	11.4	11.8	11.1	11.2	11.3	12.6	12.2	11.5	12.8	11.6	11.7	12.8
High blood pressure (mother)	48.5	68.0	91.7	-9.1	-8.4	-8.6	-8.5	-8.3	-8.7	-8.5	-5.9	-7.5	-9.6	-7.6	-7.4	-6.5	-8.1	-6.6	-8.8	-8.8	-9.0	-9.1	-8.0	-8.4	-8.7
Hypertension (Self-reported)	45.1	125.4	171.6	-11.0	-11.3	-11.9	-11.8	-9.6	-10.7	-10.5	-10.6	-10.2	-13.1	-11.0	-11.2	-10.5	-10.5	-10.6	-11.9	-11.6	-11.0	-12.3	-11.1	-11.1	-12.2
High blood pressure	44.7	124.7	169.0	-10.9	-11.3	-11.9	-11.8	-9.6	-10.6	-10.4	-10.4	-10.2	-13.0	-11.0	-11.3	-10.5	-10.5	-10.6	-11.9	-11.6	-11.0	-12.2	-11.0	-11.2	-12.2
Systolic blood pressure, automated reading	38.8	112.8	148.8	-10.5	-10.9	-11.6	-10.8	-10.2	-10.1	-9.4	-9.5	-10.6	-12.2	-9.6	-10.4	-10.0	-10.9	-10.2	-11.4	-10.7	-10.6	-11.4	-9.5	-10.9	-11.7
Medication: Blood pressure	38.2	67.4	90.2	-8.3	-8.3	-8.8	-8.8	-7.3	-8.2	-8.1	-6.8	-7.3	-9.5	-8.3	-7.9	-7.4	-7.8	-7.3	-8.7	-8.7	-8.3	-8.9	-8.4	-8.2	-8.8
Cardiovascular Disease	37.8	124.9	158.1	-11.2	-11.7	-12.0	-12.0	-10.1	-10.9	-10.4	-10.2	-10.0	-11.9	-10.7	-10.9	-11.1	-9.8	-10.4	-12.0	-11.7	-11.3	-12.6	-10.6	-11.3	-12.3
Medication for cholesterol, blood pressure or diabetes	36.4	60.2	78.4	8.0	8.2	8.3	8.3	7.2	7.9	7.6	6.3	6.6	8.9	8.0	7.4	6.7	7.2	6.6	8.2	8.3	8.0	8.4	7.9	7.9	8.3
Illnesses of father: High blood pressure	33.5	41.5	55.6	-6.6	-6.3	-6.9	-6.9	-6.0	-6.6	-6.2	-4.4	-6.2	-7.5	-6.4	-5.8	-5.6	-6.9	-5.5	-6.9	-7.2	-6.7	-6.7	-6.7	-6.4	-6.6
Medication: Blood pressure	31.4	59.8	85.3	-7.3	-7.8	-8.4	-8.0	-6.8	-7.2	-7.0	-7.0	-7.3	-9.2	-7.4	-8.3	-7.5	-7.4	-8.2	-8.3	-7.9	-7.3	-8.0	-7.5	-7.5	-8.3
Illnesses of father: Heart disease	31.3	43.4	55.7	-6.8	-6.7	-7.0	-7.0	-5.9	-6.4	-6.5	-5.8	-5.7	-7.5	-6.7	-6.6	-6.1	-6.3	-6.0	-7.0	-6.8	-6.6	-7.0	-6.9	-6.4	-7.0
Diastolic blood pressure, automated reading	30.0	93.1	121.0	-9.8	-10.3	-10.1	-10.2	-9.4	-9.5	-8.8	-7.5	-9.9	-11.0	-8.5	-8.7	-8.8	-10.2	-8.4	-10.3	-9.7	-9.9	-10.8	-8.7	-10.1	-10.7
Illnesses of father: None of the above (group 1)	29.6	36.5	56.5	5.7	6.3	6.6	6.2	4.9	5.3	5.3	4.9	4.9	6.9	7.2	6.1	5.9	5.7	6.0	6.3	6.2	5.6	6.2	7.5	5.9	6.5
Illnesses of mother	28.7	35.4	48.7	7.0	5.8	6.1	6.1	6.4	6.7	6.4	3.2	4.8	6.6	5.9	5.2	4.3	5.5	4.0	6.3	6.5	6.9	6.5	5.7	6.8	6.5
Medication: Atenolol	26.9	33.7	46.8	-5.7	-5.4	-6.5	-6.0	-5.1	-5.5	-5.4	-5.0	-5.6	-6.8	-5.4	-5.9	-5.6	-5.8	-5.9	-6.3	-6.0	-5.7	-6.4	-5.5	-5.6	-6.3
Angina (self-reported)	24.7	32.5	46.9	-5.5	-5.3	-6.3	-5.7	-4.8	-5.4	-5.3	-5.0	-5.7	-6.8	-5.5	-5.8	-5.3	-5.9	-5.7	-6.1	-5.7	-5.6	-6.0	-5.7	-5.7	-6.2
Angina	24.3	31.9	45.8	-5.4	-5.2	-6.2	-5.7	-4.7	-5.2	-5.3	-5.1	-5.7	-6.8	-5.5	-5.7	-5.3	-5.8	-5.7	-6.1	-5.5	-5.6	-6.0	-5.7	-5.6	-6.1
Birth weight of first child	24.1	43.8	62.9	5.8	5.8	7.3	6.2	5.8	5.6	5.7	6.8	7.5	7.9	6.0	6.3	6.6	7.9	7.1	7.0	6.4	6.0	6.7	7.3	6.0	6.9
High blood pressure (siblings)	21.1	30.4	38.0	-5.8	-5.9	-5.7	-5.5	-5.7	-5.5	-5.3	-5.2	-5.5	-6.2	-4.7	-5.0	-5.0	-5.7	-4.6	-5.9	-5.4	-5.8	-6.1	-4.9	-5.7	-5.9
Medication: Aspirin	19.6	25.6	34.6	-5.2	-5.2	-5.5	-5.5	-4.4	-5.0	-4.6	-4.6	-4.7	-5.9	-5.2	-4.8	-4.4	-4.8	-4.5	-5.3	-4.8	-5.2	-5.5	-5.4	-5.0	-5.3
Medication: Amlodipine	19.5	27.4	40.2	-4.7	-5.5	-5.6	-5.4	-4.4	-4.8	-4.7	-4.8	-5.3	-6.3	-5.2	-4.9	-4.8	-5.5	-5.2	-5.5	-5.4	-4.8	-5.6	-6.1	-4.6	-5.4
Medication: Cholesterol lowering	18.2	28.4	37.6	-5.6	-5.4	-5.8	-5.4	-5.4	-5.5	-5.3	-3.9	-4.3	-6.1	-5.5	-5.2	-4.4	-4.7	-4.5	-5.6	-5.8	-5.6	-5.6	-5.6	-5.6	-5.7
Medication: Aspirin	17.4	23.0	31.6	-4.8	-4.6	-5.3	-5.1	-3.9	-4.7	-4.4	-4.5	-4.5	-5.6	-4.9	-4.6	-4.3	-4.7	-4.4	-5.1	-4.7	-4.8	-5.2	-5.3	-4.7	-5.0
Schizophrenia (2018)	16.7	34.7	55.4	5.7	5.1	6.2	5.9	4.6	5.4	5.0	2.9	6.2	7.4	6.5	6.2	5.8	6.8	6.3	6.1	5.9	5.3	5.7	7.4	5.6	6.1
Heart attack/myocardial infarction (self-reported)	16.6	21.4	30.4	-4.5	-4.4	-5.2	-4.4	-4.0	-4.2	-4.4	-4.3	-4.2	-5.5	-4.6	-4.9	-4.4	-4.4	-4.6	-4.8	-4.9	-4.5	-4.8	-5.0	-4.5	-4.9
Schizophrenia (2014)	16.5	36.5	54.3	5.9	5.2	6.4	5.6	5.0	5.6	5.3	3.6	5.6	7.4	6.7	6.6	6.1	6.4	6.4	6.5	6.5	5.7	5.8	7.3	5.8	6.3
Heart attack	16.5	21.1	30.5	-4.3	-4.3	-5.2	-4.4	-3.8	-4.0	-4.2	-4.4	-4.3	-5.5	-4.5	-5.0	-4.5	-4.5	-4.9	-4.9	-4.8	-4.3	-4.7	-4.9	-4.3	-4.9
Father’s age at death	16.3	21.8	28.1	4.4	5.0	5.2	4.7	4.5	4.0	3.8	4.8	4.2	5.3	4.1	4.8	4.7	4.2	4.8	5.3	5.0	4.4	5.2	4.3	4.5	5.1
Bipolar Disorder or Schizophrenia	15.8	38.6	61.3	5.8	5.2	6.7	6.1	4.7	5.5	5.0	3.5	6.4	7.8	6.6	6.6	6.4	7.0	7.1	6.7	6.5	5.5	6.1	7.5	5.8	6.5
Medication: Simvastatin	15.8	23.2	30.5	-5.0	-5.3	-5.2	-4.9	-4.0	-4.6	-4.6	-4.6	-4.1	-5.5	-4.4	-4.5	-4.0	-4.3	-4.1	-5.1	-5.2	-5.0	-5.3	-4.7	-5.4	-5.5
Illnesses of siblings	15.0	21.0	27.0	4.9	5.0	4.5	4.8	4.8	4.6	4.6	4.7	4.5	5.1	4.0	3.6	3.6	4.6	3.3	4.7	4.7	4.9	5.2	4.4	4.9	4.9
Medication: Bendroflumethiazide	14.6	22.1	28.7	-4.1	-4.9	-5.1	-4.8	-4.8	-4.3	-4.2	-3.7	-4.1	-5.4	-4.8	-5.4	-4.8	-4.3	-5.1	-5.1	-4.7	-4.3	-4.8	-4.6	-4.6	-5.1
Heart disease (siblings)	14.6	18.0	23.4	-4.3	-4.4	-4.6	-4.7	-3.3	-4.2	-4.1	-4.6	-4.1	-4.8	-3.6	-3.6	-3.7	-4.2	-3.5	-4.4	-4.6	-4.4	-4.7	-3.8	-4.4	-4.6
Birth weight	12.7	27.5	38.3	4.8	5.0	6.2	4.7	4.5	4.3	4.2	5.6	5.5	6.1	5.1	5.1	5.2	5.8	5.6	5.6	5.3	4.8	5.4	5.7	4.8	5.4
Medication: Ramipril	11.3	14.5	21.5	-3.7	-4.1	-4.3	-4.2	-3.1	-3.9	-4.0	-2.3	-3.4	-4.6	-4.1	-3.7	-3.1	-3.7	-3.2	-3.7	-4.0	-3.8	-4.0	-4.6	-3.6	-3.9
Sensitivity / hurt feelings	10.0	17.1	27.8	4.2	3.5	4.4	4.6	3.3	4.2	3.3	2.0	3.7	5.3	4.6	5.1	3.9	4.0	4.8	4.5	4.5	3.9	4.0	3.7	3.8	4.3
Medication for cholesterol	9.8	14.9	23.0	2.9	3.8	4.2	3.8	2.0	3.1	3.2	4.4	3.8	4.8	3.9	4.4	4.3	3.8	4.7	4.0	4.0	3.1	3.9	4.2	3.3	4.1
Breastfed as a baby	9.3	11.6	16.3	-3.6	-3.6	-3.5	-3.4	-4.0	-3.5	-3.2	-2.4	-3.0	-3.8	-3.2	-3.4	-3.3	-3.0	-3.1	-3.7	-3.5	-3.5	-3.8	-2.5	-3.4	-3.7
Heart disease (mother)	9.0	11.0	14.5	-3.7	-3.0	-3.4	-3.2	-3.5	-3.5	-3.5	-2.8	-2.5	-3.5	-3.3	-3.1	-2.8	-3.0	-2.4	-3.6	-3.6	-3.8	-3.6	-3.3	-3.8	-3.6
Pulse wave peak to peak time	8.1	9.6	14.4	2.8	3.2	3.5	2.8	2.3	2.4	2.4	3.0	3.0	3.8	2.8	3.3	3.2	2.9	3.5	3.3	3.1	2.6	3.4	3.2	3.2	3.5
Medication: Lisinopril	7.9	10.2	14.5	-3.1	-3.6	-3.5	-3.8	-2.4	-2.8	-2.9	-3.8	-2.1	-3.6	-3.7	-3.6	-2.9	-2.2	-3.4	-3.5	-3.1	-2.9	-3.4	-3.4	-2.6	-3.2
