Hub : Traits :

High blood pressure

1217 significantly associated models · 361 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 7715776 9571422 2 1 2.2e-08 6.7e-08 2.9e-01 96 RP5-1115A15.1
2 1 10435170 12600396 7 7 5.2e-28 9.5e-31 7.3e-03 95 CLCN6 MTHFR NPPA-AS1 RP4-635E18.7
3 1 26428864 28406173 4 2 3.2e-09 3.6e-07 4.8e-01 98 FCN3 PIGV
4 1 88621347 90053563 1 1 1.5e-10 2.5e-10 1.2e-01 94 GTF2B
5 1 112312154 113941737 5 3 3.5e-17 1.8e-20 5.8e-08 66 RHOC RP4-671G15.2 WNT2B
6 1 115136771 116579779 1 1 1.2e-07 1.5e-11 1.1e-10 9 NGF
7 1 230142626 231548480 1 1 6.4e-12 3.7e-10 6.4e-02 91 AGT
8 2 24021231 26068509 4 1 7.9e-11 5.6e-10 3.1e-02 88 NCOA1
9 2 26223547 27689899 2 2 1.7e-08 2.0e-33 1.3e-24 28 KCNK3 SLC35F6
10 2 36778887 38298877 2 1 6.8e-10 3.6e-09 1.0e+00 100 PRKD3
11 2 181139278 184084221 2 2 7.7e-08 3.7e-08 1.1e-11 -52 PDE1A UBE2E3
12 3 10617048 12293966 1 1 3.9e-08 1.7e-10 9.1e-04 73 ATG7
13 3 19382787 20893060 2 1 3.5e-08 1.3e-08 7.1e-02 90 KAT2B
14 3 26563909 28211713 2 2 1.1e-16 4.2e-18 4.1e-02 94 SLC4A7
15 3 47204518 49365269 7 1 3.7e-11 2.5e-11 1.0e+00 100 FCF1P2
16 3 127097277 128821807 2 1 1.1e-07 5.8e-09 2.4e-03 73 RUVBL1
17 3 133088362 134666475 1 1 2.5e-07 8.1e-10 5.9e-04 69 RYK
18 3 137189600 138819532 2 1 1.1e-08 9.0e-09 2.3e-01 96 DBR1
19 3 157125828 158980014 2 1 7.3e-09 1.3e-07 2.9e-01 96 RP11-538P18.2
20 3 183204923 184607480 1 1 1.0e-07 3.4e-07 3.9e-01 97 ABCF3
21 4 17104059 18507692 2 1 1.8e-09 4.3e-09 1.8e-02 84 DCAF16
22 4 25880334 27452482 1 2 1.6e-11 1.2e-14 2.0e-09 40 TBC1D19
23 4 80407869 82578407 3 2 4.3e-20 1.1e-65 1.8e-42 36 C4orf22 PRDM8
24 4 102868793 104627833 5 1 2.3e-11 3.7e-10 8.2e-01 100 CISD2
25 4 110590479 112179424 1 1 2.9e-07 6.4e-13 5.9e-09 34 ENPEP
26 4 155890241 157354250 2 1 2.2e-08 6.7e-12 8.1e-11 10 RP11-588K22.2
27 5 32015725 33484084 1 1 1.1e-07 7.3e-31 5.4e-25 20 NPR3
28 5 60903201 62529686 2 1 4.0e-08 9.8e-08 4.0e-02 85 IPO11
29 5 130830617 132425049 8 1 1.4e-08 4.4e-08 2.1e-01 95 PDLIM4
30 6 14551209 16209635 1 1 2.5e-07 6.9e-07 1.1e-02 74 JARID2
31 6 42586058 44034691 2 1 8.1e-13 2.6e-13 1.0e+00 100 ZNF318
32 6 78946797 80486611 1 1 6.2e-08 3.1e-07 4.7e-01 98 PHIP
33 6 96275538 97699026 1 1 1.5e-07 7.3e-08 1.5e-01 93 UFL1
34 6 117187910 118613435 1 1 1.5e-07 4.4e-10 4.3e-10 0 GOPC
35 6 125970401 127355237 1 1 4.8e-09 1.2e-30 2.6e-24 22 CENPW
36 7 1854263 3264728 1 1 2.6e-10 4.5e-10 1.0e+00 100 LFNG
37 7 6502367 7988091 1 1 1.6e-13 4.9e-10 1.0e-01 93 C1GALT1
38 7 26969253 27533292 2 1 1.8e-15 1.9e-17 1.0e-03 85 HOXA10
39 7 73425238 75714883 6 2 6.9e-09 1.6e-08 3.8e-01 98 PMS2P5 STAG3L1
40 7 76506844 77966572 1 1 1.1e-07 8.0e-07 6.8e-02 86 PTPN12
41 7 99122437 100516003 1 1 7.2e-08 4.3e-07 5.1e-01 98 PVRIG
42 7 129342404 130779678 2 2 1.5e-08 1.2e-12 1.1e-05 62 CEP41 ZC3HC1
43 7 132241297 134834499 3 2 1.1e-07 8.6e-08 3.8e-01 97 AKR1B15 EXOC4
44 8 8092025 13120332 26 2 8.2e-16 8.2e-14 6.2e-04 79 MSRA NEIL2
45 8 29996824 31433801 1 1 6.3e-08 2.0e-08 1.3e-01 93 TEX15
46 8 90238179 91633434 1 1 2.1e-07 4.7e-08 4.2e-02 86 OSGIN2
47 8 95213858 96825195 1 1 1.3e-07 1.1e-06 3.6e-01 96 NDUFAF6
48 8 102002608 103832256 2 1 3.3e-09 9.5e-10 5.4e-04 68 KB-1107E3.1
49 9 221874 991114 1 1 2.6e-07 9.6e-08 2.3e-03 67 KANK1
50 9 35208145 36597142 1 1 6.3e-09 1.1e-08 2.1e-04 58 HRCT1
51 9 135883620 136399075 1 1 1.0e-09 1.2e-08 5.5e-01 99 ABO
52 10 18221643 19601824 2 2 8.8e-13 1.2e-16 5.2e-14 17 CACNB2 NSUN6
53 10 60026425 60829144 1 1 5.1e-08 2.5e-07 1.2e-01 91 BICC1
54 10 63856856 65606229 3 3 9.9e-13 6.7e-12 3.3e-01 98 NRBF2 RP11-436D10.3
55 10 87729214 88960852 1 1 2.5e-07 4.1e-07 7.0e-02 87 LDB3
56 10 95379543 96818402 1 1 1.9e-10 8.0e-13 1.2e-04 71 NOC3L
57 10 103313599 105850787 9 1 1.3e-14 3.0e-16 6.6e-03 89 NT5C2
58 10 115244596 116689519 3 3 2.3e-13 1.7e-21 1.6e-09 60 ADRB1 C10orf118 TDRD1
59 10 133777786 134395804 1 1 1.2e-07 2.8e-07 7.6e-07 7 STK32C
60 11 1213806 2705175 5 5 1.0e-20 3.5e-23 NaN NaN LSP1 TNNI2 TNNT3
61 11 9003306 10471931 1 1 1.0e-08 1.2e-11 1.2e-04 68 SWAP70
62 11 15741673 18106069 4 2 8.7e-09 8.5e-18 2.1e-10 45 NUCB2 SOX6
63 11 42881882 44596817 2 1 6.9e-08 2.4e-09 7.2e-03 80 RP11-613D13.5
64 11 46010847 48783497 20 1 4.2e-25 1.8e-20 5.7e-07 71 ACP2
65 11 56370106 57784307 1 1 2.7e-07 1.2e-08 1.1e-05 41 TNKS1BP1
66 11 64721908 66333072 3 1 7.4e-11 5.7e-12 4.3e-06 56 RNASEH2C
67 11 99859184 101559718 2 1 2.7e-35 1.4e-33 1.8e-01 99 TMEM133
68 11 106485489 108027561 2 1 4.7e-10 1.1e-10 1.3e-02 85 CWF19L2
69 11 110721187 112491227 5 1 3.1e-10 3.1e-10 1.0e+00 100 SIK2
70 12 26480758 27916206 1 1 1.7e-07 6.1e-07 1.0e+00 100 MED21
71 12 47737273 49444545 3 2 6.3e-09 1.3e-09 2.5e-01 96 HDAC7 SENP1
72 12 49780778 51256065 4 1 9.0e-11 4.5e-13 1.6e-10 22 CERS5
73 12 54158993 54760824 4 1 1.2e-11 1.6e-12 3.6e-02 91 HOXC8
74 12 66965631 68410906 1 1 3.4e-08 3.4e-08 1.0e+00 100 CAND1
75 12 69057879 70476863 1 1 1.2e-08 6.8e-08 1.0e+00 100 YEATS4
76 12 89116708 90799212 3 2 5.3e-16 3.8e-25 2.6e-13 50 ATP2B1 LOC338758
77 12 109591369 111015121 2 1 1.0e-08 2.2e-08 1.4e-01 93 GLTP
78 12 111102574 113517494 16 1 3.8e-21 7.3e-29 3.5e-11 65 SH2B3
79 12 121146219 123131824 3 3 1.7e-15 3.1e-15 1.0e+00 100 KDM2B RNF34 WDR66
80 15 40360741 42749023 8 1 4.6e-11 2.9e-11 9.9e-02 94 CHP1
81 15 67138238 68789191 1 1 8.9e-08 1.7e-08 3.3e-02 86 MAP2K5
82 15 73933444 76108550 14 10 2.4e-23 7.1e-23 1.0e+00 100 ARID3B COX5A CSK MPI RPP25 UBL7 ULK3
83 15 80377452 81936479 2 1 2.0e-11 1.2e-14 1.0e-04 75 FAM108C1
84 15 90712555 92187978 3 3 1.1e-38 8.7e-29 5.9e-01 100 FES FURIN
85 16 3025993 5441125 4 3 8.6e-11 1.8e-09 1.7e-06 36 AC006111.1 MGRN1 NAT15
