[Hub]/) : Traits : High blood pressure :

chr7:6,502,367-7,988,091

Best TWAS P=1.56e-13 · Best GWAS P=4.91e-10 conditioned to 0.101

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C1GALT1 0.26 0.15 enet 20 0.23 1.1e-27 4.2 6.5 8.4e-11 0.67 0.45 0.55 FALSE
2 GTEx Brain Caudate basal ganglia C1GALT1 0.27 0.18 enet 8 0.20 2.4e-06 6.1 6.1 9.7e-10 0.79 0.01 0.98 FALSE
3 GTEx Brain Cerebellar Hemisphere C1GALT1 0.33 0.24 lasso 4 0.20 6.1e-06 6.0 5.8 5.0e-09 0.92 0.01 0.98 FALSE
4 GTEx Brain Cortex C1GALT1 0.32 0.10 lasso 13 0.13 1.9e-04 6.1 5.8 7.1e-09 0.62 0.02 0.94 FALSE
5 GTEx Brain Nucleus accumbens basal ganglia C1GALT1 0.28 0.00 enet 28 0.01 1.8e-01 6.1 6.2 6.0e-10 0.70 0.02 0.85 FALSE
6 GTEx Breast Mammary Tissue C1GALT1 0.23 0.15 lasso 8 0.15 5.1e-08 5.8 5.7 1.1e-08 0.69 0.01 0.99 FALSE
7 GTEx Breast Mammary Tissue (Male) C1GALT1 0.00 0.03 lasso 1 0.09 4.0e-03 5.8 5.8 6.3e-09 0.68 0.04 0.27 FALSE
8 GTEx Cells Transformed fibroblasts C1GALT1 0.12 0.03 lasso 3 0.05 1.0e-04 4.3 5.6 2.3e-08 0.61 0.04 0.90 FALSE
9 GTEx Colon Sigmoid C1GALT1 0.52 0.25 enet 38 0.31 1.0e-11 6.1 5.6 1.7e-08 0.65 0.01 0.99 FALSE
10 GTEx Colon Transverse C1GALT1 0.32 0.23 lasso 4 0.30 8.0e-15 5.9 6.4 1.2e-10 0.90 0.01 0.99 FALSE
11 GTEx Esophagus Mucosa C1GALT1 0.33 0.19 lasso 6 0.18 2.8e-12 6.2 6.6 4.0e-11 0.94 0.00 1.00 FALSE
12 GTEx Esophagus Muscularis C1GALT1 0.36 0.16 lasso 8 0.27 1.9e-16 5.5 6.6 5.1e-11 0.80 0.04 0.96 FALSE
13 GTEx Heart Left Ventricle C1GALT1 0.17 0.04 enet 23 0.05 1.5e-03 6.2 7.4 1.6e-13 0.68 0.01 0.96 TRUE
14 GTEx Lung C1GALT1 0.18 0.13 lasso 3 0.15 1.1e-11 5.5 6.8 7.8e-12 0.73 0.03 0.97 FALSE
15 GTEx Nerve Tibial C1GALT1 0.44 0.28 lasso 12 0.40 2.0e-30 4.3 6.3 2.4e-10 0.81 0.06 0.94 FALSE
16 GTEx Ovary C1GALT1 0.22 0.14 enet 11 0.15 1.8e-04 6.1 5.8 8.0e-09 0.86 0.01 0.95 FALSE
17 GTEx Pancreas C1GALT1 0.44 0.11 enet 24 0.22 8.8e-10 4.3 6.3 2.6e-10 0.78 0.04 0.96 FALSE
18 GTEx Skin Sun Exposed Lower leg C1GALT1 0.22 0.04 lasso 9 0.10 4.8e-09 6.0 6.6 3.9e-11 0.72 0.02 0.98 FALSE
19 GTEx Stomach C1GALT1 0.24 0.07 enet 17 0.12 1.9e-06 5.8 6.3 3.0e-10 0.79 0.02 0.98 FALSE
20 GTEx Thyroid C1GALT1 0.30 0.27 lasso 3 0.31 3.9e-24 4.3 5.6 2.6e-08 0.63 0.97 0.03 FALSE
21 GTEx Uterus C1GALT1 0.38 0.28 enet 8 0.32 2.0e-07 5.9 6.3 2.8e-10 0.85 0.02 0.96 FALSE
22 METSIM Adipose C1GALT1 0.22 0.16 lasso 9 0.23 5.1e-34 6.1 6.6 3.8e-11 0.75 0.01 0.99 FALSE
23 YFS Blood C1GALT1 0.35 0.20 enet 45 0.32 4.3e-109 5.5 5.4 5.9e-08 0.59 0.17 0.83 FALSE
24 The Cancer Genome Atlas Breast Invasive Carcinoma C1GALT1 0.02 0.01 lasso 4 0.01 1.7e-02 4.2 5.1 2.9e-07 0.60 0.08 0.57 FALSE
25 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C1GALT1 0.16 0.12 lasso 7 0.14 3.7e-08 5.9 6.7 2.4e-11 0.87 0.00 1.00 FALSE
26 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma C1GALT1 0.27 0.06 enet 22 0.10 8.1e-05 5.8 6.3 3.3e-10 0.68 0.02 0.94 FALSE
27 The Cancer Genome Atlas Prostate Adenocarcinoma C1GALT1 0.12 0.05 enet 10 0.13 9.9e-14 4.2 5.2 2.3e-07 0.72 0.21 0.79 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma C1GALT1 0.05 0.01 lasso 2 0.01 3.8e-02 5.8 6.1 8.1e-10 0.72 0.01 0.86 FALSE