Handedness (chirality/laterality): Left-handed	7.8	9.3	17.3	2.7	3.0	3.5	3.1	2.1	2.6	2.2	2.4	2.7	3.8	3.1	3.9	3.6	2.4	4.2	3.5	3.4	2.6	3.0	2.2	2.7	3.3
Number of treatments/medications taken	7.7	13.9	27.6	-3.7	-4.0	-3.6	-4.1	-3.2	-3.9	-4.3	-3.3	-2.9	-4.2	-4.3	-3.1	-2.9	-3.4	-2.3	-3.4	-3.8	-3.8	-4.0	-5.2	-3.8	-3.8
Pulse wave Arterial Stiffness index	7.7	8.9	13.3	-2.7	-3.2	-3.4	-2.9	-2.3	-2.3	-2.3	-3.0	-2.8	-3.7	-2.8	-3.2	-3.1	-2.7	-3.3	-3.2	-3.1	-2.5	-3.4	-3.1	-3.0	-3.4
Alcohol usually taken with meals	7.6	12.3	18.1	-3.5	-3.2	-3.8	-3.5	-2.9	-3.4	-2.9	-2.5	-3.3	-4.2	-3.9	-3.9	-3.5	-3.5	-4.2	-4.0	-3.6	-3.3	-3.5	-3.5	-3.1	-3.6
Breast Cancer	7.5	18.2	31.4	-4.2	-2.8	-4.7	-4.0	-3.6	-4.2	-4.0	-1.8	-4.6	-4.5	-4.8	-4.7	-4.7	-5.1	-4.8	-4.6	-4.2	-4.1	-3.7	-5.6	-3.6	-4.0
Number of incorrect matches in round	7.4	12.3	19.7	3.4	2.9	3.6	3.3	3.1	3.4	2.5	0.4	4.1	4.4	3.5	3.9	3.8	4.0	4.4	4.0	4.0	3.3	3.2	3.0	3.4	3.7
Ever had stillbirth, spontaneous miscarriage or termination	7.4	7.9	12.5	3.5	3.4	2.8	3.0	3.1	3.4	3.4	1.8	1.9	2.9	2.1	2.8	2.0	2.1	1.8	3.0	2.9	3.5	3.1	1.2	3.2	3.0
Smoking Status	7.3	17.4	26.8	4.3	5.2	4.2	4.6	4.9	4.3	4.1	3.7	4.0	4.4	3.4	4.0	3.8	3.9	3.5	4.3	3.9	4.4	4.7	3.2	4.2	4.5
Risk taking	6.9	10.1	16.4	2.7	2.5	3.5	2.8	2.9	2.6	2.2	2.7	3.3	3.8	3.3	3.6	3.6	3.6	4.0	3.6	3.1	2.7	3.1	3.6	2.7	3.3
Age started oral contraceptive pill	6.8	8.5	12.5	-3.1	-3.2	-3.2	-3.0	-2.8	-2.8	-2.3	-2.8	-2.7	-3.3	-2.5	-2.8	-2.7	-2.4	-2.8	-3.2	-2.9	-2.9	-3.3	-1.7	-3.4	-3.5
Severe depression (siblings)	6.6	7.3	12.1	2.7	2.3	3.0	2.8	2.5	2.6	2.0	1.6	1.6	3.0	3.3	3.5	2.9	1.6	3.0	3.2	3.1	2.8	3.0	1.9	2.8	3.1
Lung cancer (father)	6.6	7.7	11.4	3.0	3.4	3.0	3.0	2.9	2.9	2.7	2.4	2.6	3.2	2.5	2.7	2.5	2.6	2.4	2.8	2.6	3.0	3.1	2.1	2.7	2.9
Headache pain in last month	6.3	10.9	14.8	3.2	3.4	3.4	3.3	3.1	3.0	2.7	3.4	3.3	3.8	2.8	3.2	3.1	3.4	3.2	3.6	3.5	3.1	3.5	3.0	3.5	3.7
High cholesterol (Self-reported)	6.2	11.0	16.0	-3.6	-3.2	-3.7	-2.9	-4.0	-3.4	-3.1	-2.7	-2.4	-3.5	-3.3	-3.3	-2.9	-2.5	-2.6	-3.6	-3.5	-3.7	-3.5	-2.9	-4.0	-3.8
Allergy	6.1	13.9	20.4	-3.3	-2.9	-4.4	-4.0	-3.8	-3.7	-3.0	-1.4	-4.0	-4.5	-3.5	-4.1	-4.0	-4.1	-4.5	-4.2	-3.9	-3.5	-3.5	-2.8	-3.6	-4.0
Ever smoked	6.0	10.5	14.2	3.1	3.4	3.4	3.7	3.2	3.2	3.0	3.0	2.2	3.7	3.8	3.5	2.9	2.2	3.0	3.3	3.1	3.2	3.4	3.7	3.1	3.4
Ovarian Cancer	5.8	7.7	13.2	-2.8	-3.2	-2.9	-2.6	-2.9	-2.8	-2.9	0.1	-3.0	-3.1	-2.6	-2.3	-2.4	-3.1	-2.2	-2.7	-2.8	-2.9	-3.1	-3.6	-2.5	-2.7
Number of live births	5.6	8.0	13.2	2.9	2.7	3.3	3.1	3.1	3.1	2.7	1.0	1.6	3.3	3.2	3.6	2.4	1.7	3.2	3.1	3.1	3.0	2.7	2.1	2.8	3.0
Mean time to correctly identify matches	5.6	10.7	14.6	3.1	3.1	3.8	3.1	3.1	3.2	2.9	2.4	3.1	3.8	3.0	3.3	3.1	3.3	3.3	3.6	3.6	3.4	3.3	3.1	3.3	3.5
Blood White Count	5.4	40.4	54.8	-5.8	-6.3	-7.4	-6.8	-5.3	-5.9	-5.9	-7.2	-5.4	-6.5	-6.1	-7.3	-7.1	-5.2	-6.8	-6.7	-6.4	-5.9	-6.5	-6.0	-5.9	-6.7
Respiratory disease	5.4	12.1	16.1	3.6	2.8	3.8	3.5	3.2	3.9	3.0	2.0	3.8	3.7	2.7	3.9	3.8	3.9	3.7	4.0	3.5	3.7	3.4	1.6	3.7	3.9
Mineral and other dietary supplements	5.4	7.2	13.5	2.1	2.5	2.6	2.8	2.5	2.5	2.4	1.3	3.2	3.4	2.8	2.5	2.9	3.1	2.9	2.6	2.4	2.3	2.7	3.7	2.1	2.6
Allergy or Eczema	5.1	13.4	27.1	3.4	3.4	3.9	4.5	5.2	3.7	3.1	0.4	3.0	3.9	4.2	3.9	3.9	3.1	3.6	3.8	3.7	3.5	3.7	3.3	3.5	3.8
Impedance of leg (right)	5.1	24.9	33.5	-5.1	-4.7	-5.5	-5.0	-3.9	-5.0	-4.3	-3.3	-5.0	-5.8	-4.4	-5.6	-5.2	-5.5	-5.4	-5.6	-5.3	-5.1	-5.0	-3.7	-5.1	-5.5
Impedance of leg (left)	5.1	24.6	33.3	-5.0	-4.5	-5.5	-4.8	-3.8	-4.8	-4.3	-3.3	-4.9	-5.8	-4.5	-5.8	-5.3	-5.3	-5.5	-5.6	-5.0	-5.0	-5.0	-3.8	-5.1	-5.5
Medication: Atorvastatin	5.1	6.4	8.6	-2.2	-2.7	-2.8	-2.4	-2.5	-2.2	-2.0	-2.4	-2.4	-2.9	-2.5	-2.7	-2.7	-2.5	-2.9	-2.8	-2.6	-2.2	-2.6	-2.6	-2.0	-2.5
Mean Putamen Volume	5.0	5.7	8.0	2.2	1.8	2.4	2.6	1.8	2.4	2.1	1.8	2.2	2.7	2.7	2.8	2.1	2.7	2.7	2.4	2.8	2.3	1.9	2.7	2.2	2.3
Crohns Disease (2012)	4.9	7.9	15.1	-3.0	-3.9	-2.6	-3.1	-2.6	-3.2	-3.0	-1.5	-2.7	-3.1	-2.4	-2.3	-2.1	-3.0	-1.8	-2.9	-2.8	-3.3	-3.2	-2.3	-3.1	-3.0
Crohns Disease (2017)	4.7	10.2	20.3	-3.7	-4.5	-3.2	-3.4	-2.9	-3.6	-3.1	-2.8	-3.0	-3.3	-2.5	-2.8	-2.5	-3.0	-2.5	-3.5	-3.1	-3.6	-3.7	-2.5	-3.1	-3.2
Current tobacco smoking	4.7	7.7	12.3	2.9	3.5	2.7	3.3	3.1	3.0	2.7	1.4	2.2	3.2	2.8	2.7	2.1	2.2	2.4	2.9	2.8	2.9	3.2	2.5	2.8	3.1
Hair/balding pattern: Pattern 4	4.6	11.2	15.5	-3.6	-2.9	-3.6	-3.2	-2.2	-3.9	-3.5	-2.1	-2.9	-3.9	-3.7	-3.9	-2.9	-3.6	-3.3	-3.7	-3.7	-3.7	-2.8	-3.1	-3.3	-3.3
Irritable Bowel Disease (IBD)	4.5	10.8	23.8	-3.6	-4.9	-3.5	-3.6	-3.3	-3.5	-2.8	-3.0	-2.7	-3.2	-2.6	-3.1	-2.8	-2.7	-2.7	-3.5	-3.4	-3.5	-3.8	-2.7	-3.1	-3.3
Hand grip strength (left)	4.5	12.0	18.2	3.4	2.4	4.3	3.1	2.2	3.3	3.2	3.8	2.7	4.2	3.5	4.0	3.3	2.9	3.8	3.8	4.0	3.3	3.1	3.2	3.9	3.9
Chronic bronchitis/emphysema (father)	4.5	5.3	9.2	2.0	1.8	2.5	2.1	1.4	2.2	2.1	2.0	2.4	2.9	1.9	2.9	2.5	2.5	3.0	2.6	2.6	2.1	2.0	2.0	1.8	2.3
Bipolar Disorder (2018)	4.4	6.9	12.6	2.2	2.0	3.0	2.4	1.8	2.1	1.8	1.8	2.6	3.4	2.5	3.0	3.0	2.6	3.5	3.1	3.0	2.2	2.6	2.8	2.5	2.9
Supplements: Fish oil (including cod liver oil)	4.4	5.8	11.2	-1.8	-2.1	-2.4	-2.3	-2.3	-2.1	-2.0	-1.4	-2.6	-3.1	-2.8	-2.5	-2.5	-2.7	-2.9	-2.4	-2.5	-2.0	-2.2	-3.4	-1.9	-2.3
Hayfever, allergic rhinitis or eczema	4.3	9.3	14.8	2.5	2.4	3.6	3.4	3.9	2.8	2.4	0.3	2.7	3.5	3.3	3.5	3.4	3.0	3.6	3.3	3.4	2.7	2.8	2.6	3.0	3.3
Smoking status: Current	4.3	6.8	11.1	2.8	3.3	2.5	3.1	2.8	2.8	2.5	1.3	2.1	3.0	2.6	2.5	1.9	2.1	2.2	2.7	2.6	2.8	3.0	2.4	2.6	2.8
Number of self-reported non-cancer illnesses	4.3	7.5	12.4	-3.1	-2.8	-2.5	-2.5	-3.3	-3.0	-3.4	-3.0	-1.0	-2.6	-3.1	-2.1	-1.8	-1.5	-0.8	-2.5	-3.0	-3.1	-3.1	-3.5	-3.3	-2.9
Major Depression (MDD)	4.2	5.1	20.3	4.1	3.2	4.5	4.1	3.5	4.4	0.0	4.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Past tobacco smoking	4.2	7.7	10.2	-2.7	-2.9	-3.0	-3.0	-3.0	-2.6	-2.2	-2.4	-2.4	-3.2	-2.7	-3.0	-2.7	-2.3	-2.8	-3.1	-2.6	-2.8	-3.1	-2.5	-2.8	-3.1
Asthma	4.2	8.3	12.0	2.9	2.1	3.3	2.9	2.7	3.4	2.8	1.5	3.4	3.3	2.1	2.9	2.8	3.5	3.1	3.3	2.8	3.0	2.7	1.4	3.0	3.1
Asthma (self-reported)	4.1	8.3	11.2	2.9	2.1	3.3	2.8	2.7	3.3	2.8	1.6	3.2	3.3	2.2	3.0	2.9	3.4	3.1	3.3	2.7	3.0	2.7	1.4	3.0	3.1