86 16 29412503 31860399 16 2 7.1e-10 3.2e-09 6.5e-02 90 FAM57B KAT8
87 16 69337091 70978362 3 1 1.4e-07 5.0e-07 3.7e-01 97 RP11-296I10.6
88 16 74778006 76197034 1 1 1.5e-07 5.7e-06 9.5e-01 100 TMEM170A
89 16 81230341 81993974 1 1 4.2e-14 1.1e-13 2.9e-04 76 CMIP
90 16 89013848 90172696 9 8 6.9e-13 9.0e-13 NaN NaN CHMP1A DEF8 DPEP1 SPATA33
91 17 1517914 2918626 1 1 1.2e-07 1.3e-08 1.1e-03 67 SRR
92 17 3208350 4766937 2 1 3.1e-09 1.2e-08 3.5e-01 97 RP11-810M2.2
93 17 6202301 8484683 10 4 6.7e-12 6.7e-12 1.0e+00 100 ALOX12 CYB5D1 SENP3 SLC2A4
94 17 42976114 43383100 1 1 6.2e-08 1.2e-06 8.1e-02 87 HEXIM1
95 17 44788310 45597098 2 1 1.3e-07 2.9e-12 4.2e-12 2 WNT3
96 17 46258510 47718188 8 3 5.6e-12 2.4e-15 3.7e-05 73 AC091133.1 HOXB9 ZNF652
97 17 60858059 62279811 2 1 1.3e-15 1.3e-15 1.0e+00 100 ACE
98 17 73175294 74629867 3 1 1.2e-08 1.9e-08 2.0e-01 95 FBF1
99 19 1163934 2560423 3 2 1.4e-09 1.5e-09 1.0e+00 100 CTB-31O20.6 KLF16
100 19 16462417 18007950 3 2 1.5e-12 1.7e-13 2.2e-03 83 HAUS8 MYO9B
101 19 49148143 50557876 1 1 1.7e-07 7.6e-07 2.4e-02 79 TEAD2
102 20 7419920 9648826 1 2 1.4e-10 3.4e-19 3.1e-07 67 PLCB1
103 20 29927166 31615615 3 2 8.1e-09 8.8e-08 7.0e-06 29 C20orf160 TSPY26P
104 20 42040938 43508687 1 1 8.2e-08 2.4e-11 5.0e-06 53 JPH2
105 20 56858751 58262841 4 6 5.6e-18 1.4e-33 NaN NaN NELFCD TH1L TUBB1 ZNF831
106 20 61522825 62912463 8 4 2.5e-12 4.7e-12 1.0e+00 100 LIME1 RGS19 TPD52L2 ZBTB46
107 21 44512286 45879403 2 1 7.0e-08 2.5e-08 1.0e+00 100 PDXK
108 22 28794069 30261219 4 2 1.0e-12 6.7e-08 5.5e-01 99 C22orf31 ZNRF3

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Bipolar Disorder (2018) 1.91 2 0 0.0 0.00 1.0e+00 SPATA33 ZC3HC1
Bipolar Disorder or Schizophrenia 2.10 11 4 8.9 -0.47 1.0e-01 CERS5 CHMP1A CLCN6 DPEP1 FAM57B FES FURIN NSUN6 NT5C2 SPATA33 TBC1D19
Depressed Affect (Nagel 2018) 1.17 5 3 6.7 -0.50 3.9e-01 ACP2 OSGIN2 RP5-1115A15.1 SH2B3 WNT3
Depression (Nagel 2018) 1.24 1 0 0.0 0.00 1.0e+00 RP5-1115A15.1
Intelligence (Savage-Jansen 2018) 1.05 3 1 2.2 0.00 1.0e+00 DCAF16 GTF2B NRBF2
Neuroticism (Nagel 2018) 1.12 5 2 4.4 -0.39 5.1e-01 ACP2 FURIN KAT8 RP5-1115A15.1 WNT3
Schizophrenia (2018) 1.82 5 3 6.7 -0.52 2.9e-01 FAM57B FES FURIN NT5C2 TBC1D19
Worry (Nagel 2018) 1.24 3 2 4.4 0.00 1.0e+00 KAT8 NT5C2 STK32C
Alzheimer’s Disease (including proxy) 1.44 4 2 4.4 -0.99 7.2e-03 ACE KAT8 PRKD3 PVRIG
Crohns Disease (2017) 1.39 3 2 4.4 0.00 1.0e+00 PDLIM4 PMS2P5 RP11-436D10.3
Irritable Bowel Disease (IBD) 1.41 5 2 4.4 0.12 8.5e-01 LSP1 PDLIM4 PMS2P5 RP11-436D10.3 TNNI2
Ulcerative Colitis (UC) 1.19 3 1 2.2 0.00 1.0e+00 LSP1 RGS19 TNNI2
Major Depression (MDD) 1.13 1 0 0.0 0.00 1.0e+00 FES
Reaction Time 1.04 1 1 2.2 0.00 1.0e+00 SH2B3
Verbal and Numeric Reasoning (VNR) 1.02 2 1 2.2 0.00 1.0e+00 DCAF16 TEX15
Breast Cancer 2.33 10 3 6.7 0.62 2.3e-02 CSK FES FURIN LSP1 PDLIM4 PMS2P5 RP11-436D10.3 SIK2 SLC4A7 UBL7
Ovarian Cancer 1.12 2 0 0.0 0.00 1.0e+00 ABO WNT3
Prostate Cancer 1.56 2 1 2.2 0.00 1.0e+00 RUVBL1 TNNT3
Body Mass Index (BMI) (2010) 1.60 2 1 2.2 0.00 1.0e+00 MAP2K5 STAG3L1
Coronary Artery Disease (CAD) 2.08 3 2 4.4 0.00 1.0e+00 ABO DBR1 SH2B3
Crohns Disease (2012) 1.30 2 1 2.2 0.00 1.0e+00 PDLIM4 RP11-436D10.3
Fasting Glucose 1.53 1 1 2.2 0.00 1.0e+00 ACP2
HDL Cholesterol 1.37 4 1 2.2 -0.70 3.0e-01 ACP2 ADRB1 PIGV RNASEH2C
LDL Cholesterol 1.53 3 1 2.2 0.00 1.0e+00 ABO PIGV SH2B3
Neuroticism (2016) 1.25 2 0 0.0 0.00 1.0e+00 MSRA NEIL2
Primary Biliary Cirrhosis 1.23 2 1 2.2 0.00 1.0e+00 CISD2 SH2B3
Rheumatoid Arthritis 0.95 1 0 0.0 0.00 1.0e+00 SH2B3
Schizophrenia (2014) 1.91 9 3 6.7 -0.46 1.8e-01 CERS5 DPEP1 FAM57B FES FURIN NSUN6 NT5C2 NUCB2 RP5-1115A15.1
Triglycerides 1.39 3 0 0.0 -0.40 6.0e-01 KAT8 NEIL2 NRBF2
Ulcerative Colitis 1.41 2 0 0.0 0.00 1.0e+00 LSP1 TNNI2
Blood Eosinophil Count 2.61 22 13 28.9 0.59 3.8e-03 ABO CERS5 FAM57B FBF1 GLTP KAT8 NAT15 NDUFAF6 NUCB2 PDLIM4 PDXK PIGV RP5-1115A15.1 SH2B3 SIK2 SLC2A4 STK32C TSPY26P WNT3 ZC3HC1 ZNF652 ZNF831
Blood Platelet Count 3.14 44 33 73.3 -0.30 3.7e-02 ABCF3 AC091133.1 C20orf160 CERS5 COX5A CSK CWF19L2 DCAF16 FBF1 GTF2B HAUS8 HDAC7 HEXIM1 LFNG LIME1 MGRN1 MPI MTHFR MYO9B NELFCD NRBF2 NUCB2 PDLIM4 PHIP PIGV RHOC RNASEH2C RP11-436D10.3 RP4-671G15.2 RPP25 RUVBL1 SENP1 SH2B3 SIK2 SLC4A7 SWAP70 TH1L TMEM170A TNKS1BP1 TNNT3 TUBB1 UBL7 ZC3HC1 ZNF318
Blood Red Count 1.89 45 25 55.6 0.31 3.0e-02 ABO ARID3B BICC1 C20orf160 C4orf22 CENPW CHMP1A CLCN6 COX5A CSK CYB5D1 DEF8 FAM57B FBF1 GTF2B HEXIM1 HOXB9 IPO11 KAT8 LSP1 MAP2K5 MGRN1 MPI MTHFR NCOA1 NDUFAF6 NELFCD NPPA-AS1 NRBF2 NT5C2 PDXK PVRIG RNASEH2C RPP25 SENP1 SH2B3 SLC35F6 SPATA33 TDRD1 TH1L TSPY26P TUBB1 UBE2E3 UBL7 WNT3
Blood White Count 1.96 27 13 28.9 0.53 3.1e-03 ABO C10orf118 CERS5 CMIP CYB5D1 DCAF16 FES FURIN GTF2B HOXC8 KAT2B KB-1107E3.1 KCNK3 LSP1 MGRN1 NRBF2 NT5C2 PDLIM4 PLCB1 RP5-1115A15.1 SH2B3 SRR TEX15 TMEM133 TNNI2 UBE2E3 ZNF652
Heel T-Score 1.82 38 27 60.0 -0.17 2.9e-01 ABO ACP2 ATG7 BICC1 C20orf160 CHMP1A CMIP CYB5D1 DCAF16 FAM57B GTF2B HEXIM1 KAT8 LFNG LOC338758 NCOA1 NELFCD NT5C2 PDE1A PMS2P5 RHOC RNASEH2C RP11-810M2.2 RP4-635E18.7 RP4-671G15.2 RP5-1115A15.1 SENP3 SLC2A4 SOX6 STK32C TH1L TMEM133 TUBB1 UBE2E3 WNT2B WNT3 ZNF318 ZNRF3
BMI 2.08 33 23 51.1 0.69 6.3e-06 AC091133.1 C20orf160 C4orf22 CEP41 CHP1 CISD2 COX5A CTB-31O20.6 EXOC4 FAM108C1 FAM57B KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 MAP2K5 NRBF2 NT5C2 PMS2P5 RNF34 RP11-296I10.6 RP11-538P18.2 RP11-613D13.5 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEAD2 TEX15 TSPY26P
