[Hub]/) : Traits : BMI : ← →

chr9:101,974,824-103,803,109

Best TWAS P=2.61e-16 · Best GWAS P=1.6e-16 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	INVS	0.10	0.04	bslmm	379	0.04	8.7e-06	-4.9	6.0	2.4e-09	0.34	0.49	0.07	FALSE
2	CommonMind	Brain Pre-frontal Cortex	TEX10	0.18	0.10	lasso	7	0.12	2.2e-14	-5.5	7.0	3.1e-12	0.65	0.81	0.19	FALSE
3	GTEx	Adipose Subcutaneous	INVS	0.12	0.09	enet	14	0.10	1.0e-08	3.4	6.2	5.3e-10	0.70	0.10	0.89	FALSE
4	GTEx	Adipose Subcutaneous	STX17	0.12	0.09	lasso	3	0.11	1.5e-09	5.3	5.2	2.5e-07	0.57	1.00	0.00	FALSE
5	GTEx	Adipose Visceral Omentum	INVS	0.29	0.13	enet	29	0.18	1.6e-09	3.4	5.7	1.2e-08	0.61	0.50	0.50	FALSE
6	GTEx	Adipose Visceral Omentum	STX17	0.14	0.10	lasso	7	0.10	4.6e-06	-5.3	5.8	7.1e-09	0.55	0.97	0.01	FALSE
7	GTEx	Artery Aorta	INVS	0.15	0.10	enet	19	0.12	4.9e-07	7.8	7.2	6.9e-13	0.72	0.22	0.74	FALSE
8	GTEx	Artery Tibial	STX17	0.07	0.05	lasso	2	0.06	1.4e-05	-5.3	5.5	2.9e-08	0.57	0.95	0.01	FALSE
9	GTEx	Brain Cerebellar Hemisphere	INVS	0.37	0.01	lasso	8	0.01	1.6e-01	6.1	6.0	2.0e-09	0.48	0.05	0.19	FALSE
10	GTEx	Breast Mammary Tissue	STX17	0.10	0.14	lasso	3	0.10	5.2e-06	-5.3	5.1	2.7e-07	0.47	0.97	0.01	FALSE
11	GTEx	Cells EBV-transformed lymphocytes	INVS	0.14	0.04	lasso	10	0.04	1.4e-02	5.3	5.5	3.1e-08	0.59	0.36	0.26	FALSE
12	GTEx	Cells Transformed fibroblasts	INVS	0.16	0.10	enet	17	0.17	8.0e-13	7.7	6.9	3.8e-12	0.61	0.24	0.76	FALSE
13	GTEx	Cells Transformed fibroblasts	STX17	0.19	0.19	lasso	6	0.19	4.4e-14	-5.0	5.2	1.8e-07	0.46	1.00	0.00	FALSE
14	GTEx	Colon Sigmoid	INVS	0.26	0.11	lasso	5	0.23	1.6e-08	-5.0	5.8	5.4e-09	0.62	0.56	0.33	FALSE
15	GTEx	Esophagus Gastroesophageal Junction	INVS	0.27	0.23	enet	30	0.24	3.6e-09	3.4	6.2	6.3e-10	0.55	0.60	0.33	FALSE
16	GTEx	Esophagus Mucosa	INVS	0.16	0.04	enet	20	0.07	2.4e-05	2.6	5.9	4.2e-09	0.51	0.36	0.26	FALSE
17	GTEx	Esophagus Mucosa	STX17	0.19	0.26	lasso	9	0.27	2.5e-18	5.2	5.5	3.9e-08	0.58	1.00	0.00	FALSE
18	GTEx	Esophagus Muscularis	INVS	0.21	0.16	lasso	5	0.22	8.9e-14	7.7	7.0	2.2e-12	0.73	0.23	0.77	FALSE
19	GTEx	Heart Atrial Appendage	INVS	0.08	0.03	lasso	3	0.04	4.9e-03	-5.6	6.8	1.4e-11	0.77	0.08	0.85	FALSE
20	GTEx	Heart Left Ventricle	INVS	0.11	0.05	enet	15	0.04	2.6e-03	3.4	7.3	2.4e-13	0.72	0.04	0.84	FALSE
21	GTEx	Muscle Skeletal	INVS	0.12	0.03	lasso	10	0.10	1.3e-09	7.7	7.0	3.1e-12	0.73	0.07	0.93	FALSE
22	GTEx	Skin Not Sun Exposed Suprapubic	TEX10	0.10	0.09	lasso	4	0.10	3.1e-06	5.4	7.1	1.2e-12	0.92	0.02	0.98	FALSE
23	GTEx	Skin Sun Exposed Lower leg	INVS	0.19	0.06	enet	30	0.11	1.5e-09	7.7	7.7	1.6e-14	0.79	0.02	0.98	FALSE
24	GTEx	Skin Sun Exposed Lower leg	TEX10	0.27	0.27	lasso	8	0.28	7.0e-23	8.2	8.2	2.6e-16	1.00	0.00	1.00	TRUE
