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chr7:6,502,367-7,988,091

Best TWAS P=1.56e-13 · Best GWAS P=4.91e-10 conditioned to 0.101

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	C1GALT1	0.26	0.15	enet	20	0.23	1.1e-27	4.2	6.5	8.4e-11	0.67	0.45	0.55	FALSE
2	GTEx	Brain Caudate basal ganglia	C1GALT1	0.27	0.18	enet	8	0.20	2.4e-06	6.1	6.1	9.7e-10	0.79	0.01	0.98	FALSE
3	GTEx	Brain Cerebellar Hemisphere	C1GALT1	0.33	0.24	lasso	4	0.20	6.1e-06	6.0	5.8	5.0e-09	0.92	0.01	0.98	FALSE
4	GTEx	Brain Cortex	C1GALT1	0.32	0.10	lasso	13	0.13	1.9e-04	6.1	5.8	7.1e-09	0.62	0.02	0.94	FALSE
5	GTEx	Brain Nucleus accumbens basal ganglia	C1GALT1	0.28	0.00	enet	28	0.01	1.8e-01	6.1	6.2	6.0e-10	0.70	0.02	0.85	FALSE
6	GTEx	Breast Mammary Tissue	C1GALT1	0.23	0.15	lasso	8	0.15	5.1e-08	5.8	5.7	1.1e-08	0.69	0.01	0.99	FALSE
7	GTEx	Breast Mammary Tissue (Male)	C1GALT1	0.00	0.03	lasso	1	0.09	4.0e-03	5.8	5.8	6.3e-09	0.68	0.04	0.27	FALSE
8	GTEx	Cells Transformed fibroblasts	C1GALT1	0.12	0.03	lasso	3	0.05	1.0e-04	4.3	5.6	2.3e-08	0.61	0.04	0.90	FALSE
9	GTEx	Colon Sigmoid	C1GALT1	0.52	0.25	enet	38	0.31	1.0e-11	6.1	5.6	1.7e-08	0.65	0.01	0.99	FALSE
10	GTEx	Colon Transverse	C1GALT1	0.32	0.23	lasso	4	0.30	8.0e-15	5.9	6.4	1.2e-10	0.90	0.01	0.99	FALSE
11	GTEx	Esophagus Mucosa	C1GALT1	0.33	0.19	lasso	6	0.18	2.8e-12	6.2	6.6	4.0e-11	0.94	0.00	1.00	FALSE
12	GTEx	Esophagus Muscularis	C1GALT1	0.36	0.16	lasso	8	0.27	1.9e-16	5.5	6.6	5.1e-11	0.80	0.04	0.96	FALSE
13	GTEx	Heart Left Ventricle	C1GALT1	0.17	0.04	enet	23	0.05	1.5e-03	6.2	7.4	1.6e-13	0.68	0.01	0.96	TRUE
14	GTEx	Lung	C1GALT1	0.18	0.13	lasso	3	0.15	1.1e-11	5.5	6.8	7.8e-12	0.73	0.03	0.97	FALSE
15	GTEx	Nerve Tibial	C1GALT1	0.44	0.28	lasso	12	0.40	2.0e-30	4.3	6.3	2.4e-10	0.81	0.06	0.94	FALSE
16	GTEx	Ovary	C1GALT1	0.22	0.14	enet	11	0.15	1.8e-04	6.1	5.8	8.0e-09	0.86	0.01	0.95	FALSE
17	GTEx	Pancreas	C1GALT1	0.44	0.11	enet	24	0.22	8.8e-10	4.3	6.3	2.6e-10	0.78	0.04	0.96	FALSE
18	GTEx	Skin Sun Exposed Lower leg	C1GALT1	0.22	0.04	lasso	9	0.10	4.8e-09	6.0	6.6	3.9e-11	0.72	0.02	0.98	FALSE
19	GTEx	Stomach	C1GALT1	0.24	0.07	enet	17	0.12	1.9e-06	5.8	6.3	3.0e-10	0.79	0.02	0.98	FALSE
20	GTEx	Thyroid	C1GALT1	0.30	0.27	lasso	3	0.31	3.9e-24	4.3	5.6	2.6e-08	0.63	0.97	0.03	FALSE
21	GTEx	Uterus	C1GALT1	0.38	0.28	enet	8	0.32	2.0e-07	5.9	6.3	2.8e-10	0.85	0.02	0.96	FALSE
22	METSIM	Adipose	C1GALT1	0.22	0.16	lasso	9	0.23	5.1e-34	6.1	6.6	3.8e-11	0.75	0.01	0.99	FALSE
23	YFS	Blood	C1GALT1	0.35	0.20	enet	45	0.32	4.3e-109	5.5	5.4	5.9e-08	0.59	0.17	0.83	FALSE
24	The Cancer Genome Atlas	Breast Invasive Carcinoma	C1GALT1	0.02	0.01	lasso	4	0.01	1.7e-02	4.2	5.1	2.9e-07	0.60	0.08	0.57	FALSE
25	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C1GALT1	0.16	0.12	lasso	7	0.14	3.7e-08	5.9	6.7	2.4e-11	0.87	0.00	1.00	FALSE
26	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C1GALT1	0.27	0.06	enet	22	0.10	8.1e-05	5.8	6.3	3.3e-10	0.68	0.02	0.94	FALSE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	C1GALT1	0.12	0.05	enet	10	0.13	9.9e-14	4.2	5.2	2.3e-07	0.72	0.21	0.79	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	C1GALT1	0.05	0.01	lasso	2	0.01	3.8e-02	5.8	6.1	8.1e-10	0.72	0.01	0.86	FALSE