Height 1.74 55 42 93.3 -0.31 2.0e-02 ABO AC091133.1 ACE ACP2 ADRB1 ARID3B BICC1 CENPW CERS5 CHMP1A CHP1 DBR1 DCAF16 DEF8 FAM57B FES FURIN GOPC GTF2B HEXIM1 HRCT1 KANK1 LSP1 MGRN1 NAT15 NCOA1 NPR3 NRBF2 NT5C2 NUCB2 PDE1A PDLIM4 PIGV PTPN12 RHOC RP11-436D10.3 RP11-538P18.2 RP11-810M2.2 RP4-635E18.7 RP4-671G15.2 RP5-1115A15.1 RYK SENP3 SH2B3 SLC35F6 SLC4A7 STAG3L1 TMEM133 TMEM170A TNKS1BP1 WDR66 WNT2B ZNF318 ZNF652 ZNF831
Waist Hip Ratio (WHR) 1.52 18 9 20.0 0.44 6.9e-02 C22orf31 CEP41 CMIP DBR1 GTF2B HAUS8 HOXC8 MYO9B NCOA1 PTPN12 RGS19 RNASEH2C SIK2 SWAP70 TBC1D19 WNT3 ZNF318 ZNRF3
Systolic Blood Pressure 13.11 132 109 242.2 0.96 4.1e-85 ABCF3 AC006111.1 AC091133.1 ACE ACP2 ADRB1 AGT AKR1B15 ALOX12 ARID3B ATG7 ATP2B1 BICC1 C10orf118 C1GALT1 C20orf160 C22orf31 C4orf22 CACNB2 CENPW CERS5 CHMP1A CHP1 CLCN6 CMIP COX5A CSK CTB-31O20.6 CWF19L2 CYB5D1 DBR1 DCAF16 ENPEP EXOC4 FAM108C1 FBF1 FCF1P2 FCN3 FES FURIN GLTP GOPC GTF2B HAUS8 HDAC7 HEXIM1 HOXA10 HOXB9 HOXC8 HRCT1 IPO11 JPH2 KANK1 KAT2B KB-1107E3.1 KDM2B KLF16 LDB3 LFNG LIME1 LOC338758 LSP1 MED21 MGRN1 MPI MTHFR MYO9B NAT15 NCOA1 NDUFAF6 NEIL2 NELFCD NOC3L NPPA-AS1 NPR3 NRBF2 NSUN6 NT5C2 NUCB2 PDE1A PDXK PHIP PIGV PLCB1 PRDM8 PRKD3 PTPN12 RGS19 RHOC RNASEH2C RNF34 RP11-296I10.6 RP11-436D10.3 RP11-538P18.2 RP11-588K22.2 RP4-635E18.7 RP4-671G15.2 RP5-1115A15.1 RPP25 RUVBL1 RYK SENP1 SENP3 SH2B3 SIK2 SLC2A4 SLC4A7 SOX6 SPATA33 SRR STAG3L1 SWAP70 TBC1D19 TH1L TMEM133 TMEM170A TNNI2 TNNT3 TPD52L2 TUBB1 UBL7 UFL1 ULK3 WDR66 WNT2B WNT3 ZBTB46 ZC3HC1 ZNF318 ZNF652 ZNF831 ZNRF3
Smoking Status 1.25 6 0 0.0 -0.01 9.9e-01 FAM108C1 FES MAP2K5 RP5-1115A15.1 SRR ZNF652
Allergy or Eczema 2.01 15 6 13.3 0.13 6.5e-01 ABO CHP1 CLCN6 HDAC7 HEXIM1 LIME1 MPI NRBF2 PDLIM4 PDXK RNF34 RP5-1115A15.1 SIK2 SRR ZNF652
Cardiovascular Disease 12.76 145 113 251.1 0.99 3.4e-146 ABCF3 AC006111.1 AC091133.1 ACE ACP2 ADRB1 AGT AKR1B15 ARID3B ATG7 ATP2B1 BICC1 C10orf118 C1GALT1 C20orf160 C22orf31 C4orf22 CACNB2 CAND1 CENPW CEP41 CERS5 CHMP1A CHP1 CISD2 CLCN6 CMIP COX5A CSK CTB-31O20.6 CWF19L2 CYB5D1 DBR1 DCAF16 DEF8 DPEP1 ENPEP EXOC4 FAM108C1 FAM57B FBF1 FCF1P2 FCN3 FES FURIN GLTP GOPC GTF2B HAUS8 HEXIM1 HOXA10 HOXB9 HOXC8 HRCT1 IPO11 JARID2 KAT2B KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 LDB3 LFNG LIME1 LOC338758 LSP1 MAP2K5 MED21 MGRN1 MPI MTHFR MYO9B NAT15 NCOA1 NDUFAF6 NELFCD NGF NOC3L NPPA-AS1 NPR3 NRBF2 NSUN6 NT5C2 NUCB2 PDE1A PDXK PHIP PIGV PLCB1 PMS2P5 PRDM8 PTPN12 PVRIG RGS19 RHOC RNASEH2C RNF34 RP11-296I10.6 RP11-436D10.3 RP11-538P18.2 RP11-588K22.2 RP11-613D13.5 RP11-810M2.2 RP4-635E18.7 RP4-671G15.2 RP5-1115A15.1 RPP25 RYK SENP1 SENP3 SH2B3 SIK2 SLC2A4 SLC35F6 SLC4A7 SOX6 SPATA33 STAG3L1 SWAP70 TBC1D19 TDRD1 TEAD2 TEX15 TH1L TMEM133 TMEM170A TNKS1BP1 TNNI2 TNNT3 TPD52L2 TSPY26P TUBB1 UBL7 UFL1 ULK3 WDR66 WNT2B YEATS4 ZBTB46 ZC3HC1 ZNF318 ZNF652 ZNF831 ZNRF3
Hypothyroidism (self reported) 1.55 2 1 2.2 0.00 1.0e+00 RP5-1115A15.1 SH2B3
Respiratory disease 1.75 8 4 8.9 0.74 3.5e-02 CHP1 HDAC7 HEXIM1 PDLIM4 RP5-1115A15.1 RUVBL1 SIK2 ZNF652
Type 2 Diabetes (T2D) (2018) 1.79 7 1 2.2 0.97 2.9e-04 ACE DBR1 FAM57B NDUFAF6 PMS2P5 SH2B3 ZBTB46
Lung FEV1/FVC ratio 1.99 27 16 35.6 -0.31 1.0e-01 ABO ATG7 ATP2B1 C1GALT1 C22orf31 CACNB2 CENPW CEP41 CTB-31O20.6 CYB5D1 GOPC HDAC7 HOXC8 KB-1107E3.1 NRBF2 PDLIM4 PVRIG RP11-436D10.3 RP11-810M2.2 RP5-1115A15.1 RUVBL1 STK32C TMEM133 TMEM170A TSPY26P WNT3 ZNF652
Lung FVC 1.51 17 10 22.2 0.00 9.9e-01 C1GALT1 CHP1 DBR1 DCAF16 HOXA10 HOXC8 KAT8 MAP2K5 NAT15 NCOA1 NRBF2 PDLIM4 RP11-538P18.2 RP11-613D13.5 SH2B3 WNT3 ZBTB46
Neuroticism 1.15 5 2 4.4 -0.49 4.1e-01 FURIN MAP2K5 NT5C2 RP5-1115A15.1 WNT3
Chronotype (morning person) 1.06 3 0 0.0 0.00 1.0e+00 RP11-810M2.2 RP4-671G15.2 RP5-1115A15.1
Hair Pigment 7.20 21 12 26.7 0.35 7.6e-02 ACP2 ATP2B1 C20orf160 C22orf31 C4orf22 CHMP1A DBR1 DEF8 DPEP1 FES HOXB9 PIGV RNASEH2C RP5-1115A15.1 SH2B3 SOX6 SPATA33 TSPY26P WNT3 ZNF831 ZNRF3
Tanning 8.17 9 7 15.6 -0.65 1.6e-02 CHMP1A DEF8 DPEP1 NRBF2 RP11-436D10.3 SH2B3 SPATA33 TSPY26P UBL7
Hand grip strength (left) 1.56 8 2 4.4 -0.55 1.6e-01 CHMP1A DCAF16 FAM57B FES HEXIM1 MGRN1 PDLIM4 WNT2B
Number of treatments/medications taken 3.95 14 6 13.3 0.94 7.0e-07 AC091133.1 ACE CHP1 CISD2 DCAF16 FAM108C1 FES SH2B3 STK32C TMEM133 TNKS1BP1 ZNF652 ZNF831 ZNRF3
Sensitivity / hurt feelings 1.36 4 3 6.7 -0.64 2.4e-01 AC091133.1 FES FURIN WNT3
Frequency of depressed mood in last 2 weeks 1.23 1 0 0.0 0.00 1.0e+00 RP5-1115A15.1
Hearing difficulty/problems: Yes 1.12 1 1 2.2 0.00 1.0e+00 ZNF318
Relative age of first facial hair 1.35 5 3 6.7 -0.74 1.5e-01 ATG7 C4orf22 HEXIM1 NRBF2 WNT3
Systolic blood pressure, automated reading 9.69 94 60 133.3 0.98 4.6e-69 AC006111.1 ACP2 ADRB1 AGT ATG7 ATP2B1 BICC1 C22orf31 C4orf22 CACNB2 CERS5 CHP1 CLCN6 CMIP COX5A CSK CTB-31O20.6 CWF19L2 DCAF16 FAM108C1 FAM57B FCF1P2 FES FURIN GLTP GOPC GTF2B HAUS8 HDAC7 HEXIM1 HOXA10 HOXB9 HOXC8 IPO11 KLF16 LFNG LIME1 LOC338758 LSP1 MED21 MGRN1 MPI MSRA MTHFR MYO9B NAT15 NCOA1 NEIL2 NOC3L NPPA-AS1 NPR3 NRBF2 NSUN6 NT5C2 NUCB2 PHIP PIGV PMS2P5 PRKD3 RGS19 RHOC RNASEH2C RP11-296I10.6 RP11-436D10.3 RP11-538P18.2 RP11-588K22.2 RP4-635E18.7 RP4-671G15.2 RP5-1115A15.1 RPP25 SENP3 SH2B3 SLC2A4 SLC4A7 SOX6 SRR STAG3L1 SWAP70 TBC1D19 TH1L TMEM133 TMEM170A TNNI2 TNNT3 TPD52L2 UBL7 UFL1 ULK3 WNT2B WNT3 ZBTB46 ZNF318 ZNF831 ZNRF3
Angina 2.48 3 3 6.7 0.98 2.1e-02 FES FURIN ZNF652
Medication: Metformin 1.63 3 0 0.0 0.00 1.0e+00 CISD2 DBR1 PMS2P5
Diabetes (father) 1.15 1 0 0.0 0.00 1.0e+00 AC091133.1
Pack years adult smoking proportion 1.26 1 0 0.0 0.00 1.0e+00 PMS2P5
Impedance of leg (right) 2.09 39 18 40.0 -0.06 7.2e-01 ABCF3 AC091133.1 ATG7 CEP41 CERS5 CTB-31O20.6 FAM108C1 FAM57B FES FURIN HAUS8 HEXIM1 HOXC8 JPH2 KAT8 KCNK3 KLF16 MAP2K5 MSRA MYO9B NEIL2 NELFCD NOC3L NT5C2 NUCB2 PMS2P5 PRKD3 RP11-296I10.6 RYK SENP1 SENP3 SLC35F6 SRR STAG3L1 SWAP70 TH1L TMEM133 WDR66 ZNF652