Ulcerative Colitis	4.0	5.7	8.4	-2.5	-2.9	-2.8	-2.4	-2.5	-2.2	-1.9	-2.9	-1.6	-2.6	-2.4	-2.4	-2.0	-1.8	-2.1	-2.6	-2.5	-2.4	-2.6	-2.4	-2.2	-2.4
Chronic bronchitis/emphysema (mother)	4.0	4.6	7.2	2.1	2.7	2.3	2.3	1.7	2.1	1.8	1.8	2.1	2.4	1.7	2.5	2.2	2.2	2.3	2.4	2.2	2.2	2.2	1.3	2.0	2.3
Pack years of smoking	4.0	5.9	8.1	2.8	2.7	2.2	2.8	1.7	2.8	2.8	1.2	2.8	2.9	2.1	2.2	2.1	2.7	2.1	2.4	2.0	2.7	2.6	1.7	2.5	2.6
Neuroticism	3.9	9.4	21.8	2.7	2.6	3.3	3.1	2.6	2.9	2.1	2.1	2.2	3.3	3.6	4.7	4.2	2.3	4.3	3.3	3.3	2.6	2.5	2.1	2.7	3.2
Reaction Time	3.8	7.2	9.7	2.6	2.5	3.1	2.2	2.5	2.4	2.2	2.4	2.7	2.8	2.2	2.8	3.0	2.6	3.0	3.1	3.0	2.7	2.8	2.4	2.7	2.9
Prostate Cancer	3.8	5.3	7.9	2.3	2.0	2.8	2.0	1.7	2.1	2.0	0.9	2.2	2.4	2.2	2.7	2.8	2.1	2.7	2.6	2.3	2.3	2.2	1.8	2.7	2.7
Maternal smoking around birth	3.8	5.4	8.0	2.5	2.2	2.5	2.0	2.7	2.1	1.9	2.0	2.4	2.5	1.4	2.3	2.4	2.2	2.2	2.7	2.4	2.6	2.6	1.3	2.8	2.8
Had menopause	3.6	4.5	8.3	-2.4	-2.9	-1.9	-2.0	-1.9	-2.2	-2.3	-2.8	-2.0	-2.3	-1.5	-1.5	-1.3	-2.2	-1.2	-1.9	-2.2	-2.2	-2.1	-1.7	-2.7	-2.4
Mood swings	3.6	6.4	9.2	2.6	2.6	2.6	3.0	2.5	2.4	1.6	1.9	2.0	2.9	2.9	3.0	2.6	1.9	3.0	2.9	2.5	2.4	2.7	1.7	2.6	2.9
Irritability	3.6	6.0	8.5	2.5	2.2	2.6	2.3	2.7	2.3	1.2	1.2	1.9	2.8	2.9	2.9	2.6	1.9	2.9	2.8	2.5	2.3	2.5	2.2	2.7	2.9
Neuroticism (Nagel 2018)	3.4	8.1	17.2	2.7	2.7	3.0	3.1	2.5	2.9	1.9	1.7	1.5	3.3	3.9	4.1	3.3	1.7	3.9	3.2	3.2	2.5	2.4	2.0	2.2	2.8
Pack years adult smoking proportion	3.3	5.1	7.0	2.6	2.6	2.1	2.6	1.8	2.6	2.6	1.0	2.5	2.6	2.0	2.1	2.0	2.4	2.0	2.2	1.9	2.5	2.4	1.4	2.3	2.5
Pain experienced in last month	3.3	5.6	9.9	-2.7	-2.8	-2.6	-2.8	-1.8	-2.4	-2.6	-3.1	-2.1	-2.5	-1.3	-2.3	-1.8	-2.1	-2.0	-2.4	-2.3	-2.6	-2.5	-0.6	-2.5	-2.6
Supplements: Vitamin C	3.2	3.8	8.6	-1.7	-0.6	-1.8	-1.9	-1.4	-1.9	-2.1	-1.1	-1.6	-2.4	-2.6	-2.5	-2.0	-2.2	-2.1	-1.8	-2.0	-1.8	-1.5	-2.9	-1.7	-1.8
Frequency of depressed mood in last 2 weeks	3.1	4.3	7.1	1.9	2.4	2.1	2.4	2.0	2.1	1.5	2.7	1.9	2.5	1.9	2.2	1.7	2.0	2.0	2.0	2.3	1.9	1.9	1.4	2.1	2.1
Age at First Birth	3.0	4.4	7.7	-1.8	-1.9	-2.3	-2.5	-1.5	-1.9	-2.0	-1.4	-2.3	-2.1	-1.5	-2.6	-2.7	-2.0	-2.8	-2.4	-1.9	-2.0	-2.2	-0.9	-2.0	-2.3
Lupus	3.0	4.6	6.5	2.0	1.5	2.5	2.5	2.3	2.2	1.9	1.8	2.3	2.6	1.9	2.2	2.1	2.3	2.1	2.2	2.2	2.1	2.3	1.9	1.9	2.1
Coronary Artery Disease (CAD)	2.9	3.4	12.2	-3.1	-2.9	-3.3	-3.0	-2.9	-3.1	-3.5	-2.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Depressed Affect (Nagel 2018)	2.8	5.9	11.9	2.5	2.5	2.5	2.8	2.2	2.8	2.3	1.4	1.4	2.7	2.9	3.4	2.6	1.7	2.8	2.6	2.7	2.4	2.1	1.4	2.1	2.4
Leg predicted mass (right)	2.7	14.4	20.6	3.8	3.3	4.3	3.2	2.4	3.4	3.5	3.6	4.3	4.5	3.3	4.2	4.0	4.5	4.4	4.2	3.7	3.6	3.5	3.4	3.7	4.0
Eye problems/disorders: Diabetes related eye disease	2.6	2.9	7.3	-1.6	-1.3	-1.7	-1.3	-0.9	-2.0	-2.0	-0.3	-1.7	-1.9	-1.7	-1.9	-1.7	-2.7	-1.4	-1.5	-2.2	-1.7	-0.8	-2.0	-1.6	-1.5
Number of children fathered	2.6	2.9	4.3	1.9	1.7	2.0	2.0	1.3	1.9	1.5	1.1	1.6	2.1	1.2	1.8	1.5	1.5	1.5	1.9	1.9	1.9	2.1	0.8	1.8	1.9
Leg fat-free mass (right)	2.6	13.7	19.7	3.7	3.2	4.2	3.1	2.3	3.3	3.4	3.5	4.2	4.4	3.1	4.0	3.9	4.4	4.3	4.1	3.6	3.5	3.4	3.3	3.6	3.9
Alcohol drinker status: Never	2.6	3.1	6.8	-1.9	-1.5	-1.8	-1.6	-1.3	-1.7	-1.7	-2.6	-0.5	-1.9	-2.4	-2.2	-1.6	-0.8	-1.3	-1.7	-1.8	-1.8	-1.7	-2.5	-1.6	-1.7
Chest pain or discomfort	2.5	3.7	8.8	-1.8	-1.7	-1.8	-2.2	-1.0	-1.8	-1.9	-1.4	-1.8	-2.4	-2.5	-1.8	-1.8	-2.1	-1.7	-1.9	-2.2	-1.7	-1.9	-3.0	-1.4	-1.7
Leg pain on walking	2.5	3.1	4.9	1.9	1.3	1.8	1.7	1.9	1.9	1.4	0.6	1.5	2.1	2.2	1.8	1.6	1.9	1.6	1.9	2.1	1.9	1.6	1.8	1.7	1.8
Leg fat-free mass (left)	2.4	12.5	17.8	3.5	3.0	4.1	2.8	2.1	3.0	3.2	3.5	4.0	4.2	3.0	3.9	3.9	4.2	4.2	3.9	3.3	3.3	3.2	3.2	3.4	3.8
Neuroticism score	2.4	5.0	9.6	1.9	2.3	2.2	2.6	1.8	2.1	1.3	2.0	1.5	2.8	2.8	3.1	2.4	1.6	3.1	2.4	2.5	1.8	2.0	1.9	1.8	2.3
Mother’s age at death	2.4	3.0	5.0	1.6	1.5	2.2	1.4	1.4	1.7	1.3	2.2	1.3	1.9	1.0	2.0	1.9	1.0	2.0	2.0	2.2	1.7	1.8	0.3	2.0	2.1
Tinnitus: Yes, now most or all of the time	2.4	2.8	5.7	-2.3	-2.3	-1.7	-1.6	-1.7	-2.3	-2.0	0.1	-1.0	-1.5	-1.3	-1.1	-0.9	-1.2	-0.3	-1.6	-2.0	-2.3	-1.9	-0.6	-2.4	-1.9
Neuroticism (2016)	2.3	3.2	7.8	1.3	1.6	2.0	1.6	1.7	1.5	0.9	2.0	1.9	1.9	1.7	2.6	2.6	1.7	2.8	2.0	1.9	1.3	1.4	1.1	1.2	1.7
Leg predicted mass (left)	2.3	12.2	17.5	3.5	3.0	4.1	2.8	2.1	3.0	3.2	3.4	4.0	4.2	3.0	3.9	3.8	4.2	4.1	3.9	3.3	3.3	3.2	3.1	3.4	3.7
Medication: Gliclazide	2.3	2.5	6.1	-1.8	-1.4	-1.4	-1.4	-1.5	-1.9	-1.9	-0.7	-0.6	-1.5	-2.5	-1.5	-1.2	-1.4	-0.6	-1.4	-2.0	-1.9	-1.1	-2.3	-1.9	-1.5
Qualifications: CSEs or equivalent	2.1	2.8	5.0	-1.9	-1.5	-1.5	-1.9	-1.2	-1.8	-1.6	0.0	-0.9	-1.8	-2.1	-1.8	-1.5	-1.4	-1.0	-1.5	-2.0	-1.9	-1.7	-1.7	-2.2	-2.1
Noisy workplace	2.1	2.6	5.6	1.4	1.4	1.4	1.7	1.6	1.8	2.1	1.2	1.3	2.0	1.8	1.2	0.9	1.6	1.0	1.4	2.0	1.6	1.5	2.4	1.5	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	2.1	3.2	7.0	1.4	1.9	1.8	1.7	1.5	0.8	-0.0	2.4	2.4	2.1	1.1	1.9	2.2	2.1	2.6	2.1	1.6	1.1	1.7	0.7	1.9	2.2
Fractured/broken bones in last 5 years	2.1	2.7	7.0	-1.5	-0.8	-2.1	-1.5	-1.2	-1.3	-1.3	-1.8	-0.5	-1.8	-2.6	-2.2	-1.8	-0.8	-1.8	-1.8	-2.1	-1.4	-1.2	-2.2	-1.5	-1.6
Ulcerative Colitis (UC)	2.0	3.7	9.9	-1.9	-3.1	-2.2	-2.4	-2.2	-1.9	-1.2	-2.0	-1.3	-1.7	-1.5	-1.9	-1.7	-1.4	-1.7	-2.0	-2.0	-1.8	-2.1	-1.7	-1.7	-1.9
Average weekly spirits intake	2.0	2.5	5.5	1.4	1.2	1.7	1.8	0.7	1.7	2.0	0.1	1.3	2.1	1.8	1.6	1.1	1.9	1.4	1.4	2.1	1.6	1.3	2.4	1.1	1.2
Hand grip strength (right)	2.0	5.3	9.9	2.2	1.8	2.7	2.1	1.4	2.2	2.3	3.1	2.0	2.8	1.8	2.5	2.1	1.9	2.4	2.5	2.5	2.3	2.5	1.8	2.5	2.6
Fed-up feelings	2.0	3.7	5.9	1.9	2.1	1.8	1.8	2.3	2.1	1.2	0.9	1.2	2.2	2.4	2.4	1.6	1.5	2.1	2.1	2.4	1.9	1.6	1.5	1.7	1.9
Wheeze or whistling in the chest in last year	2.0	3.6	6.9	1.7	2.0	2.0	2.6	2.2	2.1	1.6	1.1	2.2	2.2	1.2	2.0	1.7	1.8	2.3	2.1	1.7	1.8	1.9	0.3	1.7	2.0
Alzheimer’s Disease (in father)	1.9	2.0	4.2	1.4	1.9	1.2	1.7	1.5	1.2	1.1	1.1	2.1	1.6	0.9	0.9	1.4	1.7	1.1	1.5	1.4	1.4	1.9	0.6	1.1	1.4
Comparative height size at age 10	1.9	10.5	22.8	3.0	2.8	3.8	2.4	0.8	2.5	3.5	4.8	3.2	4.1	2.8	3.2	2.9	3.5	3.6	3.3	3.3	2.9	3.0	4.2	2.8	3.2
