TWAS hub - Supplements: Calcium

#	chr	p0	p1	# assoc genes	# joint genes	best TWAS P	best SNP P	cond SNP P	% var exp	joint genes
1	19	3268722	5153606	2	1	9.3e-09	6.9e-09	0.15	94	UBXN6

Trait	chisq ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	corr P	genes
Impedance of arm (right)	10.2	1	1	2.2	1	UBXN6
Impedance of whole body	9.6	1	1	2.2	1	UBXN6
Impedance of leg (right)	9.4	1	1	2.2	1	UBXN6
Impedance of arm (left)	9.2	1	1	2.2	1	UBXN6
Impedance of leg (left)	9.0	1	1	2.2	1	UBXN6
Blood Red Count	8.5	1	1	2.2	1	UBXN6
Supplements: Zinc	7.7	1	0	0.0	1	UBXN6
Arm predicted mass (right)	7.3	1	1	2.2	1	UBXN6
Arm fat-free mass (right)	7.1	1	1	2.2	1	UBXN6
Neuroticism	6.5	1	0	0.0	1	UBXN6
Arm fat-free mass (left)	6.3	1	1	2.2	1	UBXN6
Type 2 Diabetes (T2D) (2018)	6.2	1	0	0.0	1	UBXN6
Arm predicted mass (left)	6.1	1	1	2.2	1	UBXN6
Leg predicted mass (right)	5.8	1	1	2.2	1	UBXN6
Leg fat-free mass (right)	5.7	1	1	2.2	1	UBXN6
Whole body water mass	5.7	1	1	2.2	1	UBXN6
Guilty feelings	5.7	1	0	0.0	1	UBXN6
Leg fat-free mass (left)	5.6	1	1	2.2	1	UBXN6
Leg predicted mass (left)	5.6	1	1	2.2	1	UBXN6
Whole body fat-free mass	5.6	1	1	2.2	1	UBXN6
BMI	5.2	1	1	2.2	1	UBXN6
Hair/balding pattern: Pattern 3	5.2	1	0	0.0	1	UBXN6
Basal metabolic rate	5.1	1	1	2.2	1	UBXN6
Neuroticism (Nagel 2018)	4.9	1	0	0.0	1	UBXN6
Chronotype (morning person)	4.6	1	0	0.0	1	UBXN6
Peak expiratory flow (PEF)	4.6	1	0	0.0	1	UBXN6
Trunk fat-free mass	4.5	1	0	0.0	1	UBXN6
Trunk predicted mass	4.5	1	0	0.0	1	UBXN6
Qualifications: nursing, teaching	4.5	1	0	0.0	1	UBXN6
Worry too long after embarrassment	4.3	1	0	0.0	1	UBXN6
Weight	3.7	1	0	0.0	1	UBXN6
Body mass index (BMI)	3.4	1	0	0.0	1	UBXN6
Neuroticism score	3.4	1	0	0.0	1	UBXN6
Worry (Nagel 2018)	3.3	1	0	0.0	1	UBXN6
Waist circumference	3.3	1	0	0.0	1	UBXN6
Breast Cancer	3.1	1	0	0.0	1	UBXN6
Hip circumference	2.9	1	0	0.0	1	UBXN6
Lung FVC	2.8	1	0	0.0	1	UBXN6
Cardiovascular Disease	2.6	1	0	0.0	1	UBXN6
High blood pressure	2.6	1	0	0.0	1	UBXN6
Systolic Blood Pressure	2.5	1	0	0.0	1	UBXN6
Forced vital capacity (FVC)	2.1	1	0	0.0	1	UBXN6
Leg fat mass (right)	2.1	1	0	0.0	1	UBXN6
Leg fat mass (left)	2.1	1	0	0.0	1	UBXN6
Lung FEV1/FVC ratio	2.0	1	0	0.0	1	UBXN6
Arm fat mass (right)	1.9	1	0	0.0	1	UBXN6
Forced vital capacity (FVC), Best measure	1.9	1	0	0.0	1	UBXN6
Arm fat mass (left)	1.9	1	0	0.0	1	UBXN6
Hair Pigment	0.7	1	0	0.0	1	UBXN6