Leg fat-free mass (left) 1.77 28 14 31.1 0.26 1.8e-01 ABCF3 C10orf118 CENPW CTB-31O20.6 DCAF16 FAM108C1 FAM57B FES FURIN HEXIM1 KAT8 KCNK3 KLF16 MAP2K5 MSRA NEIL2 NPR3 NT5C2 PDE1A PDLIM4 RP11-436D10.3 RP11-613D13.5 SLC35F6 SRR STAG3L1 TDRD1 TEAD2 WDR66
Trunk fat percentage 2.03 27 13 28.9 0.60 1.1e-03 ABO AC091133.1 CHP1 COX5A CTB-31O20.6 DBR1 FAM108C1 FAM57B HOXA10 HOXC8 KAT8 KCNK3 KDM2B MAP2K5 MYO9B NOC3L RNF34 RP11-296I10.6 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 SENP3 SRR STAG3L1 STK32C TEX15 WNT3
Hand grip strength (right) 1.63 8 3 6.7 -0.78 2.3e-02 ABO DCAF16 HEXIM1 JARID2 PDLIM4 RHOC RP4-671G15.2 WNT2B
Townsend deprivation index at recruitment 1.19 2 0 0.0 0.00 1.0e+00 KLF16 MAP2K5
Current tobacco smoking 1.51 1 0 0.0 0.00 1.0e+00 MSRA
Maternal smoking around birth 1.22 1 0 0.0 0.00 1.0e+00 C20orf160
Fed-up feelings 1.22 2 1 2.2 0.00 1.0e+00 SH2B3 TEX15
Relative age voice broke 1.09 2 0 0.0 0.00 1.0e+00 RP11-613D13.5 WNT3
Taking other prescription medications 2.06 5 2 4.4 0.99 4.9e-04 CHP1 CISD2 PMS2P5 SH2B3 ZNF652
Age when periods started (menarche) 1.73 9 4 8.9 -0.55 1.2e-01 CTB-31O20.6 FAM57B KLF16 LSP1 MAP2K5 PMS2P5 RP11-613D13.5 STAG3L1 TNNI2
Heel bone mineral density (BMD) T-score, automated (left) 1.59 9 3 6.7 -0.11 7.8e-01 ACP2 CMIP CYB5D1 MSRA NEIL2 RNASEH2C RP5-1115A15.1 WNT2B ZNRF3
Hayfever, allergic rhinitis or eczema 1.94 6 5 11.1 0.37 4.7e-01 CHP1 MPI PDLIM4 RP5-1115A15.1 SIK2 ZNF652
Multivitamins +/- minerals 1.17 1 0 0.0 0.00 1.0e+00 NRBF2
Supplements: Glucosamine 1.72 2 1 2.2 0.00 1.0e+00 CSK NRBF2
Medication: Atenolol 5.38 7 2 4.4 0.99 3.5e-06 CLCN6 FES FURIN PRKD3 RHOC SH2B3 TMEM133
Medication: Levothyroxine sodium 1.55 2 1 2.2 0.00 1.0e+00 MSRA SH2B3
Sitting height 1.36 25 13 28.9 -0.11 6.1e-01 AC091133.1 ADRB1 C10orf118 C20orf160 CENPW CERS5 CHMP1A CHP1 DCAF16 FCN3 GOPC GTF2B HEXIM1 JARID2 NPR3 PDLIM4 RP11-436D10.3 RP11-538P18.2 SLC35F6 SLC4A7 WDR66 WNT3 ZNF652 ZNF831 ZNRF3
High blood pressure (mother) 5.88 14 4 8.9 0.98 1.1e-10 AGT CENPW CHMP1A CLCN6 FES FURIN HOXA10 HOXC8 LSP1 NT5C2 PIGV SENP1 SLC4A7 ZNF831
Body mass index (BMI) 2.19 27 19 42.2 0.76 2.4e-06 AC091133.1 CEP41 COX5A CTB-31O20.6 EXOC4 FAM108C1 FAM57B KAT8 KCNK3 KDM2B KLF16 MAP2K5 MSRA NEIL2 NRBF2 NT5C2 PMS2P5 RP11-296I10.6 RP11-613D13.5 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEAD2 TEX15
Impedance of leg (left) 2.08 34 20 44.4 -0.15 3.9e-01 ABCF3 AC091133.1 ATG7 CEP41 CERS5 CTB-31O20.6 FAM108C1 FAM57B FES FURIN HAUS8 HEXIM1 HOXC8 JPH2 KAT8 KCNK3 KLF16 MAP2K5 MSRA MYO9B NEIL2 NELFCD NOC3L NT5C2 NUCB2 PMS2P5 PRKD3 RP11-296I10.6 SLC35F6 SRR STAG3L1 SWAP70 TMEM133 ZNF652
Leg predicted mass (left) 1.77 30 14 31.1 0.23 2.3e-01 ABCF3 C10orf118 CENPW CTB-31O20.6 DCAF16 FAM108C1 FAM57B FES FURIN HAUS8 HEXIM1 KAT8 KCNK3 KLF16 MAP2K5 MSRA MYO9B NEIL2 NPR3 NT5C2 PDE1A PDLIM4 RP11-436D10.3 RP11-613D13.5 SLC35F6 SRR STAG3L1 TDRD1 TEAD2 WDR66
Trunk fat mass 1.94 25 10 22.2 0.52 7.1e-03 COX5A CTB-31O20.6 DBR1 FAM108C1 FAM57B HOXA10 HOXC8 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 MAP2K5 NT5C2 RP11-296I10.6 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEAD2 TEX15
Waist circumference 2.22 26 13 28.9 0.60 1.3e-03 CMIP COX5A CTB-31O20.6 FAM108C1 FAM57B HOXC8 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 MAP2K5 MPI NRBF2 PHIP RP11-296I10.6 RP11-613D13.5 RP11-810M2.2 RPP25 SRR STAG3L1 STK32C TDRD1 TEAD2 TEX15 UBL7
Number of incorrect matches in round 1.37 4 1 2.2 -1.00 4.5e-05 FAM57B FES FURIN KAT8
Past tobacco smoking 1.35 2 1 2.2 0.00 1.0e+00 MAP2K5 SH2B3
Alcohol usually taken with meals 1.31 1 0 0.0 0.00 1.0e+00 FES
Nervous feelings 1.29 3 1 2.2 0.00 1.0e+00 KAT8 MSRA NT5C2
Frequency of tenseness / restlessness in last 2 weeks 1.08 1 0 0.0 0.00 1.0e+00 NT5C2
Hearing difficulty/problems with background noise 1.48 4 1 2.2 -1.00 5.7e-05 CSK MPI UBL7 ZNF318
Hair/balding pattern: Pattern 2 1.43 2 1 2.2 0.00 1.0e+00 C4orf22 PRDM8
Had menopause 1.01 1 0 0.0 0.00 1.0e+00 CHP1
Forced vital capacity (FVC) 1.61 13 6 13.3 -0.41 1.6e-01 ACP2 CENPW CHMP1A DCAF16 HOXC8 KAT8 NCOA1 RHOC RP11-538P18.2 RP4-671G15.2 WDR66 WNT2B WNT3
Heel bone mineral density (BMD) T-score, automated (right) 1.59 9 4 8.9 -0.04 9.2e-01 ACP2 CYB5D1 DCAF16 MSRA NEIL2 RNASEH2C RP5-1115A15.1 WNT2B ZNRF3
Qualifications: None of the above 1.26 2 1 2.2 0.00 1.0e+00 NRBF2 PHIP
Mouth/teeth dental problems 1.29 1 0 0.0 0.00 1.0e+00 PMS2P5
Heart attack 2.26 3 1 2.2 0.00 1.0e+00 FES ZC3HC1 ZNF652
Allergy 2.17 10 6 13.3 -0.24 5.0e-01 ABO CHP1 FES HDAC7 HEXIM1 LIME1 PDLIM4 RP5-1115A15.1 SIK2 ZNF652
Diabetes (self-reported) 1.83 2 1 2.2 0.00 1.0e+00 PMS2P5 ZBTB46
Medication: Ramipril 4.74 8 2 4.4 0.98 3.9e-06 CISD2 CMIP CSK FES GOPC LSP1 TMEM133 ZC3HC1
Medication: Simvastatin 3.27 5 1 2.2 0.42 4.0e-01 ABO FES PIGV RNASEH2C ZNF831
Fluid intelligence score 1.05 1 1 2.2 0.00 1.0e+00 DCAF16
Illnesses of siblings 3.44 6 1 2.2 -0.99 8.0e-06 FES KAT8 NRBF2 SH2B3 TMEM133 YEATS4
Neuroticism score 1.15 4 3 6.7 -0.99 1.2e-02 MSRA NEIL2 RP5-1115A15.1 WNT3
Weight 1.88 26 14 31.1 0.47 1.5e-02 C10orf118 CTB-31O20.6 DCAF16 FAM108C1 FAM57B KAT8 KB-1107E3.1 KCNK3 KLF16 MAP2K5 MSRA NEIL2 NT5C2 PDLIM4 RP11-296I10.6 RP11-436D10.3 RP11-613D13.5 RP11-810M2.2 RPP25 SH2B3 SRR STAG3L1 STK32C TDRD1 TEAD2 WDR66
Impedance of arm (right) 2.02 32 13 28.9 -0.50 2.3e-03 ABO ARID3B C22orf31 CEP41 CERS5 CISD2 CMIP CTB-31O20.6 FAM57B HAUS8 HEXIM1 HOXA10 HOXC8 KAT8 KLF16 LIME1 LSP1 MAP2K5 MSRA MYO9B NEIL2 NOC3L NRBF2 NUCB2 PDE1A RYK SENP1 SENP3 SLC4A7 STAG3L1 TSPY26P ZNF652