Osteoporosis (self-reported)	1.9	2.4	9.7	1.1	1.3	1.3	1.4	0.8	1.1	1.0	0.4	2.7	2.0	1.1	1.0	1.5	3.1	1.7	1.4	1.5	1.0	1.2	2.1	1.0	1.4
Medication: Paracetamol	1.9	2.9	4.7	2.0	2.2	2.0	1.6	1.5	1.9	1.7	1.9	1.3	1.9	1.3	1.4	1.0	1.4	1.1	1.7	2.0	1.9	1.7	1.5	1.9	1.7
Intelligence (Savage-Jansen 2018)	1.8	5.4	8.0	-2.3	-2.2	-2.6	-2.5	-1.3	-2.6	-2.0	-1.4	-2.5	-2.8	-2.1	-2.5	-2.1	-2.7	-2.5	-2.7	-2.4	-2.3	-2.2	-2.1	-2.2	-2.3
Verbal and Numeric Reasoning (VNR)	1.8	4.3	7.1	-2.3	-1.8	-2.0	-2.4	-1.4	-2.7	-2.5	-1.3	-2.5	-2.3	-1.4	-1.7	-1.9	-2.6	-1.6	-2.1	-2.1	-2.2	-2.1	-1.7	-2.2	-2.2
Alcohol intake versus 10 years previously	1.8	2.7	5.6	-2.1	-1.2	-1.6	-1.3	-1.3	-2.4	-1.9	0.5	-0.5	-1.7	-2.4	-2.1	-1.2	-1.0	-1.3	-1.7	-2.1	-2.1	-1.2	-1.4	-1.9	-1.6
Mouth/teeth dental problems: Loose teeth	1.8	2.1	4.5	-1.8	-1.7	-1.6	-0.8	-0.8	-1.7	-2.1	-0.9	-0.9	-1.6	-1.6	-1.8	-1.1	-1.3	-1.3	-1.6	-1.6	-1.9	-1.1	-1.4	-1.3	-1.2
Commuting to job workplace: Walk	1.8	2.0	4.0	-1.6	-1.0	-1.4	-1.2	-1.9	-1.3	-1.8	-0.5	-0.4	-1.6	-1.1	-1.1	-0.9	-0.3	-0.7	-1.4	-1.9	-1.6	-1.7	-1.8	-2.0	-1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.7	2.2	4.7	1.1	1.4	1.4	1.5	1.0	0.7	0.2	2.0	2.1	1.8	1.1	1.3	1.6	2.2	2.0	1.6	1.5	0.8	1.4	1.3	1.3	1.6
Loneliness, isolation	1.7	2.3	4.0	1.5	2.0	1.7	1.7	0.8	1.3	1.1	0.8	1.9	1.9	1.1	1.4	1.5	1.9	1.8	1.7	1.4	1.4	1.6	1.0	1.3	1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.5	8.5	-2.3	-1.4	-2.0	-1.7	-2.9	-2.3	-1.9	-0.0	-0.9	-1.8	-1.9	-1.9	-1.3	-1.1	-1.3	-2.2	-2.2	-2.4	-1.9	-1.2	-2.2	-2.0
Number of operations (self-reported)	1.7	2.6	9.0	0.9	0.7	2.1	0.8	1.3	0.6	-0.0	1.1	2.2	2.0	1.2	2.0	2.4	1.7	3.0	2.0	1.5	1.0	1.4	0.8	1.3	1.8
Hayfever/allergic rhinitis (self-reported)	1.6	2.2	5.4	1.4	1.1	1.9	1.8	2.3	1.3	0.7	-0.8	1.1	1.5	1.4	1.8	1.6	1.0	2.0	1.8	1.5	1.3	1.5	0.3	1.3	1.5
Hair/balding pattern: Pattern 3	1.6	2.5	9.4	-0.9	-1.3	-1.6	-1.2	-0.2	-0.6	-1.1	-3.1	-2.3	-2.2	-0.7	-1.2	-1.5	-1.8	-2.1	-1.5	-1.2	-0.9	-1.9	-1.8	-1.0	-1.6
Loud music exposure frequency	1.6	1.7	3.6	1.4	1.9	0.9	1.9	1.4	1.7	1.6	1.0	0.6	1.3	1.2	1.0	0.8	0.6	0.6	1.1	1.3	1.5	1.4	0.3	1.7	1.6
Medication: Paracetamol	1.6	2.7	5.0	2.0	2.2	1.8	1.8	1.5	1.9	1.5	1.8	0.8	1.7	1.6	1.4	0.9	0.9	1.0	1.7	2.1	1.9	1.7	1.3	1.7	1.6
Knee pain experienced in last month	1.6	2.4	3.6	1.6	1.7	1.5	1.6	1.0	1.7	1.7	1.9	1.6	1.9	1.2	1.7	1.3	1.9	1.5	1.5	1.4	1.6	1.5	1.4	1.3	1.5
Whole body water mass	1.6	8.9	12.7	3.0	2.4	3.5	2.2	1.7	2.6	3.0	3.2	3.3	3.6	2.6	3.3	3.1	3.5	3.4	3.2	2.8	2.8	2.6	2.8	3.1	3.2
Impedance of whole body	1.6	8.0	11.4	-3.1	-2.3	-3.1	-2.6	-2.2	-2.9	-2.5	-1.5	-2.7	-3.3	-2.6	-3.4	-3.0	-3.0	-3.0	-3.2	-2.9	-3.0	-2.8	-1.9	-3.2	-3.3
Primary Biliary Cirrhosis	1.5	2.2	3.6	1.4	1.8	1.4	1.7	1.1	1.5	1.6	1.3	1.8	1.9	0.9	1.0	1.0	1.9	1.1	1.4	1.5	1.5	1.7	1.6	1.4	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.5	2.0	4.2	1.5	1.0	1.6	1.2	2.0	1.5	0.7	0.3	1.1	1.5	1.6	1.7	1.3	1.3	1.4	1.6	1.7	1.5	1.2	0.7	1.8	1.6
Sitting height	1.5	10.3	20.7	-3.4	-4.2	-2.9	-4.5	-3.2	-3.9	-2.7	-1.3	-1.9	-3.6	-3.5	-2.9	-2.1	-2.1	-2.1	-3.4	-3.8	-3.6	-3.9	-2.4	-3.3	-3.5
Arm fat percentage (right)	1.5	6.0	10.6	2.4	2.1	2.8	2.4	2.1	2.3	1.7	0.6	2.9	2.9	2.1	2.9	2.8	2.9	3.2	3.0	2.5	2.3	2.4	1.6	2.1	2.5
Depression (self-reported)	1.5	1.8	3.7	1.1	1.0	1.2	1.1	1.1	0.8	0.4	1.6	1.9	1.7	0.9	1.4	1.4	1.9	1.7	1.5	1.4	1.0	1.4	0.6	1.4	1.6
Ever highly irritable/argumentative for 2 days	1.5	1.7	4.0	1.1	1.3	1.1	1.4	1.2	1.1	0.8	0.3	1.7	1.6	1.5	1.2	1.4	2.0	1.3	1.1	1.2	1.2	1.3	1.3	1.4	1.5
Medication: Omeprazole	1.5	1.8	5.6	-1.1	-1.0	-1.0	-1.3	-0.7	-1.3	-1.6	-1.1	-0.8	-1.5	-1.9	-1.3	-1.1	-1.2	-1.0	-1.3	-1.2	-1.3	-1.4	-2.4	-1.4	-1.4
Overall health rating	1.5	3.1	6.6	-2.2	-1.2	-1.8	-1.3	-1.2	-2.3	-2.6	-1.2	-0.4	-1.6	-2.6	-1.9	-1.3	-1.2	-0.6	-1.6	-2.1	-2.2	-1.2	-2.4	-2.1	-1.6
Had major operations	1.5	1.8	4.2	1.1	0.6	1.2	1.2	1.2	0.9	0.5	0.8	1.7	1.5	1.3	1.6	2.0	1.2	1.8	1.6	1.3	1.1	1.5	0.7	1.3	1.6
Whole body fat-free mass	1.5	8.5	12.0	3.0	2.4	3.4	2.1	1.6	2.5	2.9	3.2	3.2	3.5	2.5	3.2	3.0	3.3	3.3	3.1	2.7	2.8	2.6	2.8	3.0	3.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.7	3.7	1.5	1.4	1.7	1.3	1.5	1.0	0.5	0.8	1.3	1.4	0.9	0.9	1.3	1.0	1.2	1.6	1.2	1.4	1.9	0.9	1.5	1.6
Cholesterol lowering medication	1.5	2.3	7.2	-1.1	-1.6	-1.7	-1.1	-0.6	-1.0	-0.9	-2.7	-1.1	-1.7	-1.5	-1.6	-1.6	-1.1	-1.6	-1.5	-1.5	-1.2	-1.5	-2.0	-1.5	-1.7
Depression (Nagel 2018)	1.4	2.2	4.5	1.4	1.2	1.7	1.5	2.0	1.7	1.3	0.3	0.8	1.5	1.5	2.1	1.5	1.0	1.7	1.6	1.8	1.5	1.1	0.1	1.6	1.6
Medication: Seretide 50 evohaler	1.4	1.7	5.0	0.6	0.8	1.4	1.0	0.8	1.1	1.3	1.2	2.2	1.8	0.7	1.4	1.4	2.1	2.1	1.3	0.7	0.7	0.8	1.2	0.5	1.0
Smoking status: Previous	1.4	2.1	3.4	1.3	1.4	1.5	1.5	1.9	1.3	1.1	1.2	1.3	1.6	1.2	1.6	1.5	1.3	1.3	1.6	1.2	1.5	1.7	1.0	1.6	1.7
Arm fat percentage (left)	1.4	5.6	9.0	2.4	2.1	2.7	2.4	2.0	2.3	1.8	0.5	2.7	2.8	2.0	2.7	2.6	2.8	3.0	2.8	2.5	2.3	2.3	1.5	2.1	2.4
Basal metabolic rate	1.4	7.7	11.0	2.8	2.2	3.3	2.0	1.6	2.4	2.7	2.9	3.1	3.3	2.4	3.1	2.9	3.3	3.3	3.0	2.6	2.6	2.4	2.7	2.8	3.0
Blood Red Count	1.3	12.8	18.8	-4.1	-4.3	-3.5	-3.5	-3.7	-3.7	-3.2	-3.2	-2.7	-3.6	-3.2	-3.1	-2.8	-2.7	-2.8	-4.0	-3.7	-4.1	-4.3	-3.0	-4.2	-4.3
Hair Pigment	1.3	36.0	45.2	6.6	5.1	6.5	6.3	6.2	6.6	6.2	5.2	5.0	6.3	5.8	5.6	5.3	5.2	5.0	6.4	6.7	6.5	6.4	6.0	6.2	6.2
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	2.5	1.4	1.3	1.2	1.4	1.0	1.3	1.4	0.2	1.0	1.6	1.3	1.4	0.9	0.9	1.2	1.2	1.0	1.3	1.4	1.3	1.3	1.4
Prospective memory result	1.3	1.6	4.0	1.4	0.8	1.4	1.3	1.3	1.5	1.1	-0.1	1.2	1.5	1.8	1.2	0.8	1.6	0.9	1.1	1.2	1.3	1.0	2.0	1.2	1.1
Worry too long after embarrassment	1.3	2.2	4.0	1.7	2.0	1.3	2.0	1.0	1.9	2.0	1.6	0.9	1.7	1.7	1.6	0.8	1.2	1.1	1.3	1.4	1.6	1.4	1.2	1.1	1.2
Emphysema/chronic bronchitis	1.3	1.4	2.6	1.4	1.3	1.1	1.1	0.9	1.6	1.3	-0.4	1.3	1.4	0.7	1.2	0.8	1.4	0.9	1.3	1.3	1.6	1.2	0.3	1.3	1.3
Hearing aid user	1.3	1.5	4.5	1.4	0.8	1.1	1.3	0.3	1.4	1.6	1.1	0.7	1.4	1.6	0.8	0.6	1.1	0.4	1.0	1.7	1.4	1.0	2.1	1.4	1.1
Vitamin and mineral supplements	1.2	1.7	5.4	0.5	0.3	1.3	1.1	0.5	0.7	1.2	1.7	1.4	1.8	1.4	1.6	1.6	1.4	2.0	1.1	1.0	0.7	0.9	2.3	0.6	1.0
