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chr9:32,275,256-33,721,935

Best TWAS P=4.83e-08 · Best GWAS P=1.3e-07 conditioned to 0.403

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta APTX 0.10 0.14 lasso 2 0.12 6.8e-07 -5.3 -5.3 1.1e-07 1.00 0.00 1.00 FALSE
2 GTEx Brain Cerebellar Hemisphere APTX 0.23 0.09 lasso 6 0.11 1.1e-03 3.8 -5.1 2.8e-07 0.80 0.03 0.84 FALSE
3 GTEx Cells Transformed fibroblasts APTX 0.28 0.17 lasso 12 0.26 1.9e-19 -5.3 -5.5 4.8e-08 0.90 0.00 1.00 TRUE
4 GTEx Colon Sigmoid APTX 0.24 0.05 lasso 11 0.08 1.2e-03 4.9 -5.4 5.9e-08 0.78 0.02 0.95 FALSE
5 GTEx Pancreas APTX 0.19 0.08 lasso 7 0.04 5.7e-03 4.3 -5.2 2.1e-07 0.69 0.04 0.90 FALSE
6 GTEx Thyroid APTX 0.31 0.19 lasso 6 0.34 6.5e-27 3.4 -5.3 1.5e-07 0.85 0.03 0.95 FALSE
7 GTEx Vagina APTX 0.30 0.33 lasso 5 0.33 2.1e-08 -5.3 -5.2 2.1e-07 0.96 0.01 0.98 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SMU1 0.05 0.04 lasso 8 0.05 1.1e-06 -4.0 -5.2 2.3e-07 0.93 0.01 0.99 FALSE