Arm fat percentage (right) 2.20 32 17 37.8 0.61 2.1e-04 ABO AC091133.1 CHP1 COX5A CTB-31O20.6 DCAF16 FAM108C1 FAM57B FBF1 HOXA10 HOXC8 KAT8 KCNK3 KDM2B KLF16 MAP2K5 MSRA NT5C2 PMS2P5 RNF34 RP11-296I10.6 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 SENP3 SLC2A4 SRR STAG3L1 STK32C TDRD1 TEAD2 TEX15
Trunk fat-free mass 1.82 28 15 33.3 0.04 8.3e-01 ABO C10orf118 CENPW CHMP1A DCAF16 FAM108C1 FAM57B HAUS8 HEXIM1 JARID2 KAT8 KCNK3 KLF16 LIME1 MYO9B NCOA1 NPR3 NT5C2 PDE1A PDLIM4 RP11-436D10.3 SENP3 SH2B3 SLC35F6 SLC4A7 TEAD2 TMEM133 WDR66
Hip circumference 1.82 25 12 26.7 0.47 1.8e-02 C10orf118 CLCN6 CTB-31O20.6 DCAF16 FAM108C1 FAM57B KAT8 KB-1107E3.1 KCNK3 KLF16 MAP2K5 MSRA NPPA-AS1 NT5C2 PHIP PMS2P5 RP11-296I10.6 RP11-436D10.3 RP11-613D13.5 RP11-810M2.2 SH2B3 SRR STAG3L1 STK32C WDR66
Alcohol intake versus 10 years previously 1.06 1 0 0.0 0.00 1.0e+00 FAM57B
Father's age at death 2.30 4 2 4.4 -0.71 2.9e-01 ABO FES MPI SH2B3
Worrier / anxious feelings 1.41 4 1 2.2 -0.60 4.0e-01 KAT8 MSRA NEIL2 NT5C2
Frequency of tiredness / lethargy in last 2 weeks 1.24 2 0 0.0 0.00 1.0e+00 AC091133.1 RP5-1115A15.1
Hair/balding pattern: Pattern 3 1.74 4 2 4.4 0.71 2.9e-01 C4orf22 HEXIM1 PRDM8 WNT3
Forced expiratory volume in 1-second (FEV1) 1.71 16 3 6.7 -0.22 4.1e-01 ABO CHMP1A DCAF16 GOPC KAT8 MSRA NCOA1 NRBF2 PDLIM4 RHOC RP11-538P18.2 RUVBL1 TMEM133 TSPY26P UBE2E3 WNT3
Qualifications: A levels/AS levels or equivalent 1.24 2 0 0.0 0.00 1.0e+00 DCAF16 STAG3L1
Mouth/teeth dental problems: Dentures 1.11 1 0 0.0 0.00 1.0e+00 HOXB9
Asthma 1.94 6 4 8.9 0.67 1.4e-01 HDAC7 PDLIM4 RP5-1115A15.1 RUVBL1 SIK2 ZNF652
Medication: Cholesterol lowering 3.31 8 2 4.4 0.77 1.6e-02 ABO CHP1 FES PIGV PVRIG RNASEH2C TMEM133 ZNF831
Depression (self-reported) 1.01 1 0 0.0 0.00 1.0e+00 RP5-1115A15.1
Illnesses of mother 3.55 1 1 2.2 0.00 1.0e+00 FES
Forced expiratory volume in 1-second (FEV1), Best measure 1.67 11 5 11.1 -0.28 4.0e-01 ABO DCAF16 KAT8 MSRA NCOA1 NRBF2 PDLIM4 RP11-538P18.2 RUVBL1 TMEM133 WNT3
Impedance of arm (left) 2.05 31 15 33.3 -0.38 2.5e-02 ABO ARID3B C22orf31 CERS5 CISD2 CMIP FAM108C1 FAM57B HAUS8 HEXIM1 HOXA10 HOXC8 KAT8 LIME1 LSP1 MAP2K5 MSRA MYO9B NEIL2 NOC3L NRBF2 PDE1A PRKD3 RYK SENP1 SENP3 SH2B3 SLC4A7 STAG3L1 TSPY26P ZNF652
Arm fat mass (right) 2.08 26 13 28.9 0.68 1.5e-04 AC091133.1 COX5A CTB-31O20.6 FAM108C1 FAM57B HOXA10 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 MAP2K5 MSRA NT5C2 PMS2P5 RP11-296I10.6 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEAD2 TEX15
Trunk predicted mass 1.82 27 14 31.1 0.05 7.9e-01 ABO C10orf118 CENPW CHMP1A DCAF16 FAM108C1 FAM57B HAUS8 HEXIM1 JARID2 KAT8 KCNK3 KLF16 LIME1 MYO9B NCOA1 NPR3 NT5C2 PDE1A PDLIM4 RP11-436D10.3 SENP3 SH2B3 SLC35F6 SLC4A7 TEAD2 WDR66
Standing height 1.67 41 26 57.8 -0.23 1.5e-01 AC091133.1 ACP2 ADRB1 C10orf118 CENPW CERS5 CHMP1A CHP1 DCAF16 FAM57B GOPC GTF2B HEXIM1 LSP1 MGRN1 MSRA NCOA1 NPR3 NRBF2 NUCB2 PDE1A PDLIM4 PIGV PTPN12 RHOC RP11-436D10.3 RP11-538P18.2 RP11-810M2.2 RP4-635E18.7 RP4-671G15.2 RP5-1115A15.1 RYK SH2B3 SLC35F6 SLC4A7 TMEM170A WDR66 WNT2B ZNF318 ZNF652 ZNF831
Tense / 'highly strung' 1.11 3 0 0.0 0.00 1.0e+00 KAT8 NT5C2 RP5-1115A15.1
Hair/balding pattern: Pattern 4 2.17 10 6 13.3 0.41 2.3e-01 C4orf22 CENPW CERS5 HEXIM1 KAT2B PRDM8 RP5-1115A15.1 SPATA33 SRR WNT3
Birth weight of first child 2.77 13 4 8.9 -0.98 3.5e-11 CLCN6 COX5A CSK DCAF16 FES FURIN GTF2B MTHFR NPPA-AS1 RPP25 SH2B3 STAG3L1 TMEM170A
Peak expiratory flow (PEF) 1.66 7 3 6.7 -0.21 6.5e-01 ABO C1GALT1 CHMP1A DCAF16 MSRA TMEM170A WNT3
Blood clot in the leg (DVT) 2.72 1 1 2.2 0.00 1.0e+00 ABO
Medication: Paracetamol 1.50 1 0 0.0 0.00 1.0e+00 UFL1
Headache pain in last month 1.48 4 1 2.2 -0.24 7.6e-01 MAP2K5 TMEM170A UFL1 WNT3
Medication for cholesterol, blood pressure or diabetes 7.27 36 12 26.7 -0.98 5.7e-30 ACE ATP2B1 C1GALT1 C4orf22 CHP1 CISD2 CLCN6 CSK FAM108C1 FCF1P2 FES FURIN JARID2 LFNG LOC338758 LSP1 MTHFR NGF OSGIN2 PDXK PLCB1 PVRIG RGS19 RHOC RP11-296I10.6 RP11-588K22.2 SENP1 SH2B3 SIK2 SLC4A7 TH1L TMEM133 TSPY26P ZBTB46 ZNF652 ZNF831
Gout (self-reported) 1.38 1 0 0.0 0.00 1.0e+00 SH2B3
Hypothyroidism/myxoedema (self-reported) 1.47 3 1 2.2 0.00 1.0e+00 MSRA RP5-1115A15.1 SH2B3
Medication: Amlodipine 6.72 21 10 22.2 0.97 1.4e-15 CLCN6 FAM108C1 FES KCNK3 KDM2B LSP1 MTHFR NPPA-AS1 OSGIN2 RHOC RNF34 RP4-635E18.7 RP4-671G15.2 SENP1 SENP3 SLC35F6 TMEM133 TNNI2 TNNT3 WNT2B ZNF318
Medication: Ventolin 100micrograms inhaler 1.49 1 0 0.0 0.00 1.0e+00 ZNF652
Birth weight 2.23 10 8 17.8 -0.55 7.7e-02 ADRB1 DCAF16 FES FURIN SH2B3 SIK2 SLC2A4 SRR TNNT3 ZNRF3
High blood pressure (siblings) 4.74 9 4 8.9 0.98 4.9e-07 ACP2 CLCN6 FES KAT8 LSP1 NRBF2 RHOC SH2B3 TMEM133
Forced vital capacity (FVC), Best measure 1.49 10 5 11.1 -0.30 4.0e-01 ACP2 CENPW CHMP1A DCAF16 KAT8 NCOA1 RHOC RP11-538P18.2 RP11-613D13.5 WNT3
Body fat percentage 2.11 29 13 28.9 0.59 8.5e-04 ABO AC091133.1 CHP1 COX5A CTB-31O20.6 DBR1 DCAF16 FAM108C1 FAM57B HOXA10 HOXC8 KAT8 KCNK3 KDM2B MAP2K5 MYO9B NOC3L PMS2P5 RNF34 RP11-296I10.6 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 SENP3 SRR STAG3L1 STK32C TEX15
Leg fat percentage (right) 2.12 23 12 26.7 0.82 1.8e-06 CHP1 COX5A CTB-31O20.6 DCAF16 FAM108C1 FAM57B GTF2B KAT8 KCNK3 KDM2B MAP2K5 MSRA NOC3L NRBF2 RP11-296I10.6 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 SLC2A4 STAG3L1 STK32C TEX15
Arm fat-free mass (right) 1.80 25 12 26.7 0.09 6.6e-01 ABO C10orf118 CENPW CHMP1A DCAF16 FAM108C1 FAM57B HAUS8 HEXIM1 KAT8 KCNK3 KLF16 LIME1 MAP2K5 MYO9B NEIL2 NPR3 PDE1A PDLIM4 RP11-436D10.3 SENP3 SH2B3 SLC35F6 STAG3L1 WDR66
