Best TWAS P=9.3e-09 · Best GWAS P=6.87e-09 conditioned to 0.153
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | UBXN6 | 0.10 | 0.00 | enet | 21 | 0.02 | 8.0e-03 | -5.6 | -5.4 | 5.9e-08 | 0.61 | 0.02 | 0.94 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | UBXN6 | 0.09 | 0.10 | lasso | 1 | 0.08 | 1.5e-06 | -5.6 | -5.6 | 2.8e-08 | 0.92 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Heart Left Ventricle | UBXN6 | 0.21 | 0.14 | lasso | 6 | 0.16 | 5.6e-09 | -5.6 | -5.4 | 5.3e-08 | 0.90 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Prostate | MIR637 | 0.30 | -0.01 | lasso | 6 | -0.01 | 5.5e-01 | -5.6 | -5.6 | 1.8e-08 | 0.77 | 0.02 | 0.47 | FALSE |
| 5 | GTEx | Whole Blood | UBXN6 | 0.06 | 0.03 | lasso | 4 | 0.01 | 4.1e-02 | -5.5 | -5.7 | 1.4e-08 | 0.84 | 0.02 | 0.96 | FALSE |
| 6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | UBXN6 | 0.03 | 0.03 | lasso | 3 | 0.03 | 2.3e-06 | -5.6 | -5.7 | 9.3e-09 | 0.90 | 0.01 | 0.99 | TRUE |