study	tissue	# hits	% hits/tests	avg chisq
GTEx	Brain Cerebellum	0	0.000	1.2
GTEx	Brain Cortex	0	0.000	1.2
GTEx	Brain Putamen basal ganglia	0	0.000	1.2
ROSMAP	Brain Pre-frontal Cortex	0	0.000	1.2
The Cancer Genome Atlas	Esophageal Carcinoma	0	0.000	1.2
The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	0	0.000	1.2
The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	0	0.000	1.2
The Cancer Genome Atlas	Pancreatic Adenocarcinoma	0	0.000	1.2
The Cancer Genome Atlas	Rectum Adenocarcinoma	0	0.000	1.2
The Cancer Genome Atlas	Skin Cutaneous Melanoma	0	0.000	1.2
GTEx	Adipose Subcutaneous	1	0.029	1.1
GTEx	Adipose Visceral Omentum	0	0.000	1.1
GTEx	Artery Aorta	0	0.000	1.1
GTEx	Artery Tibial	0	0.000	1.1
GTEx	Brain Cerebellar Hemisphere	0	0.000	1.1
GTEx	Brain Frontal Cortex BA9	0	0.000	1.1
GTEx	Brain Hypothalamus	0	0.000	1.1
GTEx	Brain Nucleus accumbens basal ganglia	0	0.000	1.1
GTEx	Breast Mammary Tissue	0	0.000	1.1
GTEx	Breast Mammary Tissue (Male)	0	0.000	1.1
GTEx	Breast Mammary Tissue (Female)	0	0.000	1.1
GTEx	Cells Transformed fibroblasts	1	0.024	1.1
GTEx	Colon Sigmoid	0	0.000	1.1
GTEx	Colon Transverse	0	0.000	1.1
GTEx	Esophagus Mucosa	0	0.000	1.1
GTEx	Esophagus Muscularis	0	0.000	1.1
GTEx	Heart Atrial Appendage	0	0.000	1.1
GTEx	Heart Left Ventricle	1	0.065	1.1
GTEx	Lung	0	0.000	1.1
GTEx	Muscle Skeletal	0	0.000	1.1
GTEx	Nerve Tibial	0	0.000	1.1
GTEx	Pancreas	0	0.000	1.1
GTEx	Pituitary	0	0.000	1.1
GTEx	Prostate	1	0.120	1.1
GTEx	Skin Not Sun Exposed Suprapubic	0	0.000	1.1
GTEx	Skin Sun Exposed Lower leg	0	0.000	1.1
GTEx	Small Intestine Terminal Ileum	0	0.000	1.1
GTEx	Spleen	0	0.000	1.1
GTEx	Stomach	0	0.000	1.1
GTEx	Testis	0	0.000	1.1
GTEx	Thyroid	0	0.000	1.1
GTEx	Uterus	0	0.000	1.1
GTEx	Vagina	0	0.000	1.1
GTEx	Whole Blood	1	0.050	1.1
METSIM	Adipose	0	0.000	1.1
NTR	Blood	0	0.000	1.1
YFS	Blood	0	0.000	1.1
CommonMind	Brain Pre-frontal Cortex	0	0.000	1.1
The Cancer Genome Atlas	Bladder Urothelial Carcinoma	0	0.000	1.1
The Cancer Genome Atlas	Breast Invasive Carcinoma	1	0.023	1.1
The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	0	0.000	1.1
The Cancer Genome Atlas	Colon Adenocarcinoma	0	0.000	1.1
The Cancer Genome Atlas	Glioblastoma Multiforme	0	0.000	1.1
The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	0	0.000	1.1
The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	0	0.000	1.1
The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	0	0.000	1.1
The Cancer Genome Atlas	Brain Lower Grade Glioma	0	0.000	1.1
The Cancer Genome Atlas	Lung Adenocarcinoma	0	0.000	1.1
The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	0	0.000	1.1
The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	0	0.000	1.1
The Cancer Genome Atlas	Prostate Adenocarcinoma	0	0.000	1.1
The Cancer Genome Atlas	Soft Tissue Sarcoma	0	0.000	1.1
The Cancer Genome Atlas	Stomach Adenocarcinoma	0	0.000	1.1
The Cancer Genome Atlas	Testicular Germ Cell Tumors	0	0.000	1.1
The Cancer Genome Atlas	Thyroid Carcinoma	0	0.000	1.1
The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	0	0.000	1.1
GTEx	Adrenal Gland	0	0.000	1.0
GTEx	Artery Coronary	0	0.000	1.0
GTEx	Brain Caudate basal ganglia	0	0.000	1.0
GTEx	Brain Hippocampus	0	0.000	1.0
GTEx	Cells EBV-transformed lymphocytes	0	0.000	1.0
GTEx	Esophagus Gastroesophageal Junction	0	0.000	1.0
GTEx	Liver	0	0.000	1.0
GTEx	Ovary	0	0.000	1.0

Hub : Traits :

Supplements: Calcium

Significant Loci

Pleiotropic Associations

Associations by panel