Comparative body size at age 10 1.66 9 6 13.3 0.42 2.6e-01 ATG7 CERS5 FAM57B FCF1P2 KAT8 MAP2K5 MSRA SRR ZNF652
Worry too long after embarrassment 1.25 1 0 0.0 0.00 1.0e+00 MSRA
Seen a psychiatrist for nerves, anxiety, tension or depression 1.35 1 0 0.0 0.00 1.0e+00 ADRB1
Wheeze or whistling in the chest in last year 1.71 2 0 0.0 0.00 1.0e+00 SIK2 ZNF652
Age at first live birth 1.29 1 0 0.0 0.00 1.0e+00 DCAF16
Qualifications: College or University degree 1.05 6 2 4.4 -0.71 1.1e-01 DCAF16 FAM57B GTF2B STAG3L1 TEX15 WNT3
Medication for pain relief, constipation, heartburn 1.81 5 2 4.4 -0.98 4.1e-03 ACE C20orf160 FAM108C1 STK32C UFL1
Neck or shoulder pain in last month 1.35 1 0 0.0 0.00 1.0e+00 RP5-1115A15.1
Medication: Blood pressure 10.09 69 30 66.7 0.99 5.1e-63 AC091133.1 ACE ACP2 ADRB1 ATP2B1 BICC1 C1GALT1 C20orf160 C4orf22 CEP41 CHMP1A CISD2 CLCN6 CMIP CSK CWF19L2 CYB5D1 DCAF16 FAM108C1 FAM57B FCF1P2 FES FURIN HOXA10 JARID2 KDM2B KLF16 LDB3 LFNG LOC338758 LSP1 MSRA MTHFR NELFCD NGF NOC3L NPPA-AS1 OSGIN2 PDXK PLCB1 PRDM8 PVRIG RHOC RNF34 RP11-810M2.2 RP4-635E18.7 RP4-671G15.2 SENP1 SENP3 SH2B3 SIK2 SLC2A4 SLC4A7 SOX6 SPATA33 STAG3L1 TH1L TMEM133 TNNI2 TNNT3 TSPY26P ULK3 WDR66 WNT2B ZBTB46 ZC3HC1 ZNF318 ZNF652 ZNF831
Angina (self-reported) 2.50 3 1 2.2 0.99 1.3e-02 FES FURIN ZNF652
Migraine (self-reported) 1.23 1 1 2.2 0.00 1.0e+00 UFL1
Medication: Allopurinol 1.52 3 0 0.0 0.00 1.0e+00 CYB5D1 SH2B3 WDR66
Medication: Seretide 50 evohaler 1.33 2 0 0.0 0.00 1.0e+00 PDLIM4 ZNF652
Mean time to correctly identify matches 1.06 2 1 2.2 0.00 1.0e+00 RP11-810M2.2 SH2B3
Whole body fat mass 1.98 27 14 31.1 0.63 4.3e-04 AC091133.1 COX5A CTB-31O20.6 DBR1 FAM108C1 FAM57B HOXA10 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 MAP2K5 MSRA NT5C2 PMS2P5 RP11-296I10.6 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEAD2 TEX15
Leg fat mass (right) 2.04 23 12 26.7 0.88 2.9e-08 AC091133.1 CTB-31O20.6 FAM108C1 FAM57B KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 MAP2K5 MSRA NRBF2 PMS2P5 RP11-296I10.6 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 STAG3L1 STK32C TEAD2 TEX15 TSPY26P
Arm predicted mass (right) 1.80 24 12 26.7 0.17 4.3e-01 ABO C10orf118 CENPW CMIP DCAF16 FAM108C1 FAM57B HEXIM1 KAT8 KCNK3 KLF16 LIME1 MAP2K5 MYO9B NEIL2 PDE1A PDLIM4 RP11-436D10.3 SENP3 SH2B3 SLC35F6 STAG3L1 TSPY26P WDR66
Pulse rate, automated reading 1.16 5 1 2.2 0.06 9.2e-01 ABO ACP2 C4orf22 PVRIG SIK2
Alcohol intake frequency. 1.44 6 2 4.4 0.99 2.5e-04 ARID3B FAM57B KAT8 PMS2P5 TEX15 ZNF318
Comparative height size at age 10 1.54 20 11 24.4 -0.11 6.6e-01 CENPW CHMP1A DCAF16 FAM108C1 FAM57B FES GTF2B NAT15 NCOA1 NPR3 NUCB2 PDLIM4 PIGV RP11-613D13.5 RP11-810M2.2 RP4-635E18.7 RP5-1115A15.1 RYK SH2B3 WDR66
Number of full sisters 1.33 1 0 0.0 0.00 1.0e+00 NRBF2
Suffer from 'nerves' 1.15 1 0 0.0 0.00 1.0e+00 RP5-1115A15.1
Overall health rating 2.05 10 3 6.7 0.98 4.6e-07 AC091133.1 C1GALT1 HEXIM1 KAT8 MSRA PMS2P5 RNASEH2C TEX15 TSPY26P ZNF652
Chest pain or discomfort 1.34 1 0 0.0 0.00 1.0e+00 KB-1107E3.1
Had major operations 1.21 1 0 0.0 0.00 1.0e+00 ZNF652
Medication: Aspirin 3.52 4 1 2.2 0.98 4.6e-03 AC091133.1 FES GOPC SIK2
Knee pain experienced in last month 1.46 1 0 0.0 0.00 1.0e+00 ARID3B
Hypertension (Self-reported) 14.79 160 140 311.1 1.00 1.2e-241 ABCF3 ABO AC006111.1 AC091133.1 ACE ACP2 ADRB1 AGT AKR1B15 ALOX12 ARID3B ATG7 ATP2B1 BICC1 C10orf118 C1GALT1 C20orf160 C22orf31 C4orf22 CACNB2 CAND1 CENPW CEP41 CERS5 CHMP1A CHP1 CISD2 CLCN6 CMIP COX5A CSK CTB-31O20.6 CWF19L2 CYB5D1 DBR1 DCAF16 DEF8 DPEP1 ENPEP EXOC4 FAM108C1 FAM57B FBF1 FCF1P2 FCN3 FES FURIN GLTP GOPC GTF2B HAUS8 HDAC7 HEXIM1 HOXA10 HOXB9 HOXC8 HRCT1 IPO11 JARID2 JPH2 KANK1 KAT2B KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 LDB3 LFNG LIME1 LOC338758 LSP1 MAP2K5 MED21 MGRN1 MPI MSRA MTHFR MYO9B NAT15 NCOA1 NDUFAF6 NEIL2 NELFCD NGF NOC3L NPPA-AS1 NPR3 NRBF2 NSUN6 NT5C2 NUCB2 OSGIN2 PDE1A PDLIM4 PDXK PHIP PIGV PLCB1 PMS2P5 PRDM8 PRKD3 PTPN12 PVRIG RGS19 RHOC RNASEH2C RNF34 RP11-296I10.6 RP11-436D10.3 RP11-538P18.2 RP11-588K22.2 RP11-613D13.5 RP11-810M2.2 RP4-635E18.7 RP4-671G15.2 RP5-1115A15.1 RPP25 RUVBL1 RYK SENP1 SENP3 SH2B3 SIK2 SLC2A4 SLC35F6 SLC4A7 SOX6 SPATA33 SRR STAG3L1 STK32C SWAP70 TBC1D19 TDRD1 TEAD2 TEX15 TH1L TMEM133 TMEM170A TNKS1BP1 TNNI2 TNNT3 TPD52L2 TSPY26P TUBB1 UBE2E3 UBL7 UFL1 ULK3 WDR66 WNT2B WNT3 YEATS4 ZBTB46 ZC3HC1 ZNF318 ZNF652 ZNF831 ZNRF3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.20 1 0 0.0 0.00 1.0e+00 KDM2B
Illnesses of father: Heart disease 2.16 3 1 2.2 0.73 2.7e-01 ABO FES RGS19
Smoking status: Previous 1.20 2 0 0.0 0.00 1.0e+00 MAP2K5 SH2B3
Forced expiratory volume in 1-second (FEV1), predicted 1.45 4 2 4.4 -0.95 5.0e-02 DCAF16 HEXIM1 MGRN1 PDLIM4
Whole body fat-free mass 1.80 25 14 31.1 0.05 8.0e-01 C10orf118 CENPW DCAF16 FAM108C1 FAM57B HAUS8 HEXIM1 KAT8 KCNK3 KLF16 MAP2K5 MYO9B NEIL2 NPR3 NT5C2 PDE1A PDLIM4 RP11-436D10.3 SENP3 SH2B3 SLC35F6 SLC4A7 STAG3L1 TEAD2 WDR66
Leg fat-free mass (right) 1.79 29 15 33.3 0.06 7.7e-01 ABCF3 C10orf118 CENPW DCAF16 FAM108C1 FAM57B FES FURIN HAUS8 HEXIM1 KAT8 KCNK3 KLF16 MAP2K5 MSRA MYO9B NEIL2 NPR3 NT5C2 PDE1A PDLIM4 RP11-436D10.3 SH2B3 SLC35F6 SRR STAG3L1 TDRD1 TMEM133 WDR66
Arm fat percentage (left) 2.17 29 18 40.0 0.53 2.9e-03 ABO AC091133.1 CHP1 COX5A CTB-31O20.6 DCAF16 FAM108C1 FAM57B FBF1 HOXA10 HOXC8 KAT8 KCNK3 KDM2B KLF16 MAP2K5 MSRA NT5C2 PMS2P5 RNF34 RP11-296I10.6 RP11-613D13.5 RP5-1115A15.1 RPP25 SENP3 SRR STAG3L1 STK32C TEX15
Average weekly red wine intake 1.45 2 0 0.0 0.00 1.0e+00 MPI NRBF2
Mood swings 1.21 3 0 0.0 0.00 1.0e+00 ACP2 OSGIN2 WNT3