Medication: Metformin	1.2	1.6	4.3	-1.5	-1.5	-1.1	-1.3	-1.1	-1.4	-1.4	-0.6	-0.2	-1.0	-2.1	-0.9	-0.7	-0.8	-0.1	-1.1	-1.5	-1.6	-1.0	-1.6	-1.9	-1.4
Financial difficulties in last 2 years	1.2	1.7	4.1	1.0	1.2	1.4	0.9	1.5	1.0	0.8	1.2	2.0	1.5	0.6	1.0	1.1	2.0	1.4	1.4	1.2	1.1	1.2	1.0	1.3	1.4
Fluid intelligence score	1.2	2.4	5.8	-2.0	-1.7	-1.4	-1.8	-1.3	-2.3	-2.4	-0.6	-1.6	-1.6	-0.7	-0.7	-0.6	-1.8	-0.4	-1.4	-1.4	-2.0	-1.6	-1.2	-1.8	-1.5
Trunk fat-free mass	1.2	7.1	9.9	2.8	2.2	3.1	1.9	1.5	2.3	2.9	3.1	2.7	3.1	2.4	2.9	2.7	2.9	2.9	2.8	2.4	2.6	2.4	2.7	2.8	2.9
Happiness	1.2	1.4	4.0	1.0	0.9	1.0	0.9	1.2	0.6	0.3	2.0	1.3	1.5	1.1	0.9	1.2	1.3	1.4	1.2	1.2	0.9	1.3	1.5	1.1	1.4
Trunk predicted mass	1.2	6.9	9.8	2.7	2.2	3.1	1.8	1.4	2.3	2.8	3.1	2.7	3.1	2.4	2.9	2.6	2.8	2.8	2.8	2.4	2.5	2.3	2.7	2.8	2.9
Tense / ‘highly strung’	1.2	1.9	8.5	0.6	1.3	1.7	1.5	0.7	0.7	0.1	1.6	1.4	1.7	1.3	2.1	2.1	1.0	2.9	1.5	1.1	0.5	1.0	0.6	0.7	1.4
Medication: Ibuprofen	1.2	1.5	3.5	1.4	1.3	1.3	1.2	1.9	1.1	1.3	1.1	1.2	1.4	0.7	1.0	0.9	1.2	1.1	1.3	1.5	1.3	1.3	0.8	1.1	1.2
Diabetes diagnosed by doctor	1.2	2.0	4.3	-1.8	-1.1	-1.4	-1.2	-1.1	-1.9	-1.8	0.3	-0.5	-1.1	-2.0	-1.2	-0.8	-1.5	-0.0	-1.2	-1.8	-1.8	-0.8	-1.8	-2.1	-1.4
Arm fat mass (left)	1.2	4.8	8.6	2.2	1.7	2.5	1.9	1.5	2.0	1.7	0.8	2.6	2.6	1.9	2.6	2.5	2.7	2.9	2.6	2.2	2.1	1.9	1.6	1.9	2.2
Height	1.1	21.2	44.9	4.2	4.0	5.3	3.7	1.9	3.7	5.3	6.7	5.0	5.5	3.9	4.5	4.6	4.9	4.9	4.6	3.9	4.1	4.4	5.9	3.7	4.3
Ever used hormone-replacement therapy (HRT)	1.1	1.3	2.5	-1.2	-1.1	-1.2	-1.0	-1.1	-1.4	-1.3	-1.4	-0.6	-1.1	-1.4	-1.0	-0.9	-0.9	-0.6	-1.2	-1.4	-1.4	-1.0	-0.8	-1.6	-1.3
Hearing difficulty/problems with background noise	1.1	1.7	3.2	1.1	1.7	1.4	1.8	0.7	1.2	1.2	1.7	1.1	1.6	1.3	1.5	1.2	0.8	1.5	1.4	1.2	1.1	1.5	1.0	0.8	1.2
Had other major operations	1.1	1.4	3.1	1.0	1.1	1.3	1.2	1.5	1.0	1.1	0.5	1.8	1.6	0.4	1.2	1.3	1.4	1.4	1.2	0.9	1.1	1.5	0.6	0.8	1.2
Mouth/teeth dental problems: Dentures	1.1	1.9	3.9	-1.3	-0.9	-1.8	-0.7	-1.0	-0.7	-0.6	-1.4	-0.7	-1.2	-1.8	-1.8	-2.0	-0.9	-1.8	-1.7	-1.6	-1.2	-1.0	-1.4	-1.6	-1.6
Pain type(s) experienced in last month: Hip pain	1.1	1.3	2.5	1.5	1.1	1.0	1.4	1.6	1.6	1.4	0.1	0.9	1.1	0.9	1.2	1.0	1.3	0.8	1.2	1.2	1.4	1.0	0.4	1.0	1.0
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	3.6	0.5	1.2	1.5	1.3	1.1	0.6	0.3	-0.2	1.2	1.4	0.9	1.4	1.5	0.9	1.9	1.3	0.8	0.5	1.5	0.9	0.6	1.2
Forced expiratory volume in 1-second (FEV1)	1.0	3.5	6.8	-1.9	-1.5	-1.7	-2.3	-2.6	-2.0	-1.2	1.4	-1.8	-2.0	-2.1	-1.9	-1.9	-1.8	-1.6	-2.0	-1.7	-1.9	-2.2	-1.8	-1.6	-1.9
Arm fat mass (right)	1.0	4.2	8.3	2.1	1.6	2.4	1.8	1.5	1.8	1.5	0.8	2.4	2.5	1.8	2.5	2.4	2.4	2.9	2.5	2.1	1.9	1.9	1.4	1.8	2.1
Qualifications: O levels/GCSEs or equivalent	1.0	1.5	3.5	-1.8	-1.4	-1.3	-1.5	-1.2	-1.6	-1.5	0.1	-1.1	-1.3	-0.4	-0.4	-0.2	-1.0	0.1	-1.1	-1.2	-1.8	-1.9	-0.8	-1.6	-1.3
Neck or shoulder pain in last month	1.0	1.4	3.9	2.0	1.6	1.1	1.2	1.3	1.6	1.3	0.5	-0.0	0.8	1.0	1.1	0.4	-0.1	0.3	1.2	1.0	1.7	1.2	-0.5	1.8	1.4
Guilty feelings	1.0	1.4	2.9	1.0	1.6	1.1	1.6	1.2	1.0	0.4	1.0	1.1	1.7	1.2	1.2	0.9	0.6	1.6	1.3	1.3	0.9	1.6	1.0	0.8	1.2
Commuting to job workplace: Cycle	1.0	1.2	2.1	-1.2	-0.6	-1.2	-1.4	-0.8	-1.4	-1.2	0.2	-1.2	-1.4	-0.8	-1.3	-1.0	-1.0	-1.2	-1.1	-1.1	-1.2	-1.0	-0.7	-1.3	-1.3
Myopia	1.0	1.5	6.0	-0.8	-0.6	-1.5	-0.9	-1.2	-0.6	-0.5	-1.1	-1.4	-1.5	-0.5	-1.6	-1.6	-1.0	-2.4	-1.7	-1.1	-0.7	-1.2	-0.4	-0.9	-1.4
Type 2 Diabetes (T2D) (2018)	0.9	1.7	3.9	-1.8	-1.6	-1.2	-1.4	-1.1	-1.9	-1.7	-0.3	-0.1	-1.0	-1.8	-0.9	-0.4	-0.8	0.0	-1.0	-1.4	-1.8	-1.0	-1.4	-2.0	-1.4
Diabetes (self-reported)	0.9	1.4	3.3	-1.5	-1.0	-1.3	-0.9	-1.1	-1.6	-1.6	-0.3	-0.1	-0.8	-1.7	-1.1	-0.7	-0.9	0.0	-1.0	-1.4	-1.6	-0.7	-1.4	-1.8	-1.2
Weight	0.9	4.2	7.3	2.1	1.6	2.5	1.6	1.2	1.7	1.7	1.4	2.7	2.5	1.7	2.2	2.3	2.7	2.6	2.4	1.9	1.9	1.8	1.8	1.9	2.1
Age at last live birth	0.9	1.3	3.4	1.0	0.5	1.4	0.5	1.4	0.7	0.7	1.8	0.5	1.0	1.1	1.4	1.2	0.7	1.3	1.4	1.4	1.1	0.8	0.7	1.6	1.3
Commuting to job workplace: Public transport	0.9	1.0	4.0	-1.0	-1.7	-0.8	-1.2	-1.0	-1.1	-1.2	-0.6	-0.3	-1.0	-1.7	-0.6	-0.5	-0.4	-0.4	-0.7	-0.8	-0.8	-0.9	-2.0	-0.7	-0.7
Trunk fat mass	0.8	3.3	6.2	1.8	1.4	2.1	1.5	1.0	1.6	1.5	0.7	2.4	2.3	1.5	2.0	2.1	2.5	2.5	2.1	1.8	1.6	1.5	1.6	1.5	1.8
Mouth/teeth dental problems: Mouth ulcers	0.8	1.2	3.9	0.4	-0.1	1.6	1.3	1.0	0.3	0.1	1.1	1.5	1.3	0.7	1.4	1.4	1.1	2.0	1.3	0.7	0.4	1.2	0.5	0.9	1.3
Breast cancer (self-reported)	0.8	0.9	1.8	0.9	0.5	1.2	0.5	1.0	0.6	0.5	0.6	0.9	1.1	1.1	1.0	1.2	1.1	1.4	1.2	0.8	0.8	1.1	1.0	0.8	1.1
Worry (Nagel 2018)	0.7	1.5	5.5	0.8	0.9	1.4	1.0	1.0	0.8	0.0	0.6	-0.1	1.3	2.1	2.3	1.8	-0.1	2.4	1.4	1.4	0.6	0.7	0.7	0.7	1.1
Alzheimer’s Disease (including proxy)	0.7	1.1	3.4	1.0	1.5	0.6	1.3	1.3	1.0	1.4	1.8	1.4	1.1	-0.1	0.3	0.4	1.3	0.0	0.7	0.8	1.0	1.3	-0.1	0.7	0.8
Waist Hip Ratio (WHR)	0.7	3.0	7.2	0.8	2.0	1.5	1.6	1.5	1.1	1.0	0.7	2.1	2.0	2.0	2.2	2.5	2.3	2.7	1.5	1.3	0.7	1.1	2.7	0.5	1.2
Stomach or abdominal pain in last month	0.7	0.9	6.0	-0.5	0.5	-0.9	0.0	0.4	-0.5	-1.2	-1.4	-0.1	-0.6	-1.8	-0.9	-1.0	-0.8	-0.6	-0.6	-0.8	-0.6	-0.2	-2.5	-0.2	-0.4
Supplements: Glucosamine	0.7	1.0	4.5	-0.6	-0.5	-0.7	-0.7	-0.7	-0.6	-0.8	0.0	-1.5	-1.3	-1.2	-0.6	-1.1	-1.5	-0.9	-0.7	-0.7	-0.5	-0.9	-2.1	-0.7	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.0	3.2	0.5	0.9	1.4	1.1	0.1	0.7	0.1	1.6	1.3	1.2	0.5	1.5	1.3	1.0	1.8	1.1	0.7	0.5	0.7	-0.1	0.9	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	2.8	1.2	1.2	0.9	1.2	1.7	1.0	1.3	0.9	0.5	1.0	0.8	0.6	0.4	0.5	0.3	0.8	1.2	1.1	1.1	0.7	0.9	0.8
Length of working week for main job	0.7	0.7	1.8	-0.9	-0.7	-1.0	-0.7	-0.6	-0.7	-0.2	-0.8	-0.3	-0.8	-1.3	-0.9	-1.0	-0.5	-0.8	-1.0	-1.4	-0.7	-0.9	-0.6	-1.1	-1.0
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.4	1.3	1.1	0.6	1.2	1.5	1.1	1.3	0.1	0.7	0.9	0.9	0.5	0.4	0.8	0.2	0.8	0.7	1.2	1.1	1.3	0.9	0.9
Medication: Ventolin 100micrograms inhaler	0.7	0.9	3.5	0.6	0.4	1.3	0.7	0.9	0.9	0.6	0.3	1.9	1.1	0.1	0.8	0.8	1.7	1.6	1.2	0.6	0.7	0.6	-0.1	0.4	0.7
Shortness of breath walking on level ground	0.7	0.8	1.8	-0.8	-0.7	-1.1	-1.0	-0.9	-0.8	-0.6	-0.6	-1.3	-1.1	-0.1	-0.8	-0.9	-0.9	-1.1	-1.2	-0.8	-0.9	-1.3	-0.1	-0.7	-0.9