25	GTEx	Small Intestine Terminal Ileum	STX17	0.14	0.06	lasso	2	0.08	9.3e-03	-5.4	5.6	1.8e-08	0.53	0.11	0.16	FALSE
26	GTEx	Stomach	INVS	0.23	0.13	lasso	9	0.14	4.4e-07	-5.3	5.9	4.4e-09	0.55	0.92	0.06	FALSE
27	GTEx	Thyroid	INVS	0.22	0.11	enet	18	0.18	5.0e-14	7.7	6.5	8.1e-11	0.65	0.24	0.76	FALSE
28	GTEx	Whole Blood	INVS	0.07	0.02	enet	9	0.05	2.8e-05	2.6	6.5	7.5e-11	0.70	0.27	0.52	FALSE
29	METSIM	Adipose	INVS	0.14	0.09	lasso	11	0.16	6.7e-24	3.7	6.3	3.7e-10	0.66	0.73	0.27	FALSE
30	NTR	Blood	INVS	0.01	0.01	lasso	4	0.01	3.6e-04	-3.3	6.5	7.6e-11	0.57	0.25	0.37	FALSE
31	YFS	Blood	INVS	0.15	0.14	lasso	7	0.24	1.4e-77	3.7	7.2	7.9e-13	0.78	0.01	0.99	FALSE
32	YFS	Blood	TEX10	0.03	0.02	blup	368	0.02	1.7e-06	5.4	-5.6	2.7e-08	-0.76	0.03	0.97	FALSE
33	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	INVS	0.27	0.05	lasso	8	0.13	3.4e-11	6.1	6.6	4.6e-11	0.68	0.19	0.81	FALSE
34	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	STX17	0.16	0.17	lasso	2	0.16	7.4e-14	-5.3	5.3	1.3e-07	0.48	0.02	0.98	FALSE
35	The Cancer Genome Atlas	Breast Invasive Carcinoma	INVS	0.22	0.04	lasso	9	0.07	7.3e-15	7.3	6.7	2.0e-11	0.71	0.40	0.60	FALSE
36	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	INVS	0.10	0.03	blup	107	0.07	4.0e-04	8.0	7.3	3.0e-13	0.89	0.02	0.95	FALSE
37	The Cancer Genome Atlas	Colon Adenocarcinoma	STX17	0.12	0.09	lasso	4	0.08	2.1e-05	-5.4	5.4	8.1e-08	0.47	0.02	0.97	FALSE
38	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	INVS	0.10	0.08	lasso	5	0.07	3.4e-08	-5.0	5.8	6.9e-09	0.58	0.99	0.01	FALSE
39	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	INVS	0.13	0.05	blup	106	0.03	1.3e-04	-5.0	5.6	2.3e-08	0.59	0.96	0.04	FALSE
40	The Cancer Genome Atlas	Lung Adenocarcinoma	INVS	0.08	0.06	blup	106	0.07	7.0e-09	-5.0	6.9	5.8e-12	0.70	0.92	0.08	FALSE
41	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	INVS	0.09	0.02	enet	11	0.04	4.0e-05	6.1	6.7	1.9e-11	0.66	0.02	0.77	FALSE
42	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	INVS	0.16	0.12	enet	8	0.08	2.8e-04	7.3	7.7	1.0e-14	0.77	0.16	0.77	FALSE
43	The Cancer Genome Atlas	Prostate Adenocarcinoma	INVS	0.09	0.04	enet	14	0.06	1.5e-06	6.1	7.1	1.4e-12	0.75	0.04	0.94	FALSE
44	The Cancer Genome Atlas	Stomach Adenocarcinoma	INVS	0.07	0.12	lasso	7	0.10	1.4e-07	-5.4	5.5	4.6e-08	0.53	0.95	0.04	FALSE
45	The Cancer Genome Atlas	Stomach Adenocarcinoma	STX17	0.07	0.05	lasso	1	0.05	2.1e-04	-5.3	5.3	9.0e-08	0.47	0.02	0.95	FALSE
46	The Cancer Genome Atlas	Thyroid Carcinoma	INVS	0.21	0.07	enet	13	0.18	4.0e-17	-5.1	6.7	1.5e-11	0.71	0.24	0.76	FALSE
47	The Cancer Genome Atlas	Thyroid Carcinoma	STX17	0.07	0.03	blup	56	0.05	2.2e-05	-5.4	5.6	2.1e-08	0.55	0.02	0.93	FALSE