Loneliness, isolation 1.20 1 0 0.0 0.00 1.0e+00 RP5-1115A15.1
Long-standing illness, disability or infirmity 1.81 3 0 0.0 0.00 1.0e+00 CHP1 PMS2P5 ZNF652
Ever had bowel cancer screening 1.20 1 0 0.0 0.00 1.0e+00 SIK2
Diabetes diagnosed by doctor 1.91 3 2 4.4 0.00 1.0e+00 DBR1 PMS2P5 ZBTB46
Mouth/teeth dental problems: Mouth ulcers 1.24 1 0 0.0 0.00 1.0e+00 OSGIN2
Medication for cholesterol 6.64 28 8 17.8 -0.97 3.5e-20 ACE ATG7 C4orf22 CENPW CISD2 CMIP DEF8 FES HAUS8 HOXA10 HOXC8 JARID2 KAT8 LIME1 LSP1 MGRN1 PIGV PLCB1 PRKD3 RHOC RP4-671G15.2 SENP1 SH2B3 TMEM133 WNT2B ZBTB46 ZNF831 ZNRF3
Back pain experienced in last month 1.60 1 0 0.0 0.00 1.0e+00 WDR66
Mineral and other dietary supplements 1.43 1 1 2.2 0.00 1.0e+00 NRBF2
Breast cancer (self-reported) 1.30 1 0 0.0 0.00 1.0e+00 SLC4A7
Asthma (self-reported) 1.93 7 4 8.9 0.51 2.4e-01 FBF1 HDAC7 PDLIM4 RP5-1115A15.1 RUVBL1 SIK2 ZNF652
Osteoarthritis (self-reported) 1.69 3 0 0.0 0.00 1.0e+00 CHMP1A COX5A RPP25
Medication: Aspirin 3.69 2 1 2.2 0.00 1.0e+00 FES SIK2
Medication: Gliclazide 1.38 1 0 0.0 0.00 1.0e+00 DBR1
Illnesses of father: None of the above (group 1) 2.65 2 1 2.2 0.00 1.0e+00 FES SH2B3
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.55 5 3 6.7 -0.20 7.5e-01 KAT8 NRBF2 RP11-538P18.2 TMEM170A WNT3
Whole body water mass 1.81 26 14 31.1 0.10 6.2e-01 C10orf118 CENPW DCAF16 FAM108C1 FAM57B HAUS8 HEXIM1 KAT8 KCNK3 KLF16 MAP2K5 MSRA MYO9B NEIL2 NPR3 NT5C2 PDE1A PDLIM4 RP11-436D10.3 SENP3 SH2B3 SLC35F6 SLC4A7 STAG3L1 TEAD2 WDR66
Leg predicted mass (right) 1.79 29 15 33.3 0.05 7.8e-01 ABCF3 C10orf118 CENPW DCAF16 FAM108C1 FAM57B FES FURIN HAUS8 HEXIM1 KAT8 KCNK3 KLF16 MAP2K5 MSRA MYO9B NEIL2 NPR3 NT5C2 PDE1A PDLIM4 RP11-436D10.3 SH2B3 SLC35F6 SRR STAG3L1 TDRD1 TMEM133 WDR66
Arm fat mass (left) 2.03 25 12 26.7 0.67 2.5e-04 AC091133.1 COX5A CTB-31O20.6 FAM108C1 FAM57B HOXA10 KAT8 KCNK3 KDM2B KLF16 MAP2K5 MSRA NT5C2 PMS2P5 RP11-296I10.6 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEAD2 TEX15
Number of self-reported non-cancer illnesses 4.22 15 5 11.1 0.98 5.9e-10 CISD2 CLCN6 CYB5D1 HAUS8 HDAC7 KDM2B MYO9B PDLIM4 PMS2P5 RUVBL1 SH2B3 ZNF318 ZNF652 ZNF831 ZNRF3
Miserableness 1.09 3 0 0.0 0.00 1.0e+00 ACP2 RP5-1115A15.1 WNT3
Guilty feelings 0.98 1 0 0.0 0.00 1.0e+00 NEIL2
Eye problems/disorders: Glaucoma 1.15 1 0 0.0 0.00 1.0e+00 TEX15
Medication: Blood pressure 11.45 89 45 100.0 0.99 6.7e-77 ACE ACP2 ADRB1 AGT AKR1B15 ARID3B ATG7 ATP2B1 C1GALT1 C4orf22 CACNB2 CENPW CERS5 CHMP1A CHP1 CISD2 CLCN6 CMIP COX5A CSK CWF19L2 CYB5D1 DBR1 DEF8 DPEP1 FAM108C1 FCF1P2 FES FURIN GTF2B HAUS8 HEXIM1 HOXA10 HOXC8 HRCT1 KAT8 KB-1107E3.1 KCNK3 KDM2B LFNG LIME1 LSP1 MGRN1 MPI MSRA MTHFR MYO9B NCOA1 NEIL2 NRBF2 NSUN6 NT5C2 PDLIM4 PDXK PIGV PLCB1 PRKD3 PTPN12 RGS19 RHOC RNASEH2C RNF34 RP11-436D10.3 RP11-588K22.2 RP11-810M2.2 RP4-635E18.7 RP4-671G15.2 RPP25 SENP3 SH2B3 SIK2 SLC35F6 SLC4A7 SPATA33 TBC1D19 TDRD1 TEX15 TMEM133 TNKS1BP1 TNNI2 TNNT3 TPD52L2 UBL7 WNT2B WNT3 ZBTB46 ZNF318 ZNF831 ZNRF3
Supplements: Fish oil (including cod liver oil) 1.16 1 0 0.0 0.00 1.0e+00 HEXIM1
High cholesterol (Self-reported) 2.61 6 3 6.7 0.17 7.4e-01 ABO DCAF16 FBF1 PIGV RGS19 TMEM133
Medication: Bendroflumethiazide 7.94 35 13 28.9 0.97 1.2e-25 ABCF3 ACP2 ADRB1 AGT ATP2B1 CACNB2 CHMP1A CLCN6 CSK FAM108C1 FAM57B FES HOXA10 JPH2 KAT8 LSP1 MGRN1 MYO9B NEIL2 NRBF2 PDLIM4 PIGV PLCB1 RHOC RP11-436D10.3 RP4-671G15.2 SENP3 SH2B3 SLC35F6 SLC4A7 TEX15 TMEM133 TNNI2 WNT2B ZNF831
Medication: Paracetamol 1.51 1 0 0.0 0.00 1.0e+00 UFL1
Medication: Lisinopril 4.69 6 0 0.0 0.98 1.2e-05 ACP2 CSK FCF1P2 LSP1 NRBF2 ZNF831
Medication: Atorvastatin 1.68 1 0 0.0 0.00 1.0e+00 ABO
Illnesses of father: High blood pressure 4.77 8 1 2.2 0.98 7.2e-08 ACE ACP2 C4orf22 CHMP1A FES NCOA1 PLCB1 SPATA33
Ever smoked 1.26 3 0 0.0 0.00 1.0e+00 MAP2K5 SH2B3 SRR
Basal metabolic rate 1.79 24 16 35.6 0.21 3.2e-01 C10orf118 CENPW DCAF16 FAM108C1 FAM57B HEXIM1 KAT8 KCNK3 KLF16 MAP2K5 MSRA NEIL2 NPR3 NT5C2 PDE1A PDLIM4 RP11-436D10.3 RP11-613D13.5 SH2B3 SLC35F6 STAG3L1 TDRD1 TEAD2 WDR66
Leg fat percentage (left) 2.13 24 10 22.2 0.82 1.1e-06 CHP1 COX5A CTB-31O20.6 DCAF16 FAM108C1 FAM57B GTF2B KAT8 KCNK3 KDM2B MAP2K5 MSRA NOC3L NRBF2 PMS2P5 RP11-296I10.6 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 SLC2A4 STAG3L1 STK32C TEX15
Arm fat-free mass (left) 1.81 28 12 26.7 0.23 2.3e-01 ABO C10orf118 CENPW CMIP DCAF16 FAM108C1 FAM57B HEXIM1 KAT8 KCNK3 KLF16 LIME1 MAP2K5 MSRA NEIL2 NPR3 NT5C2 PDE1A PDLIM4 RP11-613D13.5 RP11-810M2.2 SENP3 SH2B3 SLC35F6 STAG3L1 TEAD2 TSPY26P WDR66
Irritability 1.02 2 2 4.4 0.00 1.0e+00 MSRA NEIL2
Risk taking 1.21 2 0 0.0 0.00 1.0e+00 KCNK3 STK32C
Diastolic blood pressure, automated reading 9.24 93 60 133.3 0.97 1.8e-67 ABO AC006111.1 AC091133.1 ACE ACP2 ADRB1 AGT ATP2B1 C10orf118 C1GALT1 C20orf160 C22orf31 C4orf22 CACNB2 CENPW CEP41 CERS5 CHP1 CLCN6 CMIP COX5A CSK CTB-31O20.6 CWF19L2 CYB5D1 DCAF16 DPEP1 ENPEP FAM108C1 FCF1P2 FES FURIN GLTP HAUS8 HDAC7 HEXIM1 HOXA10 HRCT1 IPO11 KAT8 LFNG LIME1 LOC338758 LSP1 MAP2K5 MED21 MPI MSRA MTHFR MYO9B NCOA1 NDUFAF6 NEIL2 NELFCD NOC3L NPPA-AS1 NRBF2 NSUN6 NT5C2 PDE1A PDLIM4 PHIP PIGV PMS2P5 PVRIG RGS19 RHOC RNASEH2C RP11-296I10.6 RP11-436D10.3 RP11-538P18.2 RP4-671G15.2 RP5-1115A15.1 RPP25 RYK SENP3 SH2B3 SLC2A4 SRR STAG3L1 SWAP70 TBC1D19 TH1L TMEM133 TNNI2 TSPY26P TUBB1 UBL7 ULK3 WNT2B ZC3HC1 ZNF652 ZNF831
Myopia 1.23 2 0 0.0 0.00 1.0e+00 RP4-671G15.2 WNT2B