Medication for pain relief, constipation, heartburn	0.7	1.2	3.6	0.6	0.6	1.0	1.1	-0.3	0.7	1.2	1.8	1.0	1.2	1.3	1.0	1.1	1.2	1.0	0.9	0.7	0.7	1.1	1.9	0.9	1.1
Pulse rate, automated reading	0.7	2.3	5.2	1.4	0.5	1.6	1.6	1.0	1.3	1.0	0.2	1.2	1.9	2.0	2.1	1.6	1.3	2.3	1.8	1.4	1.3	1.4	1.9	1.3	1.6
Average weekly champagne plus white wine intake	0.7	1.0	1.8	1.3	1.4	1.0	0.5	1.1	0.9	0.6	0.9	1.1	0.8	0.6	0.6	1.1	1.2	0.7	1.3	1.2	1.2	1.1	0.7	1.2	1.1
Type 2 Diabetes (T2D) (2012)	0.6	0.7	3.1	-1.6	-1.3	-1.8	-1.1	-1.2	-1.7	-1.6	-0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
BMI	0.6	3.2	6.6	1.9	1.1	2.2	1.5	1.3	1.7	1.1	0.6	1.9	1.9	1.9	2.4	2.2	2.0	2.6	2.2	2.1	1.7	1.4	1.0	1.7	1.8
Diabetes (mother)	0.6	0.8	2.2	-1.1	-0.2	-1.1	-0.4	-0.5	-1.0	-0.9	-1.1	-0.1	-0.9	-1.4	-0.9	-0.5	-0.5	-0.4	-0.9	-0.9	-1.2	-0.8	-1.5	-1.1	-0.9
Relative age voice broke	0.6	0.9	2.5	0.5	0.8	1.0	1.0	0.6	0.8	0.4	0.4	1.5	1.1	1.0	0.7	1.2	1.6	1.0	0.8	0.7	0.7	1.0	1.1	0.5	0.9
Waist circumference	0.6	2.1	5.4	1.3	1.3	1.7	1.4	0.6	1.1	0.7	0.4	1.9	1.8	1.3	1.7	1.8	1.8	2.3	1.7	1.3	1.0	1.2	1.4	0.9	1.3
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	2.7	0.3	0.8	0.4	0.5	0.2	-0.0	-0.4	1.1	0.9	1.2	1.1	1.1	1.1	0.7	1.6	0.7	0.4	0.1	0.8	1.4	0.3	0.8
Mouth/teeth dental problems	0.6	1.0	2.7	0.7	0.6	1.0	0.2	-0.2	0.6	0.8	1.0	0.4	1.1	1.4	1.6	1.7	0.8	1.6	1.0	1.3	0.7	0.2	1.1	0.7	0.8
Pulse wave reflection index	0.6	0.8	1.5	-1.1	-0.3	-0.9	-0.5	-0.4	-0.6	-0.4	0.1	-0.8	-1.1	-0.9	-1.2	-1.0	-0.9	-1.2	-1.1	-1.1	-0.8	-0.9	-0.4	-1.1	-1.1
Whole body fat mass	0.6	2.3	4.7	1.6	1.1	1.8	1.2	0.8	1.3	1.2	0.3	2.1	1.9	1.2	1.8	1.8	2.2	2.2	1.8	1.5	1.4	1.2	1.1	1.3	1.5
Commuting to job workplace: Car/motor vehicle	0.6	0.6	2.3	0.6	0.3	0.8	0.7	0.7	0.6	0.6	-0.2	1.1	1.1	0.7	0.7	0.8	1.1	1.0	0.8	0.7	0.6	0.7	1.5	0.7	0.8
Illnesses of siblings: Diabetes	0.6	0.7	3.0	-0.0	1.1	0.9	0.9	-0.2	0.2	0.3	1.7	1.0	1.2	-0.2	1.2	1.0	0.5	1.7	0.6	0.8	0.0	0.9	-0.3	0.0	0.7
Ever had bowel cancer screening	0.6	0.7	3.1	0.2	0.6	1.2	1.1	0.4	0.4	0.4	-0.2	0.6	1.1	0.7	1.5	1.1	0.3	1.8	0.8	0.5	0.3	0.8	0.6	0.1	0.7
Supplements: Calcium	0.6	0.6	2.0	-0.9	-1.0	-0.4	-0.9	-1.2	-1.4	-1.2	0.2	-0.3	-0.8	-1.0	-0.8	-0.4	-0.5	-0.3	-0.5	-0.7	-0.9	-0.5	-1.0	-0.4	-0.4
HbA1C	0.5	0.5	1.5	-1.2	-0.7	-0.7	-0.8	-0.7	-1.2	-0.7	0.5	0.1	-0.4	-0.5	-0.1	0.1	0.2	0.2	-0.7	-0.8	-1.1	-0.8	0.2	-1.2	-0.8
Hearing difficulty/problems: Yes	0.5	0.8	2.1	0.6	0.7	0.9	1.0	0.1	0.6	1.1	0.9	1.4	1.4	0.6	0.7	0.6	1.1	1.3	0.9	0.5	0.7	1.1	1.2	0.3	0.7
Diabetes (father)	0.5	0.6	3.5	0.2	0.6	1.1	0.4	-0.1	0.2	-0.3	0.9	1.2	0.9	-0.2	1.3	1.2	0.7	1.9	0.9	0.5	0.1	0.5	-0.7	-0.2	0.4
Forced vital capacity (FVC)	0.5	1.9	4.5	-1.2	-1.2	-1.1	-1.9	-2.1	-1.5	-0.7	1.5	-1.2	-1.3	-1.6	-1.2	-1.4	-1.3	-1.0	-1.4	-1.3	-1.3	-1.5	-1.3	-1.0	-1.3
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	3.4	0.5	1.0	0.6	0.9	0.4	0.4	-0.0	1.2	1.8	1.1	0.1	0.4	0.9	1.6	1.4	0.9	0.4	0.4	0.8	0.6	0.3	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	3.3	-0.8	-1.3	-1.1	-1.8	-1.5	-1.1	-0.4	1.0	-1.3	-1.5	-1.6	-1.1	-1.3	-1.2	-1.3	-1.2	-1.1	-0.9	-1.6	-1.7	-0.6	-1.2
Arm predicted mass (right)	0.5	2.6	4.2	1.6	1.0	2.0	0.7	0.5	1.2	1.7	1.8	1.9	1.9	1.3	1.8	1.7	2.1	2.0	1.7	1.4	1.5	1.2	1.7	1.6	1.7
Wears glasses or contact lenses	0.5	0.5	1.0	-0.6	-0.9	-0.5	-1.0	-1.0	-0.8	-0.6	-0.1	-0.3	-0.9	-0.9	-0.7	-0.4	-0.1	-0.6	-0.7	-0.6	-0.7	-0.9	-0.9	-0.8	-0.8
Arm fat-free mass (left)	0.5	2.7	4.8	1.6	1.1	2.0	0.8	0.8	1.2	1.6	1.8	1.9	2.0	1.5	2.0	1.9	2.0	2.2	1.8	1.4	1.4	1.2	1.8	1.7	1.8
Ever had prostate specific antigen (PSA) test	0.5	0.6	0.9	0.9	0.9	0.9	0.7	-0.2	0.6	0.5	0.0	0.6	0.9	0.9	0.8	0.7	0.5	0.7	0.8	0.7	0.8	0.9	0.7	1.0	0.9
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	4.0	-0.8	-0.5	0.3	-0.4	-1.0	-0.7	-1.1	0.1	1.4	0.6	-0.2	0.6	1.0	0.9	2.0	0.3	-0.4	-0.8	-0.3	0.4	-0.9	-0.2
Arm predicted mass (left)	0.5	2.5	5.0	1.5	0.9	2.0	0.8	0.5	1.1	1.5	1.8	1.9	1.9	1.3	2.0	1.8	1.9	2.2	1.7	1.3	1.3	1.1	1.5	1.5	1.7
Schizophrenia vs Biploar Disorder	0.4	0.5	1.1	0.9	0.7	0.6	0.9	1.0	0.9	0.8	0.4	0.3	0.9	1.0	0.8	0.0	0.5	0.4	0.8	0.9	0.9	0.0	0.9	0.8	0.0
Body Mass Index (BMI) (2010)	0.4	0.5	1.5	0.2	0.2	0.9	0.2	0.4	0.4	0.7	0.7	0.8	1.0	0.5	1.0	0.8	1.0	1.2	0.8	0.7	0.5	0.3	0.7	0.6	0.7
Triglycerides	0.4	0.6	2.9	-0.1	-0.3	0.6	0.2	0.8	0.3	0.3	0.4	0.1	0.6	1.6	1.3	1.0	0.5	1.2	0.7	0.6	0.4	0.0	1.7	0.3	0.5
Hypothyroidism (self reported)	0.4	0.8	2.1	0.7	1.2	1.0	0.5	1.5	0.7	0.5	0.9	-0.1	0.7	0.9	1.2	0.9	-0.4	1.0	1.1	1.0	0.9	1.0	0.0	1.1	1.1
Lung FVC	0.4	2.1	4.3	-1.3	-1.7	-1.6	-1.7	-2.1	-1.3	-1.3	-1.7	-1.4	-2.0	-1.0	-0.8	-0.6	-1.3	-1.2	-1.6	-1.1	-1.4	-1.8	-1.4	-1.2	-1.5
Chronotype (morning person)	0.4	0.8	1.8	-1.2	-1.0	-0.9	-1.1	-0.5	-1.1	-0.9	-0.1	-1.4	-0.9	-0.2	-0.9	-0.7	-1.3	-0.7	-1.0	-0.8	-1.0	-0.9	-0.2	-0.9	-0.9
Trunk fat percentage	0.4	1.4	3.3	1.2	0.9	1.4	1.1	0.7	1.1	0.8	-0.2	1.7	1.5	0.9	1.3	1.4	1.8	1.8	1.4	1.2	1.0	0.9	1.0	0.8	1.0
Taking other prescription medications	0.4	0.7	2.6	-0.8	-0.9	-0.3	-1.0	-0.5	-1.0	-1.6	-0.7	-0.2	-0.4	-0.6	0.6	0.4	-0.5	1.3	0.0	-0.6	-0.9	-0.7	-1.6	-0.8	-0.3
Body mass index (BMI)	0.4	1.8	4.0	1.4	1.0	1.5	1.3	1.2	1.2	0.6	-0.3	1.6	1.6	1.1	1.7	1.6	1.6	2.0	1.7	1.3	1.3	1.2	0.4	1.2	1.4
Standing height	0.4	4.4	15.0	1.9	1.6	2.4	0.9	0.3	1.4	2.7	3.9	2.4	2.4	1.6	1.7	1.8	2.7	1.8	1.8	1.6	1.7	1.6	3.2	1.9	1.9
Blood clot in the leg (DVT)	0.4	0.6	3.1	-0.8	-0.6	0.2	-0.4	-1.1	-0.7	-1.1	0.2	1.2	0.5	-0.3	0.5	0.8	0.8	1.8	0.2	-0.4	-0.8	-0.4	0.3	-0.9	-0.3
Arm fat-free mass (right)	0.4	2.0	3.5	1.5	0.9	1.7	0.7	0.5	1.1	1.6	1.5	1.8	1.7	1.0	1.6	1.5	1.9	1.7	1.5	1.1	1.3	1.0	1.4	1.5	1.5
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	3.1	-0.1	-0.4	0.4	-0.3	-0.2	-0.1	-0.5	-0.9	-0.5	0.3	1.3	1.4	1.0	-0.4	1.8	0.7	0.4	-0.2	-0.5	0.6	0.1	0.3
Family relationship satisfaction	0.4	0.5	1.4	-1.0	-1.2	-1.0	-0.6	-1.0	-1.1	-0.8	0.1	0.2	-0.4	-0.6	-0.3	0.2	0.2	0.2	-0.6	-0.9	-1.1	-0.7	0.0	-0.7	-0.4
Osteoarthritis (self-reported)	0.4	0.5	1.4	0.8	0.9	0.7	0.7	-0.4	0.6	0.3	-0.4	0.4	0.7	0.8	1.2	0.9	0.4	1.0	0.9	0.7	0.7	0.6	-0.1	0.7	0.8
Miserableness	0.4	0.6	1.5	0.7	1.1	0.5	1.2	0.7	0.9	0.6	1.1	0.4	0.7	0.9	0.9	0.9	0.5	0.8	0.7	1.0	0.6	0.5	-0.1	0.8	0.9
