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chr6:134,905,567-136,516,257

Best TWAS P=1.6e-09 · Best GWAS P=1.09e-09 conditioned to 0.0585

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Tibial	AHI1	0.11	0.03	enet	16	0.09	1.8e-07	-4.9	5.5	3.4e-08	-0.80	0.04	0.95	FALSE
2	GTEx	Brain Cortex	RP3-388E23.2	0.28	0.16	enet	13	0.19	5.8e-06	-2.8	5.5	3.7e-08	-0.76	0.14	0.74	FALSE
3	GTEx	Brain Frontal Cortex BA9	AHI1	0.19	0.00	enet	14	0.05	1.5e-02	-1.1	5.6	2.2e-08	-0.35	0.07	0.18	TRUE
4	GTEx	Cells EBV-transformed lymphocytes	AHI1	0.38	0.24	enet	19	0.23	5.4e-08	-5.8	5.6	2.2e-08	-0.83	0.01	0.99	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	RP3-388E23.2	0.26	0.05	lasso	6	0.02	7.1e-02	-5.8	5.8	5.1e-09	-0.90	0.02	0.93	FALSE
6	GTEx	Cells Transformed fibroblasts	AHI1	0.44	0.21	enet	22	0.32	4.4e-24	-4.8	5.4	6.2e-08	-0.75	0.13	0.87	FALSE
7	GTEx	Esophagus Mucosa	AHI1	0.30	0.24	lasso	8	0.32	4.6e-22	-5.8	5.8	9.1e-09	-0.78	0.01	0.99	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	AHI1	0.41	0.31	lasso	7	0.40	9.1e-24	-5.8	6.0	1.9e-09	-0.81	0.01	0.99	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	RP3-388E23.2	0.14	0.03	enet	17	0.12	3.7e-07	-5.5	5.8	8.9e-09	-0.74	0.02	0.96	FALSE
10	GTEx	Skin Sun Exposed Lower leg	AHI1	0.33	0.22	enet	14	0.34	1.0e-28	-2.8	5.6	2.7e-08	-0.73	0.47	0.53	FALSE
11	GTEx	Skin Sun Exposed Lower leg	RP3-388E23.2	0.10	0.06	enet	6	0.04	3.1e-04	-5.6	5.5	4.1e-08	-0.85	0.06	0.91	FALSE
12	GTEx	Spleen	AHI1	0.31	0.21	lasso	3	0.38	8.6e-11	-5.5	5.9	3.4e-09	-0.72	0.02	0.94	FALSE
13	GTEx	Testis	AHI1	0.37	0.32	enet	25	0.37	3.5e-17	-5.8	5.3	1.4e-07	-0.79	0.01	0.99	FALSE
14	METSIM	Adipose	AHI1	0.25	0.22	lasso	7	0.28	1.1e-42	-5.8	5.7	1.4e-08	-0.79	0.01	0.99	FALSE
15	NTR	Blood	AHI1	0.11	0.14	lasso	6	0.15	3.2e-47	-5.8	5.5	4.6e-08	-0.78	0.01	0.98	FALSE
16	YFS	Blood	AHI1	0.24	0.30	bslmm	414	0.33	1.4e-110	-5.8	5.7	9.6e-09	-0.80	0.01	0.99	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	AHI1	0.06	0.02	lasso	7	0.02	1.3e-04	-5.8	5.8	5.6e-09	-0.78	0.01	0.99	FALSE
18	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	AHI1	0.18	0.19	lasso	4	0.18	6.4e-20	-5.8	5.9	3.4e-09	-0.82	0.01	0.99	FALSE
19	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	AHI1	0.13	0.16	lasso	3	0.16	1.2e-17	-5.8	6.0	2.0e-09	-0.82	0.01	0.99	FALSE
20	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	AHI1	0.05	0.05	lasso	1	0.04	1.5e-03	-5.8	5.8	8.7e-09	-0.82	0.01	0.90	FALSE
21	The Cancer Genome Atlas	Testicular Germ Cell Tumors	AHI1	0.36	0.30	lasso	3	0.29	1.0e-10	-5.8	6.0	1.6e-09	-0.84	0.01	0.99	TRUE