Vascular/heart problems diagnosed by doctor 14.25 160 115 255.6 -1.00 2.5e-200 ABCF3 ABO AC006111.1 AC091133.1 ACE ACP2 ADRB1 AGT AKR1B15 ALOX12 ARID3B ATG7 ATP2B1 BICC1 C10orf118 C1GALT1 C20orf160 C22orf31 C4orf22 CACNB2 CAND1 CENPW CEP41 CERS5 CHMP1A CHP1 CISD2 CLCN6 CMIP COX5A CSK CTB-31O20.6 CWF19L2 CYB5D1 DBR1 DCAF16 DEF8 DPEP1 ENPEP EXOC4 FAM108C1 FAM57B FBF1 FCF1P2 FCN3 FES FURIN GLTP GOPC GTF2B HAUS8 HDAC7 HEXIM1 HOXA10 HOXB9 HOXC8 HRCT1 IPO11 JARID2 JPH2 KANK1 KAT2B KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 LDB3 LFNG LIME1 LOC338758 LSP1 MAP2K5 MED21 MGRN1 MPI MSRA MTHFR MYO9B NAT15 NCOA1 NDUFAF6 NEIL2 NELFCD NGF NOC3L NPPA-AS1 NPR3 NRBF2 NSUN6 NT5C2 NUCB2 OSGIN2 PDE1A PDLIM4 PDXK PHIP PIGV PLCB1 PMS2P5 PRDM8 PRKD3 PTPN12 PVRIG RGS19 RHOC RNASEH2C RNF34 RP11-296I10.6 RP11-436D10.3 RP11-538P18.2 RP11-588K22.2 RP11-613D13.5 RP11-810M2.2 RP4-635E18.7 RP4-671G15.2 RP5-1115A15.1 RPP25 RUVBL1 RYK SENP1 SENP3 SH2B3 SIK2 SLC2A4 SLC35F6 SLC4A7 SOX6 SPATA33 SRR STAG3L1 STK32C SWAP70 TBC1D19 TDRD1 TEAD2 TEX15 TH1L TMEM133 TMEM170A TNKS1BP1 TNNI2 TNNT3 TPD52L2 TSPY26P TUBB1 UBE2E3 UBL7 UFL1 ULK3 WDR66 WNT2B WNT3 YEATS4 ZBTB46 ZC3HC1 ZNF318 ZNF652 ZNF831 ZNRF3
Cholesterol lowering medication 2.44 5 2 4.4 0.53 3.6e-01 ABO DCAF16 KAT8 PIGV RNF34
Pain experienced in last month 1.35 2 0 0.0 0.00 1.0e+00 KAT8 UFL1
Basal cell carcinoma (self-reported) 1.23 1 0 0.0 0.00 1.0e+00 SPATA33
Heart attack/myocardial infarction (self-reported) 2.25 4 1 2.2 0.97 6.7e-03 FES SH2B3 ZC3HC1 ZNF652
Deep venous thrombosis (DVT) (self-reported) 2.70 1 1 2.2 0.00 1.0e+00 ABO
Heart disease (siblings) 1.67 2 0 0.0 0.00 1.0e+00 FES PVRIG
Pack years of smoking 1.23 1 0 0.0 0.00 1.0e+00 PMS2P5
Impedance of whole body 2.12 39 20 44.4 -0.39 1.2e-02 ABCF3 ABO ATG7 CENPW CEP41 CERS5 CISD2 CTB-31O20.6 EXOC4 FAM108C1 FAM57B HAUS8 HEXIM1 HOXC8 JPH2 KAT8 KCNK3 KLF16 LIME1 LSP1 MAP2K5 MSRA MYO9B NEIL2 NOC3L NT5C2 NUCB2 PDE1A PMS2P5 PRKD3 RP11-296I10.6 RYK SENP1 SENP3 SLC4A7 SRR STAG3L1 SWAP70 ZNF652
Leg fat mass (left) 2.05 25 14 31.1 0.82 5.0e-07 AC091133.1 COX5A CTB-31O20.6 FAM108C1 FAM57B KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 MAP2K5 MSRA NRBF2 PMS2P5 RP11-296I10.6 RP11-613D13.5 RP11-810M2.2 RP5-1115A15.1 RPP25 STAG3L1 STK32C TDRD1 TEAD2 TEX15 TSPY26P
Arm predicted mass (left) 1.83 28 11 24.4 0.24 2.2e-01 ABO C10orf118 CENPW CHMP1A CMIP DCAF16 FAM108C1 FAM57B HEXIM1 KAT8 KCNK3 KLF16 LIME1 MAP2K5 MSRA NCOA1 NEIL2 NPR3 NT5C2 PDE1A PDLIM4 RP11-613D13.5 SENP3 SH2B3 SLC35F6 STAG3L1 TEAD2 WDR66

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 31 0.89 3.0
GTEx Adipose Visceral Omentum 15 0.74 3.0
GTEx Adrenal Gland 13 0.89 2.9
GTEx Artery Aorta 41 1.38 3.1
GTEx Artery Coronary 8 0.68 2.9
GTEx Artery Tibial 37 0.98 3.0
GTEx Brain Caudate basal ganglia 5 0.54 2.9
GTEx Brain Cerebellar Hemisphere 14 0.94 2.9
GTEx Brain Cerebellum 15 0.76 3.0
GTEx Brain Cortex 8 0.77 3.1
GTEx Brain Frontal Cortex BA9 8 0.87 3.0
GTEx Brain Hippocampus 2 0.38 2.9
GTEx Brain Hypothalamus 2 0.34 2.6
GTEx Brain Nucleus accumbens basal ganglia 3 0.35 2.9
GTEx Brain Putamen basal ganglia 4 0.64 2.7
GTEx Breast Mammary Tissue 14 0.71 2.9
GTEx Breast Mammary Tissue (Male) 12 1.01 2.9
GTEx Breast Mammary Tissue (Female) 14 0.85 2.9
GTEx Cells EBV-transformed lymphocytes 8 0.56 2.9
GTEx Cells Transformed fibroblasts 34 0.81 2.9
GTEx Colon Sigmoid 11 0.75 2.9
GTEx Colon Transverse 16 0.78 2.9
GTEx Esophagus Gastroesophageal Junction 12 0.83 3.0
GTEx Esophagus Mucosa 28 0.84 2.9
GTEx Esophagus Muscularis 34 1.05 2.9
GTEx Heart Atrial Appendage 12 0.76 2.9
GTEx Heart Left Ventricle 15 0.98 3.0
GTEx Liver 3 0.42 2.7
GTEx Lung 22 0.77 3.0
GTEx Muscle Skeletal 18 0.62 2.9
GTEx Nerve Tibial 32 0.74 2.8
GTEx Ovary 11 1.21 3.3
GTEx Pancreas 12 0.74 2.9
GTEx Pituitary 9 0.81 2.9
GTEx Prostate 10 1.20 3.2
GTEx Skin Not Sun Exposed Suprapubic 25 1.02 3.0
GTEx Skin Sun Exposed Lower leg 38 1.04 2.9
GTEx Small Intestine Terminal Ileum 2 0.43 3.0
GTEx Spleen 11 0.78 2.8
GTEx Stomach 18 1.24 3.1
GTEx Testis 30 0.95 2.9
GTEx Thyroid 37 0.93 2.9
GTEx Uterus 6 1.06 2.8
GTEx Vagina 6 0.94 2.9
GTEx Whole Blood 13 0.65 2.8
METSIM Adipose 21 0.46 2.6
NTR Blood 20 0.83 2.8
ROSMAP Brain Pre-frontal Cortex 50 1.14 3.0
YFS Blood 25 0.54 2.6
CommonMind Brain Pre-frontal Cortex 44 0.82 2.7
The Cancer Genome Atlas Bladder Urothelial Carcinoma 10 0.60 2.6
The Cancer Genome Atlas Breast Invasive Carcinoma 33 0.75 2.6
The Cancer Genome Atlas Cervical Squamous Cell Carcinoma 4 0.36 2.6
The Cancer Genome Atlas Colon Adenocarcinoma 20 0.97 2.8
The Cancer Genome Atlas Esophageal Carcinoma 2 0.29 2.6
The Cancer Genome Atlas Glioblastoma Multiforme 5 0.49 2.6
The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma 17 0.62 2.7
The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma 41 1.00 2.8
The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma 15 0.73 2.7
The Cancer Genome Atlas Brain Lower Grade Glioma 29 0.67 2.6
The Cancer Genome Atlas Liver Hepatocellular Carcinoma 5 0.45 2.5
The Cancer Genome Atlas Lung Adenocarcinoma 23 0.78 2.6
The Cancer Genome Atlas Lung Squamous Cell Carcinoma 13 0.52 2.7
The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma 10 0.63 2.6
The Cancer Genome Atlas Pancreatic Adenocarcinoma 13 0.78 2.7
The Cancer Genome Atlas Pheochromocytoma and Paraganglioma 9 0.68 2.7
The Cancer Genome Atlas Prostate Adenocarcinoma 21 0.45 2.5
The Cancer Genome Atlas Rectum Adenocarcinoma 5 0.72 2.7
The Cancer Genome Atlas Soft Tissue Sarcoma 6 0.56 2.6
The Cancer Genome Atlas Skin Cutaneous Melanoma 2 0.37 2.7
The Cancer Genome Atlas Stomach Adenocarcinoma 13 0.77 2.8
The Cancer Genome Atlas Testicular Germ Cell Tumors 5 0.39 2.6
The Cancer Genome Atlas Thyroid Carcinoma 34 0.66 2.6
The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma 3 0.59 2.6