Financial situation satisfaction	0.4	0.5	1.3	0.1	0.5	0.3	0.5	-0.9	-0.0	-0.1	0.9	1.2	1.0	0.5	0.4	0.6	1.1	1.1	0.6	0.5	0.1	0.6	1.1	0.2	0.6
Alcohol drinker status: Previous	0.4	0.5	1.1	0.3	1.0	0.6	0.5	1.0	0.7	0.8	0.6	0.6	0.8	1.1	0.8	0.8	0.9	0.8	0.6	0.8	0.5	0.4	0.8	0.2	0.5
Alzheimer’s Disease (in mother)	0.3	0.3	4.6	0.3	0.1	0.3	0.3	0.2	0.3	0.7	2.1	0.4	0.4	-0.3	0.2	0.4	0.3	0.4	0.4	0.2	0.4	0.5	-0.3	0.3	0.4
Rheumatoid Arthritis	0.3	0.4	2.0	0.7	1.4	0.2	0.5	-0.1	0.6	1.1	0.7	-0.3	0.5	0.8	0.4	-0.1	-0.0	-0.0	0.4	0.7	0.7	0.5	0.7	0.7	0.5
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	3.2	0.5	-0.6	-0.2	-0.6	0.9	0.3	0.5	-1.8	-0.5	0.0	0.2	0.2	-0.3	-0.1	-0.3	0.1	0.7	0.5	-0.2	0.0	0.7	0.2
Medication for hormone replacement therapy	0.3	0.4	1.6	0.8	0.2	0.7	0.5	1.3	0.3	0.0	0.7	0.9	0.4	0.0	0.1	0.3	0.8	0.3	0.7	0.2	0.6	0.8	0.1	0.7	0.7
Townsend deprivation index at recruitment	0.3	0.4	2.4	0.2	0.5	0.4	0.4	0.1	0.3	0.0	0.1	1.6	0.7	0.1	0.3	0.7	1.4	1.0	0.5	0.1	-0.0	0.3	0.3	0.2	0.5
Average weekly fortified wine intake	0.3	0.3	1.4	0.5	0.8	0.3	0.5	0.0	0.9	1.2	0.3	0.6	0.6	-0.3	0.6	-0.1	1.1	0.0	0.2	0.6	0.7	0.0	-0.1	0.0	-0.0
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.4	-0.3	1.1	-0.8	0.3	-0.5	-0.1	0.3	-0.1	-0.0	-0.5	-0.8	-0.9	-0.9	-0.1	-1.2	-0.6	-0.7	-0.2	-0.3	-0.2	-0.1	-0.4
Multivitamins +/- minerals	0.3	0.3	1.2	-0.3	-0.4	-0.5	-0.5	-0.0	-0.3	-0.8	-1.1	-0.5	-0.8	-0.6	-0.5	-0.6	-0.4	-0.6	-0.4	-0.6	-0.4	-0.5	-1.1	-0.4	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	2.2	0.5	0.4	1.1	0.7	1.5	0.4	0.3	0.5	-0.5	0.3	1.1	1.2	1.1	-0.4	0.7	0.8	0.7	0.6	0.5	0.1	0.8	0.8
Falls in the last year	0.3	0.4	3.9	0.5	0.3	0.4	0.6	0.5	0.3	0.1	-0.1	0.6	0.1	-1.2	-0.1	-0.3	0.0	-0.0	0.3	-0.1	0.5	0.7	-2.0	0.4	0.4
Peak expiratory flow (PEF)	0.3	0.8	1.6	-1.2	-0.1	-0.6	-0.7	-1.3	-1.1	-1.0	1.2	-0.7	-0.7	-0.8	-0.2	-0.4	-0.9	0.3	-0.7	-0.8	-1.3	-1.1	-1.1	-1.0	-0.9
Comparative body size at age 10	0.3	0.7	1.7	1.2	0.8	0.8	1.2	1.0	1.0	0.6	-0.5	-0.1	0.8	1.2	0.8	0.3	-0.2	0.3	0.9	0.8	1.1	1.3	0.2	1.0	1.0
Age at first live birth	0.3	0.6	2.4	-0.3	-0.7	-0.5	-0.9	-0.7	-0.5	-0.5	1.1	-1.5	-0.9	0.2	-0.6	-0.8	-1.1	-1.3	-0.5	-0.0	-0.2	-0.6	0.3	0.3	-0.4
Qualifications: College or University degree	0.3	1.0	1.8	0.8	1.1	1.2	0.7	1.2	0.6	0.8	1.1	1.0	1.0	0.5	0.7	0.8	1.2	0.7	1.1	1.3	0.9	1.1	0.8	1.3	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.1	-0.6	0.0	-0.5	-0.7	0.1	-0.6	-0.5	-0.4	-0.3	-0.6	-0.8	-0.5	-0.4	-0.5	-0.1	-0.4	-0.8	-0.7	-0.3	-0.5	-1.1	-0.7
Suffer from ‘nerves’	0.3	0.5	2.4	-0.6	-0.4	-0.4	-0.5	-0.4	-0.7	-1.1	0.7	-1.3	-0.6	-0.2	0.0	-0.3	-1.6	0.1	-0.5	-0.3	-0.9	-0.6	-1.2	-0.8	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.8	0.1	0.9	-0.8	0.7	0.3	0.2	-0.1	0.3	0.3	-0.3	-0.7	-1.4	-1.1	-0.1	-1.1	-0.3	-0.4	0.1	0.5	-1.0	0.4	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	2.4	-0.7	-0.7	-0.5	-1.1	-1.2	-0.9	-0.3	1.5	0.1	-0.8	-1.4	-0.9	-0.5	0.1	-0.5	-0.7	-0.7	-0.9	-1.1	-0.9	-0.5	-0.7
Average weekly red wine intake	0.3	0.4	1.4	-0.8	-0.7	-0.3	-0.4	-0.1	-1.0	-0.7	-0.9	0.1	-0.4	-1.2	-0.7	-0.6	-0.1	-0.3	-0.6	-0.8	-0.8	-0.5	-0.7	-0.4	-0.5
Unable to work because of sickness or disability	0.3	0.4	2.5	-0.1	0.4	0.5	0.0	-0.5	-0.2	-0.4	0.7	1.1	0.8	-0.6	0.8	0.5	0.7	1.6	0.6	0.4	-0.1	0.4	-0.7	0.2	0.5
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	2.3	-0.3	0.0	-0.1	-0.2	0.1	-0.5	-0.9	-0.2	0.1	-0.4	-1.2	-0.4	-0.2	-0.3	0.0	-0.3	-0.5	-0.5	-0.5	-1.5	-0.7	-0.5
Fasting Glucose	0.2	0.2	2.1	-0.9	0.5	-0.3	-0.1	-0.1	-0.0	0.2	1.4	-0.1	0.0	-0.5	0.3	-0.1	0.1	-0.1	-0.8	-0.1	-0.5	-0.4	-0.4	-0.4	-0.1
HDL Cholesterol	0.2	0.3	1.0	-0.3	-0.3	-1.0	-0.5	-0.8	-0.3	0.0	-0.9	-1.0	-0.8	0.0	-0.5	-0.5	-0.8	-0.9	-0.5	-0.4	-0.2	-0.3	-0.1	-0.4	-0.5
LDL Cholesterol	0.2	0.3	2.4	-0.0	0.0	-0.5	-0.1	-0.1	0.2	0.7	0.2	-0.9	-0.6	-0.0	-0.8	-0.8	-0.5	-1.5	-0.6	-0.2	0.3	-0.3	0.2	0.1	-0.4
Blood Eosinophil Count	0.2	1.7	5.1	1.0	-0.6	1.2	1.2	1.6	1.1	0.1	-1.3	2.3	1.6	0.3	1.3	1.5	1.7	1.8	1.5	1.0	1.0	1.6	-0.1	1.2	1.5
Relative age of first facial hair	0.2	0.4	1.8	0.3	0.3	0.4	0.8	0.4	0.7	0.9	0.3	1.4	0.9	0.1	0.1	0.6	1.3	0.4	0.3	0.5	0.4	0.8	0.6	0.4	0.6
Ever had hysterectomy (womb removed)	0.2	0.3	1.2	-0.3	-0.5	-0.2	-0.3	-0.7	-0.7	-0.8	-0.6	-1.1	-0.6	0.0	-0.0	-0.3	-1.0	-0.2	-0.2	-0.4	-0.4	-0.2	-0.4	-0.2	-0.2
Pain all over the body in last month	0.2	0.2	0.8	-0.5	-0.1	-0.0	-0.1	-0.0	-0.7	-0.9	-0.5	0.4	-0.1	-0.8	-0.5	-0.3	-0.1	0.3	-0.2	-0.5	-0.4	0.0	-0.7	-0.4	-0.1
Time employed in main current job	0.2	0.2	1.1	-0.2	-0.3	-0.5	-0.4	-0.3	-0.0	-0.2	-0.4	-0.2	-0.3	-0.6	-0.8	-0.8	-0.0	-1.0	-0.7	-0.1	-0.2	-0.2	0.2	-0.3	-0.5
Worrier / anxious feelings	0.2	0.5	2.5	-0.1	1.0	0.5	0.6	0.0	0.1	-0.6	0.3	0.9	0.9	0.6	0.9	1.1	0.7	1.6	0.6	0.5	-0.1	0.3	0.4	0.0	0.5
Qualifications: A levels/AS levels or equivalent	0.2	0.5	2.0	-1.1	-0.6	-0.3	-0.8	-0.4	-0.9	-1.4	0.8	-0.5	-0.3	0.2	0.2	0.3	-0.3	0.8	-0.2	-0.1	-1.1	-1.0	-0.2	-0.7	-0.5
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	0.9	0.5	0.6	0.7	0.1	1.0	0.4	0.5	0.4	-0.6	0.2	0.5	0.7	0.3	-0.8	0.5	0.7	0.6	0.7	0.6	-0.3	0.8	0.7
Forced vital capacity (FVC), Best measure	0.2	0.8	2.1	-0.3	-1.0	-0.6	-1.5	-1.3	-0.7	-0.2	1.2	-0.8	-1.0	-1.3	-0.7	-0.9	-0.7	-0.9	-0.8	-0.8	-0.5	-1.0	-1.4	-0.1	-0.7
Body fat percentage	0.2	0.8	2.2	0.8	0.5	1.0	0.8	0.5	0.7	0.4	-0.8	1.4	1.1	0.6	1.0	1.1	1.4	1.5	1.1	0.9	0.7	0.6	0.4	0.5	0.7
Leg fat percentage (right)	0.2	0.9	5.0	-0.9	-1.0	-0.8	-0.8	-0.4	-1.0	-1.4	-2.2	0.0	-0.7	-0.9	-0.6	-0.2	-0.3	0.0	-0.6	-1.0	-1.0	-0.8	-1.2	-1.1	-0.9
Health satisfaction	0.2	0.2	0.8	-0.5	-0.3	-0.7	-0.4	-0.3	-0.5	-0.8	-0.9	-0.5	-0.2	0.2	-0.2	-0.2	-0.3	0.2	-0.5	-0.2	-0.7	-0.6	0.1	-0.7	-0.5
Number of full sisters	0.2	0.2	0.6	-0.3	-0.7	-0.3	-0.6	-0.7	-0.4	-0.6	-0.1	-0.0	-0.3	-0.8	-0.6	-0.5	-0.1	-0.2	-0.2	-0.5	-0.4	-0.2	-0.6	0.2	0.0
Long-standing illness, disability or infirmity	0.2	0.4	1.0	-0.9	-0.8	-0.5	-0.7	-0.2	-0.9	-0.8	-0.4	-0.4	-0.3	-0.6	0.1	-0.2	-0.6	0.7	-0.2	-0.4	-0.7	-0.6	-1.0	-0.8	-0.5
