Best TWAS P=5.48e-09 · Best GWAS P=5.47e-26 conditioned to 4.73e-17
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | SLC35F6 | 0.10 | 0.04 | lasso | 4 | 0.05 | 4.2e-05 | -3.8 | 5.5 | 3.2e-08 | 0.37 | 0.45 | 0.08 | FALSE |
| 2 | METSIM | Adipose | SLC35F6 | 0.04 | 0.01 | blup | 362 | 0.02 | 1.1e-03 | 4.5 | 5.8 | 5.5e-09 | 0.48 | 0.10 | 0.46 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | KCNK3 | 0.24 | 0.15 | lasso | 3 | 0.15 | 6.5e-19 | 5.4 | -5.3 | 1.3e-07 | -0.34 | 1.00 | 0.00 | TRUE |
| 4 | The Cancer Genome Atlas | Esophageal Carcinoma | C2orf18 | 0.20 | 0.02 | blup | 30 | 0.06 | 6.7e-03 | 5.5 | 5.2 | 1.6e-07 | 0.45 | 0.01 | 0.55 | FALSE |