Best TWAS P=4.16e-09 · Best GWAS P=3.22e-12 conditioned to 2.62e-08
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | TMEM126A | 0.07 | 0.09 | lasso | 3 | 0.08 | 2.2e-07 | -4.7 | 5.2 | 2.5e-07 | 0.36 | 0.24 | 0.76 | FALSE |
2 | GTEx | Adrenal Gland | TMEM126A | 0.11 | 0.05 | lasso | 3 | 0.06 | 4.0e-03 | -5.2 | 5.3 | 1.2e-07 | 0.27 | 0.03 | 0.87 | FALSE |
3 | GTEx | Nerve Tibial | TMEM126A | 0.07 | 0.04 | lasso | 6 | 0.03 | 2.7e-03 | -6.0 | 5.9 | 4.2e-09 | 0.28 | 0.01 | 0.99 | TRUE |