Best TWAS P=1.81e-13 · Best GWAS P=7.96e-14 conditioned to 0.000269
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | LPL | 0.08 | 0.05 | bslmm | 667 | 0.06 | 5.5e-20 | -6.4 | -6.0 | 2.7e-09 | 0.79 | 0.11 | 0.89 | FALSE |
| 2 | YFS | Blood | LPL | 0.06 | 0.07 | lasso | 2 | 0.06 | 6.5e-20 | -6.6 | -6.5 | 6.4e-11 | 0.77 | 0.63 | 0.37 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LPL | 0.03 | 0.00 | blup | 88 | 0.00 | 1.3e-01 | -3.3 | -7.4 | 1.8e-13 | 0.63 | 0.04 | 0.41 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | LPL | 0.09 | 0.12 | lasso | 4 | 0.11 | 3.5e-12 | -5.9 | 5.9 | 3.1e-09 | -0.48 | 0.34 | 0.66 | FALSE |