TWAS
hub
About
Usage
Models
Genes
Traits
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Traits
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Medication: Cholesterol lowering
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chr8:19,064,892-20,521,138
Best TWAS P=1.81e-13 · Best GWAS P=7.96e-14 conditioned to 0.000269
19M
19.2M
19.4M
19.6M
19.8M
20M
20.2M
20.4M
20.6M
0
5
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
LPL
0.03
0.00
blup
88
0.00
1.3e-01
-3.3
-7.4
1.8e-13
0.63
0.04
0.41
TRUE
2
YFS
Blood
LPL
0.06
0.07
lasso
2
0.06
6.5e-20
-6.6
-6.5
6.4e-11
0.77
0.63
0.37
FALSE
1
NTR
Blood
LPL
0.08
0.05
bslmm
667
0.06
5.5e-20
-6.4
-6.0
2.7e-09
0.79
0.11
0.89
FALSE
4
The Cancer Genome Atlas
Brain Lower Grade Glioma
LPL
0.09
0.12
lasso
4
0.11
3.5e-12
-5.9
5.9
3.1e-09
-0.48
0.34
0.66
FALSE