TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Medication: Cholesterol lowering
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chr8:144,294,773-145,744,618
Best TWAS P=9.81e-08 · Best GWAS P=3.79e-07 conditioned to 0.597
144.4M
144.6M
144.8M
145M
145.2M
145.4M
145.6M
145.8M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Esophagus Mucosa
PLEC
0.11
0.04
lasso
4
0.05
0.00027
5
-5.3
9.8e-08
-0.91
0.02
0.97
TRUE