Friendships satisfaction	0.2	0.3	1.5	-0.3	-0.5	-0.4	-0.3	-0.8	-0.5	-0.1	0.3	0.9	0.2	-0.2	-0.3	-0.1	1.2	0.1	-0.4	-0.2	-0.5	-0.6	0.7	-0.3	-0.2
Ever taken oral contraceptive pill	0.2	0.3	1.5	0.4	-0.0	0.2	0.4	0.5	0.3	0.2	0.8	0.9	0.5	0.4	0.4	0.6	1.2	0.4	0.3	0.4	0.3	0.3	0.8	0.3	0.3
Leg fat percentage (left)	0.2	0.8	5.1	-0.8	-0.9	-0.8	-0.7	-0.3	-0.8	-1.3	-2.2	0.0	-0.7	-1.0	-0.7	-0.3	-0.3	-0.1	-0.6	-0.7	-0.9	-0.8	-1.4	-1.0	-0.9
Average weekly beer plus cider intake	0.2	0.3	1.1	0.4	-0.4	0.7	-0.0	0.4	0.3	0.3	0.1	0.4	0.6	0.8	0.7	0.6	0.5	0.9	0.7	0.5	0.4	0.5	1.0	0.5	0.7
Ever depressed for a whole week	0.2	0.2	1.3	0.5	0.8	0.1	0.4	0.1	0.3	-0.0	1.1	0.4	0.6	0.3	0.5	0.1	0.5	0.4	0.2	0.1	0.3	0.3	0.2	0.4	0.5
Basal cell carcinoma (self-reported)	0.2	0.2	1.0	-0.1	0.8	0.5	0.2	0.3	-0.2	-0.6	0.4	0.4	0.5	-0.1	0.3	0.4	-0.2	1.0	0.5	0.3	-0.2	0.6	-0.1	-0.0	0.5
Bipolar Disorder (2011)	0.1	0.1	2.4	0.0	0.0	0.0	0.0	1.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Platelet Count	0.1	1.5	7.4	1.3	0.4	0.3	0.3	1.7	1.1	0.4	-2.7	1.7	0.5	0.6	-0.5	0.1	2.5	-0.2	0.9	0.8	1.3	0.7	1.7	1.2	0.8
Tanning	0.1	0.8	2.1	0.8	0.5	0.9	1.0	0.6	1.1	1.5	0.3	0.9	0.9	-0.1	0.8	0.6	0.6	0.6	0.8	1.2	1.1	1.1	0.0	1.3	1.2
Supplements: Zinc	0.1	0.1	1.0	0.4	1.0	0.4	0.3	-0.4	0.4	0.4	0.2	0.2	0.3	-0.2	-0.1	-0.4	-0.1	-0.3	0.1	0.3	0.4	0.5	-0.2	0.5	0.4
Medication: Co-codamol	0.1	0.1	0.5	0.2	0.1	0.2	-0.3	-0.5	-0.0	-0.1	0.7	0.3	0.1	-0.4	0.0	-0.3	0.2	0.1	0.1	0.1	0.1	-0.1	-0.5	0.2	0.1
Age when periods started (menarche)	0.1	0.3	1.6	-0.2	-0.5	-0.7	-0.5	0.0	-0.2	-0.3	0.1	-0.5	-0.8	-0.3	-0.8	-0.5	-0.5	-1.3	-0.5	-0.4	-0.2	-0.3	-0.2	0.3	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	1.5	0.1	-0.1	0.5	-0.0	0.9	0.1	-0.0	0.2	-1.2	-0.5	0.5	0.5	0.3	-1.1	-0.2	0.1	0.1	0.2	-0.1	-0.6	0.3	0.1
Serious illness, injury or assault to yourself	0.1	0.1	0.4	-0.2	0.6	-0.2	0.1	-0.2	-0.1	0.2	0.1	0.3	0.3	0.2	-0.1	0.2	0.3	0.1	-0.1	0.1	-0.0	0.4	0.5	0.1	0.3
Medication: Levothyroxine sodium	0.1	0.1	1.1	0.3	0.3	-0.0	-0.3	0.7	-0.0	0.3	0.2	-0.9	-0.4	0.0	0.1	0.0	-1.0	-0.2	0.1	-0.0	0.3	0.0	-0.5	0.2	0.1
Nervous feelings	0.1	0.2	1.4	-0.2	-0.5	-0.2	-0.3	-0.4	-0.4	-0.8	-0.9	-0.8	-0.4	0.4	-0.0	0.2	-1.2	0.1	-0.1	-0.0	-0.4	-0.2	-0.2	-0.1	-0.1
Hair/balding pattern: Pattern 2	0.1	0.2	0.5	-0.6	0.2	-0.4	-0.5	-0.4	-0.3	-0.1	0.4	-0.0	-0.3	-0.7	-0.6	-0.6	-0.2	-0.4	-0.4	-0.5	-0.4	-0.2	-0.5	-0.6	-0.5
Qualifications: None of the above	0.1	0.1	0.8	-0.0	0.4	-0.1	0.7	-0.9	0.3	0.3	-0.2	0.2	0.2	-0.2	-0.2	-0.1	-0.1	-0.3	-0.3	-0.4	-0.0	0.5	-0.1	-0.4	-0.1
Pulse rate	0.1	0.2	1.7	-0.1	-1.0	-0.0	-0.4	-0.4	-0.3	-0.6	-1.3	-0.2	-0.1	0.1	0.4	0.1	-0.2	0.7	0.3	0.1	-0.1	-0.4	-0.6	-0.0	-0.0
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.6	-0.5	-0.2	0.2	-0.1	0.3	-0.4	-0.3	0.5	-0.2	-0.2	-0.5	0.1	0.0	-0.5	0.0	-0.3	-0.4	-0.4	-0.1	-0.8	0.1	0.1
Medication: Lansoprazole	0.1	0.1	0.7	0.0	0.7	-0.3	0.4	-0.6	0.1	-0.1	0.0	-0.3	-0.2	-0.1	-0.0	-0.3	-0.5	-0.1	-0.2	-0.4	-0.2	-0.1	-0.8	-0.2	-0.1
Exposure to tobacco smoke at home	0.1	0.1	0.9	-0.0	0.4	-0.2	0.4	-0.9	-0.1	-0.3	-0.5	-0.2	0.0	-0.4	-0.0	-0.5	-0.5	-0.1	-0.2	-0.3	-0.2	0.2	-0.6	-0.1	-0.0
Glaucoma (self-reported)	0.1	0.1	0.3	0.2	0.4	0.2	0.4	-0.2	0.2	0.1	0.5	-0.3	0.3	0.4	0.4	-0.0	-0.2	0.1	0.2	0.3	0.1	0.2	0.5	-0.1	0.1
Gout (self-reported)	0.1	0.1	0.4	-0.4	-0.6	0.1	-0.5	0.1	-0.6	-0.6	0.1	-0.1	-0.2	0.4	0.3	0.6	0.1	0.4	0.1	-0.3	-0.2	-0.2	0.6	0.0	0.1
Exposure to tobacco smoke outside home	0.1	0.1	0.5	0.0	0.5	0.6	0.5	-0.1	0.3	0.5	0.5	-0.1	0.5	0.5	0.7	0.2	-0.0	0.6	0.2	0.3	0.1	0.1	0.4	-0.3	0.0
Number of full brothers	0.1	0.1	0.4	-0.5	0.0	-0.1	-0.1	0.4	-0.4	0.2	-0.5	-0.1	-0.2	-0.6	-0.4	-0.5	-0.2	-0.1	-0.6	-0.4	-0.6	-0.4	-0.3	-0.2	-0.2
Eye problems/disorders: None of the above	0.1	0.1	0.3	-0.5	-0.2	-0.2	-0.4	-0.1	-0.2	-0.2	0.2	-0.1	-0.5	-0.4	-0.6	-0.0	0.2	-0.5	-0.4	-0.2	-0.3	-0.2	-0.0	-0.5	-0.4
Migraine (self-reported)	0.1	0.1	0.4	-0.2	0.2	-0.2	0.3	0.0	-0.5	-0.6	0.1	0.3	-0.3	-0.4	-0.5	0.2	-0.0	-0.1	0.0	-0.5	-0.3	0.5	-0.2	-0.2	0.1
Medication: Allopurinol	0.1	0.2	0.9	-0.1	-0.2	0.4	-0.2	0.5	-0.3	-0.7	0.2	0.5	0.3	0.2	0.6	0.8	0.5	0.9	0.5	-0.0	-0.1	0.1	0.2	0.2	0.3
Leg fat mass (right)	0.1	0.5	1.9	0.5	0.1	0.8	0.3	0.3	0.3	0.0	-0.5	1.3	0.8	0.4	0.8	1.1	1.2	1.4	0.9	0.4	0.4	0.4	0.2	0.3	0.5
Alcohol intake frequency.	0.1	0.3	1.8	-0.1	0.7	0.5	0.4	0.6	-0.0	-0.2	0.6	1.4	0.8	-0.1	0.1	0.5	1.1	0.9	0.4	0.2	-0.0	0.6	0.1	0.1	0.5
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.6	0.8	-0.3	0.3	-0.1	0.5	0.6	0.5	-0.6	-0.2	-0.1	0.5	-0.2	-0.3	0.3	-0.5	0.1	0.0	0.6	-0.0	0.5	0.2	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.7	-0.0	0.2	0.0	-0.1	-0.9	-0.0	-0.1	-0.4	-0.6	-0.1	0.2	0.6	0.2	-0.6	0.2	-0.2	0.1	-0.1	-0.4	-0.7	-0.1	-0.1
Qualifications: nursing, teaching	0.1	0.2	0.9	0.3	-0.0	0.7	-0.1	0.3	0.1	0.1	0.3	-0.1	0.4	0.5	0.7	0.7	0.1	0.9	0.7	0.8	0.4	-0.0	-0.0	0.7	0.5
Eye problems/disorders: Cataract	0.1	0.1	0.4	0.1	-0.3	0.0	0.0	0.2	0.0	0.0	-0.6	0.5	0.2	0.1	0.4	0.1	0.5	0.5	0.1	-0.1	-0.0	-0.4	-0.1	0.2	0.1
Back pain experienced in last month	0.1	0.1	0.8	-0.5	-0.1	0.2	0.0	-0.2	-0.5	0.1	0.9	0.4	0.1	-0.5	0.2	0.3	0.3	0.6	-0.0	-0.4	-0.4	-0.2	-0.4	-0.3	0.1
Eye problems/disorders: Glaucoma	0.1	0.1	0.4	-0.1	0.1	-0.2	-0.1	-0.6	-0.2	-0.4	0.6	-0.3	-0.0	-0.4	-0.1	-0.4	-0.5	-0.1	-0.1	-0.0	-0.2	0.0	0.0	0.0	0.0
Leg fat mass (left)	0.1	0.5	1.8	0.6	0.2	0.8	0.4	0.4	0.5	0.1	-0.5	1.4	0.9	0.4	0.8	1.0	1.2	1.3	0.9	0.6	0.5	0.4	0.1	0.4	0.6
Heel T-Score	0.0	0.4	1.0	-0.8	-0.8	1.0	0.2	0.6	-0.7	-0.3	0.8	-0.6	-0.0	0.0	0.8	0.7	-0.7	0.9	-0.1	-0.3	-0.6	-0.4	-0.7	-0.5	-0.1
Lung FEV1/FVC ratio	0.0	0.1	0.2	-0.1	0.5	0.1	0.3	0.5	0.0	-0.2	0.4	-0.0	-0.1	0.1	0.2	0.2	0.2	0.2	0.2	0.2	0.0	-0.1	0.2	-0.2	-0.1
Impedance of arm (right)	0.0	0.2	0.6	-0.7	0.2	-0.3	-0.2	-0.4	-0.6	-0.6	0.6	-0.3	-0.4	-0.2	-0.5	-0.2	-0.4	-0.1	-0.4	-0.4	-0.7	-0.2	0.2	-0.7	-0.5
Hip circumference	0.0	0.1	0.8	0.2	-0.4	0.3	-0.2	-0.9	-0.1	-0.1	-0.4	0.5	0.2	-0.2	0.2	0.2	0.3	0.6	0.2	0.0	-0.0	-0.2	-0.2	-0.1	-0.1
Impedance of arm (left)	0.0	0.1	0.4	-0.2	0.6	-0.1	0.3	0.0	-0.0	0.2	0.6	0.1	-0.0	-0.1	-0.4	-0.2	0.2	-0.2	-0.1	-0.0	-0.2	0.1	0.5	-0.5	-0.3

Hub : Genes

FES

Models

Trait associations