Best TWAS P=3.35e-08 · Best GWAS P=4.2e-09 conditioned to 0.333
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CNGA4 | 0.08 | 0.06 | enet | 12 | 0.07 | 2.1e-08 | 5.2 | 5.5 | 3.4e-08 | 0.81 | 0.01 | 0.99 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CNGA4 | 0.07 | 0.06 | lasso | 4 | 0.06 | 1.7e-07 | 5.9 | 5.5 | 4.5e-08 | 0.94 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | CNGA4 | 0.12 | 0.09 | blup | 60 | 0.09 | 8.2e-06 | 5.1 | 5.4 | 8.3e-08 | 0.78 | 0.00 | 0.99 | TRUE |